2,6-Difluoroaniline

Iupac Name：2,6-difluoroaniline

Molecular Weight：129.107406

Modify Date.: 2022-11-29 05:26

Introduction: 2,6-Difluoroaniline is an important chemical in the sythesis technology for high-efficiency insecticide. 2,6-Difluoroaniline Preparation Products And Raw materials Raw materials View more+

Request For Quotation

1. Names and Identifiers

1.1 Name: 2,6-Difluoroaniline
1.2 Synonyms: 2,6-DIFLUOROBENZENAMINE 2,6-Difluorobenzeneamine 2,6-Difluorophenylamine Aniline, 2,6-difluoro- Benzenamine, 2,6-difluoro- NSC 127234

1.3 CAS No.: 5509-65-9

1.4 CID: 79647

1.5 EINECS(EC#): 226-853-0

1.6 Molecular Formula: C6H5F2N (isomer)

1.7 Inchi: InChI=1S/C6H5F2N/c7-4-2-1-3-5(8)6(4)9/h1-3H,9H2

1.8 InChkey: ODUZJBKKYBQIBX-UHFFFAOYSA-N

1.9 Canonical Smiles: C1=CC(=C(C(=C1)F)N)F

1.10 Isomers Smiles: C1=CC(=C(C(=C1)F)N)F

2. Properties

2.1 Density: 1.199

2.1 Melting point: 144-148C

2.1 Boiling point: 51-52℃ (15 mmHg)

2.1 Refractive index: n20/D 1.508(lit.)

2.1 Flash Point: 43℃

2.1 Precise Quality: 129.03900

2.1 PSA: 26.02000

2.1 logP: 2.12820

2.1 Appearance: clear,colorless liquid

2.2 Storage: Ambient temperatures.

2.3 Chemical Properties: clear yellow to brown liquid

2.4 Color/Form: Clear yellow to brown

2.5 pKa: 1.81±0.10(Predicted)

2.6 Water Solubility: Slightly soluble in water.

2.7 Stability: Stable at room temperature in closed containers under normal storage and handling conditions.

2.8 StorageTemp: Flammables area

3. Use and Manufacturing

3.1 Usage: 2,6-Difluoroaniline is an important chemical in the sythesis technology for high-efficiency insecticide. 2,6-Difluoroaniline Preparation Products And Raw materials Raw materials

4. Safety and Handling

4.1 Symbol: GHS02;GHS07;

4.1 Hazard Codes: Xn

4.1 Signal Word: Warning

4.1 Risk Statements: R10;R20/21/22;R36/37/38

4.1 Safety Statements: S16;S23;S26;S36/37/39

4.1 Packing Group: III

4.1 Hazard Class: 3

4.1 Hazard Declaration: H226; H302 + H312 + H332; H317

4.1 RIDADR: UN 1993

4.1 Caution Statement: P280

4.1 WGK Germany: 3

5. MSDS

2.Hazard identification

2.1 Classification of the substance or mixture

Flammable liquids, Category 3

Acute toxicity - Oral, Category 4

Acute toxicity - Dermal, Category 4

Skin irritation, Category 2

Eye irritation, Category 2

Acute toxicity - Inhalation, Category 4

Specific target organ toxicity \u2013 single exposure, Category 3

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word	Warning
Hazard statement(s)	H226 Flammable liquid and vapour H302 Harmful if swallowed H312 Harmful in contact with skin H332 Harmful if inhaled
Precautionary statement(s)
Prevention	P210 Keep away from heat, hot surfaces, sparks, open flames and other ignition sources. No smoking. P233 Keep container tightly closed. P240 Ground and bond container and receiving equipment. P241 Use explosion-proof [electrical/ventilating/lighting/...] equipment. P242 Use non-sparking tools. P243 Take action to prevent static discharges. P280 Wear protective gloves/protective clothing/eye protection/face protection. P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P303+P361+P353 IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water [or shower]. P370+P378 In case of fire: Use ... to extinguish. P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/\u2026if you feel unwell. P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P312 Call a POISON CENTER/doctor/\u2026if you feel unwell. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. P332+P313 If skin irritation occurs: Get medical advice/attention. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313 If eye irritation persists: Get medical advice/attention. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.
Storage	P403+P235 Store in a well-ventilated place. Keep cool. P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

View all

6. NMR Spectrum

13C NMR : Predict

1H NMR : 400 MHz in CDCl3

1H NMR : Predict

Predict 1H proton NMR

IR : liquid film

Mass

Mass spectrum (electron ionization)

7. Synthesis Route

5509-65-9Total: 8 Synthesis Route

87-61-6 55 Suppliers

5509-65-9 272 Suppliers

Literatures:
Journal of Fluorine Chemistry, , vol. 53, # 3 p. 379 - 386
Yield: null

