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Home> Products > Pharmaceuticals and Biochemicals > Herbal Extract > CAS DataBase Listed 5 > CAS 5508-58-7
5508-58-7 structure

CAS 5508-58-7 Andrographolide products price,suppliers

  • Andrographolide is a NF-κB inhibitor, which inhibits NF-κB activation through covalent modification of a cysteine residue on p50 in endothelial cells without affecting IκBα degradation or p50/p65 nuclear translocation.

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  • Name: Andrographolide
  • Molecular Weight: 350.4492
  • Formula: C20H30O5
  • Synonyms: (3E)-3-[2-[(1R,8aS)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-3,4,4a,6,7,8-hexahydro-1H-naphthalen-1-yl]ethylidene]-4-hydroxy-2-oxolanone; (3E)-3-[2-[(1S,8aR)-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylidene-decalin-1-yl]ethylidene]-4-hydroxy-oxolan-2-one; (3E,4S)-3-[2-[(1R,4aS,5R,6R,8aS)-Decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-2(3H)-furanone; 2(3H)-Furanone, 3-(2-(decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl)ethylidene)dihydro-4-hydroxy-, (1R-(1-alpha(E(S*)),4a-beta,5-alpha,6-alpha,8a-alpha))-; 2(3H)-Furanone, 3-[2-[(1R,4aS,5R,6R,8aS)-decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-, (3E,4S)-; 2(3H)-Furanone, 3-[2-[decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-;
Properties Safety and Handling MSDS Computational chemical data
Identification
  • Cas NO.:5508-58-7
  • CID:5318517
  • Name:
  • Andrographolide (Related Reference)
  • EINECS:
  • 226-852-5
  • InChI:
  • InChI=1S/C20H30O5/c1-12-4-7-16-19(2,9-8-17(23)20(16,3)11-21)14(12)6-5-13-15(22)10-25-18(13)24/h5,14-17,21-23H,1,4,6-11H2,2-3H3/b13-5+/t14-,15-,16+,17-,19+,20+/m1/s1
Safety Data
  • [Risk Codes]
  • R20/21/22:Harmful by inhalation, in contact with skin and if swallowed
  • [Safety Statements]
  • S22:Do not breathe dust
  • S24/25:Avoid contact with skin and eyes
Properties
  • Molecular Weight:
  • 350.4492
  • Density:
  • 1.21
  • Boiling Point:
  • 557.3 °C at 760 mmHg
  • Melting Point:
  • 229-232℃
  • Flash Point:
  • 557.3 °C at 760 mmHg
  • Alpha:
  • -126 o (C=1.5,HAC)
  • Storage Temperature:
  • Keep tightly closed. Store in a cool dry place.
  • Refractive index:
  • 1.567
  • Solubility:
  • Insoluble
  • More Properties>>
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  • Description:PRODUCT DETAILS Andrographolide is a NF-κB inhibitor, which inhibits NF-κB activation through covalent modification of a cysteine residue on p50 in endothelial cells without affecting IκBα degradation or p50/p65 nuclear translocation. Density 1.2±0.1 g/cm3...
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  • Description:Hot Production CAS 28578-16-7 CAS 110-64-5 CAS 7331-52-4 NMP CAS 102-97-6 JWH 018 SGT 263 SGT 151 5cl/5f adbb ad-18 EU ETI,14188 6cl 8cl 6 brad
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  • Description:ent-(3β,12E,14R)-3,14,19-Trihydroxy-8(17),12-labdadien-16,15-olide;Andrographolide/Andrographis Paniculata P.E.;5-alpha,6-alpha,8a-alpha))-t;2(3h)-furanone,3-(2-(decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-met;3-(2-(Decahydro-6-hydroxy-5-(hydroxymet...
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  • Description:Name: Andrographolide Synonyms: 2(3H)-Furanone, 3-[2-[(1R,4aS,5R,6R,8aS)-decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dimethyl-2-methylene-1-naphthalenyl]ethylidene]dihydro-4-hydroxy-, (3E,4S)-;2(3H)-Furanone, 3-(2-(decahydro-6-hydroxy-5-(hydroxymethyl)-5,8a-dim...
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  • Description:Product name Andrographolide Synonyms Andrographolide CAS No. 5508-58-7 Molecular Formula C20H30O5 Molecular Weight 350.45 Appearance white powder Assay 98% Application Used as pharmaceutical intermediates Packing as required
  • Updatetime:Jun 01 2023 
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