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Current Position: Home > Dictionary EN > P > 9003-39-8

Povidone 9003-39-8

Chemical Name Povidone
CAS Registry Number 9003-39-8
PubChemID 6917
Molecular Weight 111.14176
PSA 20.31000
LogP 0.69020
EINECS 618-363-4
Molecular Formula C6H9NO
 
9003-39-8 Properties
Density 1.144
Boiling Point 217.6 °C at 760 mmHg
Flash Point 93.9 °C
Melting Point 130℃
Appearance White powder.
Vapour 1.1X10-11 mm Hg @ 25 °C /Estimated/
Refractive Index Index of refraction = 1.511 @ 25 °C/D
Solubility 10g/100mL at 2 °C
Color/Form Faintly yellow solid
WHITE TO CREAMY WHITE POWDER
White, free-flowing, amorphous powder or aqueous solution
Stability Stable. Incompatible with strong oxidizing agents. Light sensitive. Hygroscopic.
HS Code 39059990
Storage temp Store at RT.
Spectral properties SPECTROSCOPY DATA: INFRA-RED CARBONYL BAND AT 1680 CM X 10-1
 
9003-39-8 Safety Infomation
Safety Statements S24/25
Safety

Suspected carcinogen with experimental neoplastigenic data. When heated to decomposition it emits toxic fumes of NOx.
The Safety Statements information of? Povidone (CAS NO.9003-39-8):
22:? Do not breathe dust?
24/25:? Avoid contact with skin and eyes?
WGK Germany: 1
RTECS:?TR8370000
HS Code:?39059990

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
guinea pig LD50 oral 100gm/kg (100000mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 486, 1974.
mouse LD50 intraperitoneal 12gm/kg (12000mg/kg) ? FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 486, 1974.
mouse LD50 oral > 40gm/kg (40000mg/kg) ? FAO Nutrition Meetings Report Series. Vol. 40, Pg. 164, 1967.
mouse LD50 unreported 16gm/kg (16000mg/kg) ? Khimiko-Farmatsevticheskii Zhurnal. Chemical Pharmaceutical Journal. For English translation, see PCJOAU. Vol. 19, Pg. 212, 1985.
mouse LDLo oral 3gm/kg (3000mg/kg) ? Biomaterials, Medical Devices, and Artificial Organs. Vol. 12, Pg. 1, 1984.
mouse LDLo oral 3gm/kg (3000mg/kg) ? Biomaterials, Medical Devices, and Artificial Organs. Vol. 12, Pg. 1, 1984.
mouse LDLo oral 5gm/kg (5000mg/kg) ? Biomaterials, Medical Devices, and Artificial Organs. Vol. 12, Pg. 1, 1984.
rabbit LD50 oral 1040mg/kg (1040mg/kg) ? Veterinariya. Veterinary Science. Vol. 61(12), Pg. 68, 1985.
rat LD50 oral 100gm/kg (100000mg/kg) GASTROINTESTINAL: "HYPERMOTILITY, DIARRHEA" FAO Nutrition Meetings Report Series. Vol. 53A, Pg. 486, 1974.

Sensitive Hygroscopic
Fire Potential ... Compatible with wide range of hydrophilic and hydrophobic resins.
Formulations/Preparations ...AVAILABLE IN US AS COMMERCIAL &...(USP) GRADES. THERE ARE 4 COMMERCIAL VISCOSITY GRADES, CONTAINING A MAX OF 1% RESIDUAL, UNREACTED MONOMER AS N-VINYL-2-PYRROLIDONE & 0.02% ASH (ON A DRY BASIS). POWDERED FORMS CONTAIN A MAX OF 5% WATER, & AQUEOUS SOLUTIONS CONTAIN 55-80% WATER.
USP GRADE POLYVINYL PYRROLIDONE CONTAINS 12-13% NITROGEN ON AN ANHYDROUS BASIS AND A MAXIMUM OF 0.00015% ARSENIC, 0.001% LEAD, 0.5% ALDEHYDE (AS ACETALDEHYDE) AND 1% UNREACTED N-VINYL-2-PYRROLIDONE.
A HIGH-MOLECULAR-WEIGHT CROSS-LINKED GRADE OF POLYVINYL PYRROLIDONE, WHICH IS INSOLUBLE IN WATER, IS AVAILABLE AS A POWDER CONTAINING LESS THAN 5% WATER.
Specification

? Povidone , with CAS number of 9003-39-8, can be called Povidone/Polyvinylpyrrolidone(PVP) ; PVP 3000 ; N-Vinylpyrrolidone polymer ; N-Vinylbutyrolactam polymer ; N-Vinylpyrrolidone homopolymer ; N-Vinyl-2-pyrrolidone polymer ; N-Vinyl-2-pyrrolidinone homopolymer .

Report

IARC Cancer Review: Animal Limited Evidence IMEMDT ?? IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 19 ,1979,p. 461.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.:?) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) .

Disposal Methods SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
 
 
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