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Home> Products > Pharmaceuticals and Biochemicals > Blood System Agents > CAS DataBase Listed 2 > CAS 287714-41-4
287714-41-4 structure 3D

CAS 287714-41-4 products price,suppliers

  • Name: Glycine, N-[(hydroxymethylphosphinyl)methyl]-
  • Molecular Weight: 506.539
  • Formula: C10H10F3N3O7S
  • Synonyms: (3R,5S,6E)-7-[4-(4-fluorophenyl)-2-(N-MethylMethanesulfonaMido)-6-(propan-2-yl)pyriMidin-5-yl]-3,5-dihydroxyhept-6-enoic acid; (3R,5S,E)-7-(4-(4-Fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid; 7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-(methyl-methylsulfonyl-amino)-pyrimidin-5-yl]-3,5-dihydroxy-hept-6-enoic acid; R-2: TERT-BUTYL-(+) 7-[4-(4-FLUOROPHENYL)-6-ISOPROPYL-2-(N-METHYLSULFONYLAMINO) PYRIMIDINE-5-YL]-(3R, 5S)-DIOXANE-(E)-6-HEPTENATE; Rosuvastatin Acid; Rosuvastatin Impurity 21;
  • Rosuvastatin is a competitive inhibitor of HMG-CoA reductase with IC50 of 11 nM. IC50 Value: 11 nM [1]Target: HMG-CoA reductasein vitro: Rosuvastatin is relatively hydrophilic and is highly selective for hepatic cells; its uptake is mediated by the liver-specific organic anion transporter OATP-C. Rosuvastatin is a high-affinity substrate for OATP-C with apparent association constant of 8.5 μM [2]. Rosuvastatin inhibits cholesterol biosynthesis in rat liver isolated hepatocytes with IC50
Properties Safety and Handling MSDS Synthesis Route Precursor and Product Computational chemical data
Identification Safety Data
Properties
  • Molecular Weight:
  • 506.539
  • Melting Point:
  • 210-218°C
  • Refractive index:
  • 1.597
  • Solubility:
  • In water, 41 mg/L at 25 deg C /Estimated/
  • Stability:
  • Stable under recommended storage conditions. /Rosuvastatin calcium;/
  • More Properties>>
Question & Answer
  • What is rosuvastatin? What is rosuvastatin? Rosuvastatin is a prescription drug. It comes in the form of a tablet you take by mouth.Rosuvastatin is available as the brand-name drug Crestor. It’s also available as a generic drug. Generic drugs usually cost less than the brand-name version. In some cases, they may n...more+ Apr 10 2021
Upstream Product Downtream information
There are 133 suppliers who can provide Glycine, N-[(hydroxymethylphosphinyl)methyl]- with CAS No. 287714-41-4
Factory Supply Rosuvastatin CAS 287714-41-4
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7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-(methyl-methylsulfonyl-amino)-pyrimidin-5-yl]-3,5-dihydroxy-hept-6-enoic acid; Rosuvastatin ; 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-(methyl-methylsulfonyl-amino)-pyrimidin-5-yl]-3,5-dihydroxy-hept-6-enoic acid
7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-(methyl-methylsulf...
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  • Description:Rosuvastatin Basic information Description Indications and Usage Mechanisms of Action Pharmacokinetics Drug Interactions Adverse Effects References Product Name: Rosuvastatin Synonyms: ROSUVASTATIN-D3 SODIUM SALT;7-[4-(4-Fluorophenyl)-6-(1-methylethyl)-2-(meth...
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  • Description:Name: Rosuvastatin (Related Reference) Molecular Formula: C22H28FN3O6S CAS Registry Number: 287714-41-4 Synonyms: (E)-(3R,5S)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methylsulfonyl)(methyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoicacid; 6-heptenoic acid, 7-...
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CAS 287714-41-4 RosuvastatinCAS: 	 		 	 	287714-41-4
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  • Description:Name: RosuvastatinSynonyms: (E)-(3R,5S)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[(methylsulfonyl)(methyl)amino]pyrimidin-5-yl]-3,5-dihydroxyhept-6-enoicacid;6-heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,...
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  • Description:EC NO: INCHI:InChI=1/C22H28FN3O6S/c1-13(2)20-18(10-9-16(27)11-17(28)12-19(29)30)21(14-5-7-15(23)8-6-14)25-22(24-20)26(3)33(4,31)32/h5-10,13,16-17,27-28H,11-12H2,1-4H3,(H,29,30)/b10-9+/t16-,17+/m0/s1 MF:C22H28FN3O6S MW:481.54 Synonyms: 7-[4-(4-fluorophenyl)-6-(...
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