87-61-6 55 Suppliers

4519-40-8 153 Suppliers

5509-65-9 272 Suppliers

Literatures:
Journal of Fluorine Chemistry, , vol. 53, # 3 p. 379 - 386
Yield: null

372-39-4 227 Suppliers

5509-65-9 272 Suppliers

Literatures:
US5294742 A1, ;
Yield: ~79%

View all

8. Precursor and Product

precursor:

372-18-9

108-70-3

385-00-2

87-61-6

1435-43-4

38361-37-4

372-39-4

product :

196403-27-7

103943-13-1

3896-29-5

13697-89-7

174844-42-9

1033225-44-3

102284-85-5

29270-54-0

29270-56-2

67567-26-4

383199-90-4

123843-67-4

19064-24-5

811799-69-6

207974-17-2

383199-91-5

19064-25-6

62256-29-5

383199-89-1

69411-06-9

456-49-5

80829-40-9

141743-49-9

64248-56-2

View all

9. Other Information

9.0 Usage: 2,6-Difluoroaniline is an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

10. Computational chemical data

Molecular Weight: 129.107406g/mol
Molecular Formula: C₆H₅F₂N
Compound Is Canonicalized: True
XLogP3-AA: 1.4
Exact Mass: 129.03900549
Monoisotopic Mass: 129.03900549
Complexity: 87.1
Rotatable Bond Count: 0
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 3
Topological Polar Surface Area: 26
Heavy Atom Count: 9
Defined Atom Stereocenter Count: 0
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Isotope Atom Count: 0
Covalently-Bonded Unit Count: 1
CACTVS Substructure Key Fingerprint: AAADcYBiAYAAAAAAAAAAAAAAAAAAAAAAAAAwAAAAAAAAAAABAAAAHQAQAAAACAiBEAgwwIBAAACAACRCQACCAAAgAAAIiAAARIgIICKAkZGAIABggAAIyAcQAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA==

11. Recommended Suppliers

Global266SuppliersView all >>

Wuhan Fortuna Chemical Co., Ltd. Diamond member

10YRS

Products:API,fine chemical&its intermediates,biological chemistry
Tel:0086-27-59207850
Email:info@fortunachem.com

2,6-Difluoroaniline CAS 5509-65-9

Purity:99%Packing: 200kg/bag FOB
Price: 10 USD/kg
Time: 2023/05/29

Inquire

Hebei Yanxi Chemical Co.,Ltd Diamond member

5YRS

Products:Division I, the main production Lead acetate phenylacetamide Cyromazine quality is very good!
Tel:86-185-31123677
Email:xing@yan-xi.com

2,6-Difluoroaniline

Purity:99%Packing: 200kg/bag FOB
Price: 1 USD/kilogram
Time: 2023/05/11

Inquire

Amitychem Corporation Diamond member

3YRS

Products:Manufacture & Supply Biopharm Chemical, Specialty Chemical, PetroChemical.
Tel:86-592-8883942
Email:sale@amitychem.com

Factory Supply 2,6-Difluorobenzeneamine

Purity:99%Packing: 200kg/bag FOB
Price: 0.1 USD/kilogram
Time: 2023/03/01

Inquire

Dayang Chem (Hangzhou) Co., Ltd. Diamond member

12YRS

Products:Chemical products
Tel:86-571-88938639
Email:sales-gc@dycnchem.com

2,6-Difluoroaniline

Purity:99%Packing: 200kg/bag FOB
Price: 1 USD/kilogram
Time: 2023/04/23

Inquire

Jinlan Pharm-Drugs Technology Co., Limited Diamond member

10YRS

Products:Veterinary products,Nutrition products,Agrochemicals,Active pharmaceutical Ingredients,Custom systhesis,Contract manufacturing
Tel:86-571-85829052
Email:market@royalpharms.com

2,6-Difluoroaniline

Purity:99%Packing: 200kg/bag FOB
Price: 100 USD/kilogram
Time: 2023/03/14

Inquire

12. Realated Product Infomation

367-25-9 2,4-Difluoroaniline

372-39-4 3,5-Difluoroaniline

3863-11-4 3,4-Difluoroaniline

4519-40-8 2,3-Difluoroaniline

367-30-6 2,5-Difluoroaniline

76563-56-9 2,4-DIFLUOROANILINE

67567-26-4 4-Bromo-2,6-difluoroaniline

Recently Updated : 149505-86-2 1824189-94-7 114554-08-4 79583-58-7 1368226-38-3 1314933-74-8 3694-84-6 1097789-12-2 172649-59-1 2089678-03-3