2-Amino-5-chloropyridine
- Iupac Name：5-chloropyridin-2-amine
- CAS No.: 1072-98-6
- Molecular Weight：128.5596
- Modify Date.: 2023-03-06 09:35
- Introduction: Production of herbicides, zopiclone, and organic synthesis.
View more+
1. Names and Identifiers
- 1.1 Name
- 2-Amino-5-chloropyridine
- 1.2 Synonyms
(5-Chloropyridin-2-yl)amine 2-Amino-5-chloropyridinium 2-Pyridinamine, 5-chloro- 5-Chloro-2-aminopyridine 5-Chloro-2-pyridinamine 5-Chloro-2-pyridineamine 5-Chloro-2-pyridylamine 5-Chloro-α-aminopyridine AI3-52448 NSC 26283 Pyridine, 2-amino-5-chloro- Pyridinium, 2-amino-5-chloro- RP 26695
- 1.3 CAS No.
- 1072-98-6
- 1.4 CID
- 66174
- 1.5 EINECS(EC#)
- 214-020-4
- 1.6 Molecular Formula
- C5H5ClN2 (isomer)
- 1.7 Inchi
- InChI=1S/C5H5ClN2/c6-4-1-2-5(7)8-3-4/h1-3H,(H2,7,8)
- 1.8 InChkey
- MAXBVGJEFDMHNV-UHFFFAOYSA-N
- 1.9 Canonical Smiles
- C1=CC(=NC=C1Cl)N
- 1.10 Isomers Smiles
- C1=CC(=NC=C1Cl)N
2. Properties
- 2.1 Density
- 1.326
- 2.1 Melting point
- 134-138℃
- 2.1 Boiling point
- 127-128℃ (11 mmHg)
- 2.1 Refractive index
- 1.5110 (estimate)
- 2.1 Flash Point
- 160℃
- 2.1 Precise Quality
- 128.01400
- 2.1 PSA
- 38.91000
- 2.1 logP
- 1.89840
- 2.1 Solubility
- 1.0g/l
- 2.2 Appearance
- similar to white powder crystal
- 2.3 Storage
- Ambient temperatures.
- 2.4 Chemical Properties
- beige to beige-brown crystalline powder
- 2.5 Color/Form
- Beige to beige-brown
- 2.6 pKa
- 4.67±0.13(Predicted)
- 2.7 Water Solubility
- 1 g/L (20 oC)
- 2.8 Stability
- Stable under normal temperatures and pressures.
- 2.9 StorageTemp
- Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
3. Use and Manufacturing
- 3.1 Purification Methods
- Recrystallise this base from pet ether. It sublimes at 50o/0.5mm. [Beilstein 22 II 332, 22/8 V 541.] 2-Amino-5-chloropyridine Preparation Products And Raw materials Preparation Products
4. Safety and Handling
- 4.1 Symbol
- GHS07;
- 4.1 Hazard Codes
- Xn
- 4.1 Signal Word
- Warning
- 4.1 Risk Statements
- R22;R36/37/38
- 4.1 Safety Statements
- S26;S37/39
- 4.1 Hazard Class
- IRRITANT
- 4.1 Hazard Declaration
- H302
- 4.1 WGK Germany
- 3
5. MSDS
2.Hazard identification
2.1 Classification of the substance or mixture
Acute toxicity - Oral, Category 4
2.2 GHS label elements, including precautionary statements
| Pictogram(s) |  |
| Signal word | Warning |
| Hazard statement(s) | H302 Harmful if swallowed |
| Precautionary statement(s) | |
| Prevention | P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. |
| Response | P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/\u2026if you feel unwell. P330 Rinse mouth. |
| Storage | none |
| Disposal | P501 Dispose of contents/container to ... |
2.3 Other hazards which do not result in classification
none
7. Synthesis Route
1072-98-6Total: 13 Synthesis Route
9. Other Information
- 9.0 BRN
- 108735
- 9.1 Chemical Properties
- beige to beige-brown crystalline powder
- 9.2 Purification Methods
- Recrystallise this base from pet ether. It sublimes at 50o/0.5mm. [Beilstein 22 II 332, 22/8 V 541.]
10. Computational chemical data
- Molecular Weight: 128.5596g/mol
- Molecular Formula: C5H5ClN2
- Compound Is Canonicalized: True
- XLogP3-AA: null
- Exact Mass: 128.0141259
- Monoisotopic Mass: 128.0141259
- Complexity: 76.8
- Rotatable Bond Count: 0
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 2
- Topological Polar Surface Area: 38.9
- Heavy Atom Count: 8
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count: 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Isotope Atom Count: 0
- Covalently-Bonded Unit Count: 1
- CACTVS Substructure Key Fingerprint: AAADcYBjAAAEAAAAAAAAAAAAAAAAAAAAAAAsAAAAAAAAAAABgAAAHAIQAAAACALBEiQ9sJJIEACgADJnZACCgCkxByAI2CA4ZpiIIOLBk5HEIAhgkALIyCYQAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA==
11. Recommended Suppliers
-
- Products:chemical industry and Pharmaceutical Intermediates products
- Tel:0086-0311-888888
- Email:jessica@zhanyaobio.com
-
- Products:pmk powder ;pmk oil ;bmk powder ;bmk oil ;Protonitazene hcl ; Bromazolam ; Metonitazene; 2-Bromo-4'-methylpropiophenone ;
- Tel:+86-186-33020931
- Email:olivia@chbbest.com
-
- Products:We are engaged in the development, marketing and sales of apis, intermediates, natural products (extracts), fine chemicals, food additives, agricultural chemicals and other products.
- Tel:0086-0319-19133911216
- Email:Jany1001@chengcaibio.com
-
- Products:My whatsapp:+86 13043111536 cas no.1451-82-7,79099-07-3,5449-12-7,5337-93-9,49851-31-2,288573-56-8
- Tel:86-311-13043116031
- Email:Fan@wh-xiju.com
-
- Products:chemicals
- Tel:0311-18503114-031178503114
- Email:mandy@rilonchem.com
12. Realated Product Infomation
skype
-120YR
