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Home> Products > Pharmaceuticals and Biochemicals > Gastrointestinal Agents > CAS DataBase Listed 7 > CAS 70374-39-9
70374-39-9 structure

CAS 70374-39-9 Lornoxicam products price,suppliers

  • Lornoxicam, a COX-1 and COX-2 inhibitor, is a new nonsteroidal anti-inflammatory drug (NSAID).Target: COXLornoxicam showed a balanced inhibition of COX-1/-2 exhibiting the lowest IC50 (0.005 microM/0.008 microM) of the large panel of NSAIDs tested. lornoxicam showed a marked inhibition of IL-6 formation (IC50 54 microM) while the formation ofTNF-alpha, IL-1beta and IL-8 was only moderately affected [1]. Lornoxicam is effective in the treatment of patients with activated osteoarthritis; t

    Lornoxicam is a thienothiazine-derived monocarboxylic acid amide obtained by formal condensation of the carboxy group of 6-chloro-4-hydroxy-2-methylthieno[2,3-e][1,2]thiazine-3-carboxylic acid 1,1-dioxide with the amino group of 2-aminopyridine. Used for the treatment of pain, primarily resulting from inflammatory diseases of the joints, osteoarthritis, surgery, sciatica and other inflammations. It has a role as a non-steroidal anti-inflammatory drug, a non-narcotic analgesic and an antipyretic. It is a thienothiazine, a member of pyridines, a monocarboxylic acid amide, an organochlorine compound and a heteroaryl hydroxy compound.|Lornoxicam (chlortenoxicam) is a new nonsteroidal anti-inflammatory drug (NSAID) of the oxicam class with analgesic, anti-inflammatory and antipyretic properties. Lornoxicam differs from other oxicam compounds in its potent inhibition of prostaglandin biosynthesis, a property that explains the particularly pronounced efficacy of the drug. Lornoxicam is approved for use in Japan.|Lornoxicam is an orally bioavailable oxicam and non-steroidal anti-inflammatory drug (NSAID), with analgesic, anti-pyretic, anti-thrombotic and anti-inflammatory activities. Upon oral administration, lornoxicam binds to and inhibits the activity of the cyclooxygenase enzymes (COX) type 1 (COX-1) and type 2 (COX-2). This blocks COX-mediated signaling pathways, which leads to reduced prostaglandin and thromboxane production and decreased pain, fever and inflammation.

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  • Name: Lornoxicam
  • Molecular Weight: 371.8192
  • Formula: C13H10ClN3O4S2
  • Synonyms: 2H-Thieno(2,3-e)-1,2-thiazine-3-carboxamide, 6-chloro-4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide; 2H-Thieno[2,3-e]-1,2-thiazine-3-carboxamide, 6-chloro-4-hydroxy-2-methyl-N-2-pyridinyl-, 1,1-dioxide; 6-Chloro-4-hydroxy-2-methyl-N-2-pyridinyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-dioxide; Chlortenoxicam; Fulactive; Lofecam;
Properties Safety and Handling MSDS NMR Spectrum Computational chemical data
  • Cas NO.:70374-39-9
  • CID:54690031
  • Name:
  • Lornoxicam (Related Reference)
  • 1308068-626-2
  • InChI:
  • InChI=1S/C13H10ClN3O4S2/c1-17-10(13(19)16-9-4-2-3-5-15-9)11(18)12-7(23(17,20)21)6-8(14)22-12/h2-6,18H,1H3,(H,15,16,19)
Safety Data
  • [Risk Codes]
  • R36/37/38:Irritating to eyes, respiratory system and skin
  • [Safety Statements]
  • Hazard Symbols:
  • HazardClass:IRRITANT
  • Molecular Weight:
  • 371.8192
  • Density:
  • 1.727
  • Melting Point:
  • 225-230°C (dec.)
  • Storage Temperature:
  • -20°C Freezer
  • Refractive index:
  • 1.741
  • Solubility:
  • DMSO: >5mg/mL (warmed)
  • More Properties>>
There are 271 suppliers who can provide Lornoxicam with CAS No. 70374-39-9
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CAS 70374-39-9,Lornoxicam,99%
CAS 70374-39-9,Lornoxicam,99%
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  • Description:APIs;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals;Sulfur & selenium Compounds;Fused Ring Systems.Cyclooxygenase inhibitor; structurally similar to tenoxicam. Anti-inflammatory; analgesic Appearance: Crystalline Solid Molecular Weight: 371.82 Densi...
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High Purity CAS 70374-39-9 Lornoxicam
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Factory Supply Lornoxicam
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  • Description:CAS No.:70374-39-9;Name:Lornoxicam;Assay:97%.;appearance:Pale yellow crystalline powder;Brief Introduction:intermediates, drug discovery
  • Updatetime:Apr 23 2023 
Lornoxicam manufacture
Lornoxicam manufacture
  • Appearance:Yellow crystalline powder 
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high quality with best price 	Lornoxicam in stock CAS 	70374-39-9
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CAS 70374-39-9 Lornoxicam On Sale
CAS 70374-39-9 Lornoxicam On Sale
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Lornoxicam CAS.70374-39-9
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  • Usage:The synthesis of prostaglandins was inhibited by blocking cyclic oxygenase. 
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  • Description:Quick Details Classification: Pharmaceutical Intermediates Cas NO.:70374-39-9 Name:Lornoxicam Formula:C24H36O5 Boiling Point:
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Chlortenoxicam Anti Inflammatory Medications CAS 70374-39-9 Lornoxicam Yellow Powders
Chlortenoxicam Anti Inflammatory Medications CAS 70374-39-9 ...
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  • Description:Chlortenoxicam Anti Inflammatory Medications CAS 70374-39-9 Lornoxicam Yellow Powders Product Name: Lornoxicam Synonyms: LORNOXICAM;AKOS 93662;6-CHLORO-4-HYDROXY-2-METHYL-N-2-PYRIDINYL-2H-THIENO[2,3-E]-1,2-THIAZINE-3-CARBOXAMIDE 1,1-DIOXIDE;2h-thieno(2,3-e)-1,...
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Hot sell High Quality Lornoxicam (CAS 70374-39-9)
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High Quality Lornoxicam Powder CAS 70374-39-9
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  • Description:Quick Details ProName: Good quality Lornoxicam 99%min at best... CasNo: 70374-39-9 Molecular Formula: C13H10ClN3O4S2 Appearance: white powder Application: used as medicine intermediates. DeliveryTime: shipment within 7-10 working days afte... PackAge: custom-m...
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  • Usage:Cyclooxygenase inhibitor; structurally similar to tenoxicam. Anti-inflammatory; analgesic 
  • Description:MF: C 13 H 10 ClN 3 O 4 S 2 MW: 371.5 CAS: 70374-39-9 APPEARANCE: yellow crystalline powder ASSAY: ≥99% Safety Information
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