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| Chemical Name | Vanillin |
| CAS Registry Number | 121-33-5 |
| PubChemID | 1183 |
| Molecular Weight | 152.14732 |
| PSA | 46.53000 |
| LogP | 1.21330 |
| EINECS | 204-465-2 |
| Molecular Formula | C8H8O3 |
Hazard Codes: 
Xn,Xi
Risk Statements:?22-36/37/38
22:?Harmful if swallowed
36/37/38:?Irritating to eyes, respiratory system and skin
Safety Statements:?24/25-22-37/39-26
24/25:?Avoid contact with skin and eyes?
22: Do not breathe dust?
37/39:?Wear suitable gloves and eye/face protection?
26:?In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
WGK Germany:? 1
RTECS: YW5775000
HS Code: 29124100
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LDLo | intravenous | 1320mg/kg (1320mg/kg) | VASCULAR: BP LOWERING NOT CHARACTERIZED IN AUTONOMIC SECTION VASCULAR: ACUTE ARTERIAL OCCLUSION LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES |
Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 236, Pg. 2549, 1953. |
| guinea pig | LD50 | oral | 1400mg/kg (1400mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) | Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964. |
| mouse | LC | inhalation | > 41700ug/kg/2 (41.7mg/kg) | ? | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(6), Pg. 78, 1980. |
| mouse | LD50 | intraperitoneal | 475mg/kg (475mg/kg) | ? | FAO Nutrition Meetings Report Series. Vol. 44A, Pg. 78, 1967. |
| mouse | LD50 | oral | 3925mg/kg (3925mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: COMA |
National Technical Information Service. Vol. OTS0536271, |
| rabbit | LD50 | skin | > 5010mg/kg (5010mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) GASTROINTESTINAL: PERITONITIS BEHAVIORAL: FOOD INTAKE (ANIMAL) |
National Technical Information Service. Vol. OTS0533712, |
| rabbit | LDLo | oral | 3gm/kg (3000mg/kg) | ? | Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 29, Pg. 425, 1940. |
| rat | LC | inhalation | > 41700ug/kg/4 (41.7mg/kg) | ? | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 45(6), Pg. 78, 1980. |
| rat | LD | skin | > 2gm/kg (2000mg/kg) | LIVER: "JAUNDICE, OTHER OR UNCLASSIFIED" | National Technical Information Service. Vol. OTS0536272, |
| rat | LD50 | intraperitoneal | 1160mg/kg (1160mg/kg) | ? | Comptes Rendus Hebdomadaires des Seances, Academie des Sciences. Vol. 243, Pg. 609, 1956. |
| rat | LD50 | oral | 1580mg/kg (1580mg/kg) | BEHAVIORAL: COMA | Food and Cosmetics Toxicology. Vol. 2, Pg. 327, 1964. |
| rat | LD50 | subcutaneous | 1500mg/kg (1500mg/kg) | SENSE ORGANS AND SPECIAL SENSES: MIOSIS (PUPILLARY CONSTRICTION): EYE BEHAVIORAL: MUSCLE WEAKNESS LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION |
Revue Medicale de la Suisse Romande. Vol. 16, Pg. 449, 1896. |
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. Dangerous fire hazard in the form of dust when exposed to heat or flame.
Extinguishing Media: In case of fire, use water, dry chemical, chemical foam, or alcohol-resistant foam.?
Handling: Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage: Store in a cool, dry place. Store in a tightly closed container. Store under an inert atmosphere.
-114YR
