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Home> Products > Organic Intermediates > Organic Intermediate > CAS DataBase Listed 7 > CAS 77-86-1
77-86-1 structure

CAS 77-86-1 Tris Base | Products & Prices & Suppliers

  • Trometamol is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. Trometamol is an effective amine compound for pH control in the physiological range[1].


    Liquid


    Tris is a primary amino compound that is tert-butylamine in which one hydrogen attached to each methyl group is replaced by a hydroxy group. A compound widely used as a biological buffer substance in the pH range 7--9; pKa = 8.3 at 20 ℃; pKa = 7.82 at 37 ℃. It has a role as a buffer. It is a triol and a primary amino compound. It is a conjugate base of a member of Htris.|An organic amine proton acceptor. It is used in the synthesis of surface-active agents and pharmaceuticals; as an emulsifying agent for cosmetic creams and lotions, mineral oil and paraffin wax emulsions, as a biological buffer, and used as an alkalizer. (From Merck, 11th ed; Martindale, The Extra Pharmacopoeia, 30th ed, p1424)

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  • Name: Tris Base
  • Molecular Weight: 121.13500
  • Formula: C4H11NO3
  • Synonyms: 1-[ethyl(hydroxymethyl)amino]ethane-1,2-diol; 8VTE 1L; MFCD00004679; OmniPur TRIS -CAS 77-86-1 - Calbiochem; Pehanorm; riladyl;
Properties Safety and Handling MSDS NMR Spectrum Synthesis Route Precursor and Product Computational chemical data
Identification
Safety Data
  • [Risk Codes]
  • R36/37/38:Irritating to eyes, respiratory system and skin
  • [Safety Statements]
  • Hazard Symbols:
  • HazardClass:IRRITANT
Properties
  • Molecular Weight:
  • 121.13500
  • Density:
  • 1,353 g/cm3
  • Boiling Point:
  • 219-220°C10mm Hg(lit.)
  • Melting Point:
  • 167-172°C(lit.)
  • Flash Point:
  • 219-220°C/10mm
  • Storage Temperature:
  • 20-25°C
  • Refractive index:
  • 1.531
  • Solubility:
  • H2O: 550 g/L (25 oC)
  • Stability:
  • Stable. Incompatible with bases, strong oxidizing agents. Protect from moisture.
  • More Properties>>
Question & Answer
Upstream Product Downtream information
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Tris Base
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  • Description:Name: Trometamol Synonyms: TRS; 1gng; 1h4n; TRIS; THAM; s4176; T6977; A0321; D00396; C07182; M02623; Tham-E; Trizma; thamset; riladyl; 8VTE 1L; TRISMAT; NSC6365; AM90366; Tribase; DB03754; NE10342; 77-86-1; RP19408; SC-44694; W-104296; GTPL7328; J-610076; Tril...
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  • Description:Product Description Density 1.3±0.1 g/cm3 Boiling Point 357.0±37.0 °C at 760 mmHg Melting Point 167-172 °C(lit.) Molecular Formula C4H11NO3 Molecular Weight 121.135 Flash Point 169.7±26.5 °C Exact Mass 121.073891 PSA 86.71000 LogP -1.38
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CAS77-86-1	Trometamol
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  • Description:Trometamol is a biologically inert amino alcohol of low toxicity, which buffers carbon dioxide and acids in vitro and in vivo. Trometamol is an effective amine compound for pH control in the physiological range[1].
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