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Home> Products > Organic Intermediates > Pharmaceutical Intermediates > CAS DataBase Listed 4 > CAS 459168-41-3
459168-41-3 structure

CAS 459168-41-3 JNJ7777120 | Products & Prices & Suppliers

  • JNJ-7777120 is a selective H4R antagonist with Ki of 4 ±1 nM, exhibits >1000-fold selectivity over the other histamin receptors.IC50 value: 4 ±1 nM (Ki) [1] Target: histamine H4 receptorin vitro: JNJ-7777120 prevents fibronectin-induced lung fibroblast migration, thus suggesting that H4R could represent an attractive target for the development of new drugs for lung fibrosis treatment .[2]in vivo: JNJ 7777120 blocks histamine-induced chemotaxis and calcium influx in mouse bone marrow-deri

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  • Name: JNJ7777120
  • Molecular Weight: 277.7493
  • Formula: C14H16ClN3O
  • Synonyms: (5-Chloro-1H-indol-2-yl)(4-methyl-1-piperazinyl)methanone; (5-Chloro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone; (5-Chloro-1H-indol-2-yl)(4-methylpiperazin-1-yl)methanone JNJ 7777120; CS-593; JNJ 7777120; JNJ-7777120;
Properties Safety and Handling Synthesis Route Precursor and Product Computational chemical data
Identification
Safety Data
  • [Risk Codes]
  • R36/37/38:Irritating to eyes, respiratory system and skin
  • [Safety Statements]
Properties
  • Molecular Weight:
  • 277.7493
  • Density:
  • 1.322
  • Boiling Point:
  • 477°C at 760 mmHg
  • Flash Point:
  • 242.3°C
  • Refractive index:
  • 1.655
  • Solubility:
  • H2O: insoluble
  • More Properties>>
Upstream Product Downtream information
There are 19 suppliers who can provide JNJ7777120 with CAS No. 459168-41-3
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JNJ-7777120  459168-41-3 supplier
JNJ-7777120 459168-41-3 supplier
  • Min.Order:1 Milligram 
  • Supply Ability:100 Metric Ton/Year 
  • Appearance:powder 
  • Purity:99% 
  • Packaging:as your required 
  • Description:Superiority nanjing sunsure chemical technology co., ltd., established in 2009, has expanded a compositive entity from initially only as a small manufacturer. the company dedicated to the development, production and marketing of chemicals. sunsure covers whole...
  • Updatetime:Feb 25 2019 
JNJ-7777120
JNJ-7777120
  • Packaging:1kg5kg10kg50kg100kg 
  • Usage:Organic intermediates 
  • Brand:J&H Chemical 
  • Description:Hangzhou J&H Chemical Co., Ltd is one of China's leading providers of integrated fine chemical services including offering, research and development, Custom manufacturing business, as well as other Value-added customer services, for diversified range products ...
  • Updatetime:Dec 14 2017 
Methanone,(5-chloro-1H-indol-2-yl)(4-methyl-1-piperazinyl)-
Methanone,(5-chloro-1H-indol-2-yl)(4-methyl-1-piperazinyl)-
  • FOB Price:Inquiry USD/gram 
  • Min.Order:1 Gram 
  • Supply Ability:100 Gram/Day 
  • Appearance:white or yellowish crystalline powder 
  • Packaging:as requested 
  • Brand:Boc Sciences 
  • Description:Name:Methanone,(5-chloro-1H-indol-2-yl)(4-methyl-1-piperazinyl)- CAS NO:459168-41-3 Molecular Formula:C14H16 Cl N3 O Molecular Weight:C14H16ClN3OMelting Point:50-54℃ Stability:Stable. Combustible. Incompatible with strong oxidizing agents, ammonia.
  • Updatetime:Mar 29 2016 
JNJ7777120
JNJ7777120
  • Purity:98% 
  • Packaging:1g,5g,10g,100g,1000g, 
  • Description:Superiority best quality & attractive price & professional service; kailiqi biopharma is leading by professional teams for years and is qualified as the superior supplier of merck, novartis, mitsui chemicals. kailiqi biopharma develop produce and distribute hi...
  • Updatetime:Feb 25 2019 
CAS 459168-41-3, JNJ7777120, C14H16ClN3O
CAS 459168-41-3, JNJ7777120, C14H16ClN3O
  • Min.Order:0 Metric Ton 
  • Supply Ability:Metric Ton/Day 
  • Purity:99% 
  • Description:Superiority cas 459168-41-3, jnj7777120, c14h16cln3o Details Keywords:CAS 459168-41-3, JNJ7777120, C14H16ClN3O,STOCK,good price
  • Updatetime:Feb 25 2019 
JNJ 7777120
JNJ 7777120
  • Min.Order:0 Metric Ton 
  • Supply Ability:Metric Ton/Day 
  • Purity:98 
  • Description:Superiority name:jnj 7777120 cas no.:459168-41-3 Details Name:JNJ 7777120 CAS NO.:459168-41-3 Keywords:JNJ 7777120,459168-41-3,JNJ7777120
  • Updatetime:Feb 24 2019 
JNJ 7777120
JNJ 7777120
  • Purity:99% 
  • Description:Superiority we have two r&d center both in suzhou and nanjing. the r&d center owns labs with 2500m479 production base. and excellent staff, advanced equipments ,instruments, strict quality management system enhance our competitiveness.we are good at rare&hard ...
  • Updatetime:Feb 23 2019 
JNJ 7777120
JNJ 7777120
  • Min.Order:1 Gram 
  • Supply Ability:100 Gram/Quarter 
  • Purity:99% 
  • Description:Molecular Formula: C14H16ClN3O Formula Weight: 277.753 CAS No.: 459168-41-3
  • Updatetime:Jan 09 2013 
1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methyl-piperazine
1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methyl-piperazine
  • Purity:98% 
  • Updatetime:Apr 01 2019 
1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methyl-piperazine
1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methyl-piperazine
  • Purity:98% 
  • Updatetime:Apr 01 2019 
1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methyl-piperazine
1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methyl-piperazine
  • Purity:98% 
  • Updatetime:Apr 01 2019 
1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methyl-piperazine
1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methyl-piperazine
  • Purity:99% 
  • Updatetime:Apr 01 2019 
1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methyl-piperazine
1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methyl-piperazine
  • Purity:98% 
  • Updatetime:Apr 01 2019 
1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methyl-piperazine
1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methyl-piperazine
  • Purity:98% 
  • Updatetime:Apr 01 2019 
Methanone,(5-chloro-1H-indol-2-yl)(4-methyl-1-piperazinyl)-
Methanone,(5-chloro-1H-indol-2-yl)(4-methyl-1-piperazinyl)-
  • Description:Methanone,(5-chloro-1H-indol-2-yl)(4-methyl-1-piperazinyl)-
  • Updatetime:Apr 25 2014 
JNJ-7777120
JNJ-7777120
  • Updatetime:Nov 25 2019 
JNJ-7777120
JNJ-7777120
  • Updatetime:Nov 25 2019 
JNJ 7777120;1-[(5-Chloro-1H-indol-2-yl)carbonyl]-4-methylpiperazine
Methanone,(5-chloro-1H-indol-2-yl)(4-methyl-1-piperazinyl)-
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