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Home> Products > Organic Intermediates > Pharmaceutical Intermediates > CAS DataBase Listed 5 > CAS 57808-66-9
57808-66-9 structure 3D

CAS 57808-66-9 AKOS005004565 products price,suppliers

  • Domperidone is a dopamine blocker and an antidopaminergic reagent.Target: Dopamine ReceptorDomperidone is a useful alternative to metoclopramide for treatment of gastroparesis due to better tolerability. Effectiveness and side-effects from domperidone may be influenced by patient-related factors including polymorphisms in genes encoding drug-metabolizing enzymes, drug transporters, and domperidone targets [1]. Domperidone is a dopamine D(2) receptor antagonist, which has been used as ant
  • Name: AKOS005004565
  • Molecular Weight: 425.917
  • Formula: C19H21NO3
  • Synonyms: 1H-Benzimidazol-2-ol, 5-chloro-1-[1-[3-(2-hydroxy-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-; 2H-Benzimidazol-2-one, 5-chloro-1-[1-[3-(2,3-dihydro-2-oxo-1H-benzimidazol-1-yl)propyl]-4-piperidinyl]-1,3-dihydro-; 5-Chloro-1-[1-[3-(2-oxo-1-benzimidazolyl)propyl]-4-piperidyl]benzimidazol-2-one; 5-Chloro-1-{1-[3-(2-hydroxy-1H-benzimidazol-1-yl)propyl]-4-piperidinyl}-1H-benzimidazol-2-ol; 5-chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propyl]piperidin-4-yl}-2,3-dihydro-1H-1,3-benzodiazol-2-one; 5-Chloro-1-{1-[3-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)propyl]-4-piperidinyl}-1,3-dihydro-2H-benzimidazol-2-one;
Properties Safety and Handling MSDS NMR Spectrum Computational chemical data
Identification
  • Cas NO.:57808-66-9
  • CID:3151
  • Name:
  • AKOS005004565 (Related Reference)
  • InChI:
  • InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30)
  • This structure is also available as a 2d Mol file
Safety Data
  • [Risk Codes]
  • R62:Possible risk of impaired fertility
  • R63:Possible risk of harm to the unborn child
  • [Safety Statements]
  • S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
  • S36:Wear suitable protective clothing
Properties
  • Molecular Weight:
  • 425.917
  • Melting Point:
  • 242.5 oC
  • Storage Temperature:
  • Store at RT
  • Refractive index:
  • 1.5400 (estimate)
  • Solubility:
  • DMSO: >10?mg/mL
  • Stability:
  • Stable. Incompatible with strong oxidizing agents.
  • More Properties>>
Question & Answer
  • What is Domperidone?Pharmacodynamics,Uses,Side effects,Precautions Domperidone is a specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms. Pharmacodynamics Domperidone is a specific blocker of dopamine receptors. It speeds gastrointestinal...more+ Jan 09 2020
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Domperidone
Domperidone
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  • Description:Product Description Morphine (domperidone tablets), which entered China in 1989, has been focusing on the domestic digestive health field for nearly 30 years. Commodity code: A19812294431, produced by Xi'an Janssen Pharmaceutical Co., Ltd., approval number: Gu...
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  • Description:Name: Domperidone Synonyms: 5-Chloro-1-(1-(3-(2-oxo-1-benzimidazolinyl)propyl)-4-piperidyl)-2-benzimidazolinone;Domperidonum;Motilium; CAS Registry number: 57808-66-9 EINECS:260-968-7 Molecular Formula: C 22 H 24 Cl N 5 O 2 Density: 1.341 g/cm 3 Water:DMSO: ...
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DOMPERIDONE BASE 99%
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  • Description:Domperidone is a specific blocker of dopamine receptors. It speeds gastrointestinal peristalsis, causes prolactin release, and is used as antiemetic and tool in the study of dopaminergic mechanisms.
  • Updatetime:May 27 2022 
Domperidone
Domperidone
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Pharmaceutical Intermediates Domperidone Medication For Lactation 57808-66-9
Pharmaceutical Intermediates Domperidone Medication For Lact...
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