CAS 223463-13-6 5-Bromo-2-iodopyridine products price,suppliers

Aqueous HI (57 percent) was added to 2, 5-dibromopyridine (12.60 g, 53.2 mmol) and Nal (11.40 g, 76 mmol). The resulting mixture was heated at reflux for 24 h, cooled and thendiluted with water (100 mL). The resulting mixture was basified with NaHCO3 and treated with Na2S2O4 until colourless. The mixture was extracted with DCM (5 x 60 mL) and the dried (Na2SO4) solvent removed under reduced pressure. The residue was collected by filtration and washed with Et20 (60 mL) and air dried to give the 5-bromo-2-iodopyridine (8.28 g, 55 percent) as a light grey powder.