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Home> Products > Organic Intermediates > Pharmaceutical Intermediates > CAS DataBase Listed 3 > CAS 330784-47-9
330784-47-9 structure 3D

CAS 330784-47-9 products price,suppliers

  • Name: Carbamic acid,[4-[(3,5-dimethylphenyl)thio]-1,2-dihydro-5-methyl-2-oxo-3-pyridinyl]-, ethylester (9CI)
  • Molecular Weight: 483.95064
  • Formula: C5H11NO
  • Synonyms: (S)-4-((3-Chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-yl; (S)-4-((3-Chloro-4-Methoxybenzyl)aMino)-2-(2-(hydroxyMethyl)pyrrolidin-1-yl)-N-(pyriMidin-2-ylMethyl)pyriMidine-5-carboxaMide; 4-((3-chloro-4-Methoxybenzyl)aMino)-2-(2-(hydroxyMethyl)pyrrolidin-1-yl)-N-(pyriMidin-2-ylMethyl)pyriMidine-5-carboxaMide; 4-[[(3-Chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-N-(2-pyriMidinylMethyl)-5-pyriMidinecarboxaMide; Avanafil 4-[(3-Chloro-4-methoxybenzyl)amino]-2-[2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-5-pyrimidinecarboxamide; Avanafil PDE5 inhibitor;
  • Avanafil(TA-1790) is a potent and highly selective phosphodiesterase-5(PDE-5) inhibitor(IC50=5.2 nM) for erectile dysfunction; lower selectivity against PDE1, PDE6, and PDE11.IC50 value: 5.2 nM [1]Target: PDE5Avanafil is highly selective toward PDE5 and against all other PDE isozymes tested. Lower selectivity against PDE1, PDE6, and PDE11 is consistent with results from randomized, placebo-controlled, phase 3 trials in which musculoskeletal and hemodynamic adverse events were reported in
Properties Safety and Handling MSDS Synthesis Route Precursor and Product Computational chemical data
Identification
Safety Data
Properties
  • Appearance:
  • White solid
  • Molecular Weight:
  • 483.95064
  • Density:
  • 1.08
  • Boiling Point:
  • 155.6 DEG C @ 760 MM HG; 132.5 DEG C @ 400 MM HG; 110.3 DEG C @ 200 MM HG; 90.4 DEG C @ 100 MM HG; 77.5 DEG C @ 60 MM HG; 67.8 DEG C @ 40 MM HG; 52.5 DEG C @ 20 MM HG; 38.7 DEG C @ 10 MM HG; 26.4 DEG C @ 5 MM HG; 1.4 DEG C @ 1.0 MM HG
  • Melting Point:
  • 150-152 °C
  • Storage Temperature:
  • Refrigerator
  • Refractive index:
  • 1.651
  • More Properties>>
Upstream Product Downtream information
There are 219 suppliers who can provide Carbamic acid,[4-[(3,5-dimethylphenyl)thio]-1,2-dihydro-5-methyl-2-oxo-3-pyridinyl]-, ethylester (9CI) with CAS No. 330784-47-9
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Avanafil
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  • Description:4-[[(3-Chloro-4-Methoxyphenyl)Methyl]aMino]-2-[(2S)-2-(hydroxyMethyl)-1-pyrrolidinyl]-N-(2-pyriMidinylMethyl)-5-pyriMidinecarboxaMide;4-((3-chloro-4-Methoxybenzyl)aMino)-2-(2-(hydroxyMethyl)pyrrolidin-1-yl)-N-(pyriMidin-2-ylMethyl)pyriMidine-5-carboxaMide;Avan...
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5-Pyrimidinecarboxamide,4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-
5-Pyrimidinecarboxamide,4-[[(3-chloro-4-methoxyphenyl)methyl...
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5-Pyrimidinecarboxamide,4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-
5-Pyrimidinecarboxamide,4-[[(3-chloro-4-methoxyphenyl)methyl...
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5-Pyrimidinecarboxamide,4-[[(3-chloro-4-methoxyphenyl)methyl]amino]-2-[(2S)-2-(hydroxymethyl)-1-pyrrolidinyl]-N-(2-pyrimidinylmethyl)-
5-Pyrimidinecarboxamide,4-[[(3-chloro-4-methoxyphenyl)methyl...
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(S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide
(S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)...
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Avanafil
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  • Description:Avanafil Aliase: (S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidin-1-yl)-N-(pyrimidin-2-ylmethyl)pyrimidine-5-carboxamide CAS: 330784-47-9 Molecular Formula:C23H26ClN7O3 Molecular Weight:483.9506 Assay: 99% min. Appearance: White to Off-Wh...
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high quality Avanafil CAS NO.330784-47-9
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