1-Bromo-2,4-difluorobenzene

1-Bromo-2,4-difluoro 1-bromo-2,4-difluoro-benzene 2,4-diFC6H3Br 2,4-Difluoro 2,4-Difluoro-1-bromobenzene 2,4-DIFLUOROBROMOBENZENE 2,4-Difluorophenyl bromide 4-Bromo-1,3-difluorobenzene Benzene, 1-bromo-2,4-difluoro- Benzene,1-bromo-2,4-difluoro Bromo-2,4-difluorobenzene EINECS 206-479-4 FR CF DE MFCD00000330

The 1-Bromo-2,4-difluorobenzene?with cas registry number of 348-57-2 is also?known as?2,4-Difluorobromobenzene. It is a kind of clear colorless to brown liquid which has the EINECS?registry number of 206-479-4.?Both its systematic name and IUPAC name are the same which is called 1-bromo-2,4-difluorobenzene. This chemical belongs to the several?categories: Other fluorin-contained compounds; Aromatic Hydrocarbons (substituted) & Derivatives; Miscellaneous; Bromine Compounds; Fluorine Compounds; Aryl; C6; Halogenated Hydrocarbons.

The physical properties about this chemical are:?(1)ACD/LogP: 2.98; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.98; (4)ACD/LogD (pH 7.4): 2.98; (5)ACD/BCF (pH 5.5): 108.08; (6)ACD/BCF (pH 7.4): 108.08; (7)ACD/KOC (pH 5.5): 993.93; (8)ACD/KOC (pH 7.4): 993.93; (9)#H bond acceptors: 0; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 0; (12)Index of Refraction: 1.506; (13)Molar Refractivity: 33.93 cm³; (14)Molar Volume: 114 cm³; (15)Surface Tension: 32.3 dyne/cm; (16)Density: 1.692 g/cm³; (17)Flash Point: 51.7 °C; (18)Enthalpy of Vaporization: 36.94 kJ/mol; (19)Boiling Point: 148.4 °C at 760 mmHg; (20)Vapour Pressure: 5.38 mmHg at 25°C ; (21)Refractive index: n20/D 1.505(lit.).

Preparation of? 1-Bromo-2,4-difluorobenzene:?it can be made by 2,4-Difluorophenyltrimethylsilane with?reagent Br₂ at?temperature of 80 ℃. The reaction time is 3 hours. And the yield is 38%.

Uses of? 1-Bromo-2,4-difluorobenzene: this chemical can react with?benzaldehyde to produce?2,4-Difluorobenzhydrol?by using reagent n-BuLi and solvent hexane, diethyl ether at -78 Deg C for 30 min. The?yield is about 66%.

When you are using this chemical, please be cautious about it as the following:
This chemical is irritating to eyes, respiratory system. Therefore, wear suitable protective clothing, gloves and eye/face protection during using it. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Keep away from sources of ignition - No smoking for it is flammable.

In addition, you could convert the following datas into the molecular structure:
(1)SMILES: Fc1ccc(Br)c(F)c1;
(2)InChI: InChI=1/C6H3BrF2/c7-5-2-1-4(8)3-6(5)9/h1-3H;
(3)InChIKey: MGHBDQZXPCTTIH-UHFFFAOYAK