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Current Position: Home > Dictionary EN > A > 61336-70-7

61336-70-7

Chemical Name Amoxicillin trihydrate
CAS Registry Number 61336-70-7
PubChemID 62883
Molecular Weight 419.449
PSA 185.95000
LogP 0.85990
EINECS 612-127-4
Molecular Formula C16H25N3O8S
Aliases
 
61336-70-7 Properties
Density 1.54
Boiling Point 743.2 °C at 760 mmHg Vapour
Flash Point 403.3 °C
Melting Point >200°C (dec.)
Appearance A White CRYSTALLINE powder
Refractive Index 302 ° (C=0.1, H2O)
Solubility 1 G SOL IN ABOUT 370 ML WATER, ABOUT 2000 ML ALC, ABOUT 290 ML PHOSPHATE BUFFER (1%, PH 7), ABOUT 330 ML METHANOL
HS Code 29411000
Storage temp 2-8°C
Spectral properties SPECIFIC OPTICAL ROTATION: +248 DEG TO +268 DEG
 
61336-70-7 Safety Infomation
Safety Statements S36
Risk Statements R42/43
Hazard Codes Xn
Safety

Hazard Codes of Amoxycillin trihydrate (CAS NO.61336-70-7):?HarmfulXn,IrritantXi
Risk Statements: 42/43
42/43: May cause sensitization by inhalation and skin contact??
Safety Statements: 36-36/37-22
36:Wear suitable protective clothing
36/37: Wear suitable protective clothing and gloves
22: Do not breathe dust???
RTECS: XH8300000

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 3590mg/kg (3590mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 3040, 1973.
mouse LD50 oral > 25gm/kg (25000mg/kg) ? Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 3040, 1973.
mouse LD50 subcutaneous > 20gm/kg (20000mg/kg) ? Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 3040, 1973.
rabbit LD50 oral > 12500mg/kg (12500mg/kg) ? Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 3040, 1973.
rat LD50 intraperitoneal 2870mg/kg (2870mg/kg) BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX)
BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)
Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 3040, 1973.
rat LD50 oral > 15gm/kg (15000mg/kg) ? Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 3040, 1973.
rat LD50 subcutaneous > 8gm/kg (8000mg/kg) ? Kiso to Rinsho. Clinical Report. Vol. 7, Pg. 3040, 1973.

Formulations/Preparations AMOXICILLIN (AMOXIL, LAROTID) IS AVAILABLE FOR ORAL USE IN CAPSULES (250 OR 500 MG), AS ORAL SUSPENSION (125 OR 250 MG/5 ML), & AS PEDIATRIC DROPS (50 MG/ML).
Exposure Standards and Regulations Manufacturers, packers, and distributors of drug and drug products for human use are responsible for complying with the labeling, certification, and usage requirements as prescribed by the Federal Food, Drug, and Cosmetic Act, as amended (secs 201-902, 52 Stat. 1040 et seq., as amended; 21 U.S.C. 321-392).
Specification

?Amoxycillin trihydrate , its cas register number is 61336-70-7. It also can be called 4-Acetamido-2-ethoxybenzoesaeuremethylester ; and 6-[2-Amino-2-(4-hydroxyphenyl)-acetyl]amino-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid trihydrate .

Disposal Methods SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
 
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