Identification
- Cas NO.:443913-73-3
- CID:3081361
- Name:
- Vandetanib (Related Reference)
- InChI:
- InChI=1S/C22H24BrFN4O2/c1-28-7-5-14(6-8-28)12-30-21-11-19-16(10-20(21)29-2)22(26-13-25-19)27-18-4-3-15(23)9-17(18)24/h3-4,9-11,13-14H,5-8,12H2,1-2H3,(H,25,26,27)
Safety Data
Properties
- Molecular Weight:
- 475.362
- Density:
- 1.406
- Boiling Point:
- 538.2 °C at 760 mmHg
- Melting Point:
- 240-243oC
- Flash Point:
- 279.3 °C
- Storage Temperature:
- -20?C Freezer
- Refractive index:
- 1.629
- Solubility:
- Soluble in DMSO
- Stability:
- Vandetanib; solid is found to be stable to both thermal and hydrolytic degradation but a small degree of degradation is observed under stressed photolytic conditions. In solution, vandetanib; is degraded under acidic, oxidative and light stress conditions but it is stable under basic conditions.
- More Properties>>
Question & Answer
-
Vandetanib- Application in Cancer Therapy
Figure 1. Structural formula of vandetanib Vandetanib is a multiple signal transduction inhibitor including the RET tyrosine kinase, epidermal growth factor receptor (EGFR), vascular endothelial growth factor (VEGF) receptor (VEGFR), ERK and with antiangiogenic activity. Therefore, it has good anti...more+
Nov 24 2020
Upstream Product
Downtream information
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- Description:Name: Vandetanib (Related Reference) Molecular Formula: C22H24BrFN4O2 CAS Registry Number: 443913-73-3 Synonyms: 4-(4-Bromo-2-fluoroanilino)-6-methoxy-7-[(1-methylpiperidin-4-yl)methoxy]quinazoline; Vandetanib, Zactima, ZD6474 InChI: InChI=1S/C22H24BrFN4O2/c1-...
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