Floxuridine (5-fluorodeoxyuridine) is an oncology drug that belongs to the class known as antimetabolites with an GI50 of 5.1 μM for the inhibition of PEPT1. IC50 value: Target: Nucleoside antimetabolite/analogFloxuridine (Fludara) is a prodrug of floxuridine and an oncology agent with an GI50 of 5.1 μM for the inhibition of MDCK/PEPT1. Floxuridine (Fludara) belongs to the class known as antimetabolites. Floxuridine (Fludara) is most often used in the treatment of colorectal cancer. Flox
R36/37/38:Irritating to eyes, respiratory system and skin
R68:Possible risk of irreversible effects
[Safety Statements]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection
Hazard Symbols:
HazardClass:6.1
Properties
Appearance:
white to off-white crystalline powder
Molecular Weight:
246.192443
Density:
1.62
Melting Point:
148-153℃
Alpha:
35.9 o (C=1, WATER)
Storage Temperature:
2-8°C
Refractive index:
1.608
Solubility:
1 g in about 4.5 ml isopropanol, about 7.5 ml methanol, about 12 ml alcohol, about 27 ml acetone; insol in chloroform, ether, and benzene In water, 1.2X10+4 mg/L at 25 deg C (est)
Stability:
Stable. Incompatible with strong oxidizing agents.
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