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Home> Encyclopedia >Pharmaceutical Intermediates>Hormones and synthetic substitutes>Pharmaceutical
Boldenone structure
Boldenone structure

Boldenone

Iupac Name:(8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one
CAS No.: 846-48-0
Molecular Weight:286.415
Modify Date.: 2022-11-29 04:30
Introduction: Boldenone is the chemical precursor of its endecylenate ester prodrug boldenone undecylenate – which is used extensively as a steroid for animals, mainly horses and cattle, under the brand name Equipoise, among others. For this application, it is injected to improve the weight, hair coat, appetite, and general physical condition of horses affected by disease, anorexia, or overwork. It is also used as an illegal doping agent for human athletes. As a derivative of testosterone, it retains its anabolic strength, but exhibits reduced androgenic effects. View more+
1. Names and Identifiers
1.1 Name
Boldenone
1.2 Synonyms

(17b)-17-Hydroxyandrosta-1,4-dien-3-one (17Β)-17-Hydroxyandrosta-1,4-dien-3-one 1,2-didehydrotestosterone 1,4-Androstadien-17b-ol-3-one 17-beta-hydroxy-17-alpha-1,4-androstadien-3-one 17-beta-hydroxy-androsta-4-dien-3-one 17-hydroxy-10,13-dimethyl-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-3-one 1-DEHYDROTESTOSTERONE 3-Oxo-17b-hydroxy-1,4-androstadiene Androsta-1,4-dien-3-one, 17-hydroxy-, (17Β)- Androsta-1,4-dien-3-one, 17Β-hydroxy- Boldenoe BOLDENON Boldenone (eq) BOLDENONE UNDECILINATE Boldenone(846-48-0) Cuproterone Acetate D1-Testosterone dehydrotestosterone EINECS 212-686-0 MFCD00037712 Testosterone Impurity 8(Testosterone EP Impurity H) Δ1-Testosterone

1.3 CAS No.
846-48-0
1.4 CID
13308
1.5 EINECS(EC#)
212-686-0
1.6 Molecular Formula
C19H26O2 (isomer)
1.7 Inchi
InChI=1S/C19H26O2/c1-18-9-7-13(20)11-12(18)3-4-14-15-5-6-17(21)19(15,2)10-8-16(14)18/h7,9,11,14-17,21H,3-6,8,10H2,1-2H3/t14-,15-,16-,17-,18-,19-/m0/s1
1.8 InChkey
RSIHSRDYCUFFLA-DYKIIFRCSA-N
1.9 Canonical Smiles
CC12CCC3C(C1CCC2O)CCC4=CC(=O)C=CC34C
1.10 Isomers Smiles
C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@@H]2O)CCC4=CC(=O)C=C[C@]34C
2. Properties
2.1 Density
1.14
2.1 Melting point
164-166°C
2.1 Boiling point
435.6 °C at 760 mmHg
2.1 Refractive index
1.577
2.1 Flash Point
185.8 °C
2.1 Precise Quality
286.19300
2.1 PSA
37.30000
2.1 logP
3.65520
2.1 Appearance
White to off-white crystalline powder
2.2 Storage
Controlled Substance, -20°C Freezer
2.3 Chemical Properties
Crystalline Solid
2.4 pKa
15.05±0.60(Predicted)
2.5 Stability
Stable at normal temperatures and pressures.
2.6 StorageTemp
Controlled Substance, -20°C Freezer
3. Use and Manufacturing
3.1 Definition
ChEBI: An 3-oxo-Delta1,Delta4-steroid substituted by an oxo group at position 3 and a beta-hydroxy group at position 17. It is an anabolic androgenic steroid that has been eveloped for veterinary use.
3.2 GHS Classification
Signal: Danger
GHS Hazard Statements
Aggregated GHS information provided by 10 companies from 5 notifications to the ECHA C&L Inventory. Each notification may be associated with multiple companies.

H302 (20%): Harmful if swallowed [Warning Acute toxicity, oral]
H315 (20%): Causes skin irritation [Warning Skin corrosion/irritation]
H319 (20%): Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H351 (70%): Suspected of causing cancer [Warning Carcinogenicity]
H360 (70%): May damage fertility or the unborn child [Danger Reproductive toxicity]
H362 (70%): May cause harm to breast-fed children [Reproductive toxicity, effects on or via lactation]
H412 (70%): Harmful to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]

Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.

Precautionary Statement Codes
P201, P202, P260, P263, P264, P270, P273, P280, P281, P301+P312, P302+P352, P305+P351+P338, P308+P313, P321, P330, P332+P313, P337+P313, P362, P405, and P501
3.3 Usage
Boldenone is an anabolic steroid. Controlled substance.
4. Safety and Handling
4.1 Hazard Codes
F,Xn
4.1 Risk Statements
11-20/21/22-36
4.1 Safety Statements
16-36/37
4.1 Hazard Declaration
H302
4.1 Caution Statement
P201, P202, P260, P263, P264, P270, P273, P280, P281, P301+P312, P302+P352, P305+P351+P338, P308+P313, P321, P330, P332+P313, P337+P313, P362, P405, P501
4.1 RTECS
BV7994400
5. MSDS

2.Hazard identification

2.1 Classification of the substance or mixture

Carcinogenicity, Category 2

Reproductive toxicity, Category 1A

Reproductive toxicity, Additional category for effects on or via lactation

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word

Danger

Hazard statement(s)

H351 Suspected of causing cancer

H360 May damage fertility or the unborn child

H362 May cause harm to breast-fed children

H412 Harmful to aquatic life with long lasting effects

Precautionary statement(s)
Prevention

P201 Obtain special instructions before use.

P202 Do not handle until all safety precautions have been read and understood.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P263 Avoid contact during pregnancy and while nursing.

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P273 Avoid release to the environment.

Response

P308+P313 IF exposed or concerned: Get medical advice/ attention.

Storage

P405 Store locked up.

Disposal

P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

9. Other Information
9.0 Description
Boldenone is the chemical precursor of its endecylenate ester prodrug boldenone undecylenate – which is used extensively as a steroid for animals, mainly horses and cattle, under the brand name Equipoise, among others. For this application, it is injected to improve the weight, hair coat, appetite, and general physical condition of horses affected by disease, anorexia, or overwork. It is also used as an illegal doping agent for human athletes. As a derivative of testosterone, it retains its anabolic strength, but exhibits reduced androgenic effects.
9.1 Sources
https://en.wikipedia.org/wiki/Boldenone_undecylenate
https://en.wikipedia.org/wiki/Boldenone
https://www.drugs.com/vet/equipoise.html
https://www.steroidal.com/steroid-profiles/equipoise/
https://www.evolutionary.org/equipoise-boldenone-undecylenate
9.2 Description
Boldenone (Item No. 15432) is an analytical reference standard categorized as an anabolic androgenic steroid. Anabolic steroids, including boldenone, have been used to enhance physical performance in athletes. Boldenone is regulated as a Schedule III compound in the United States. This product is intended for research and forensic applications.
9.3 Chemical Properties
Crystalline Solid
9.4 Uses
Boldenone is an anabolic steroid. Controlled substance.
9.5 Uses
Controlled substance. Anabolic steroid
9.6 Definition
ChEBI: An 3-oxo-Delta1,Delta4-steroid substituted by an oxo group at position 3 and a beta-hydroxy group at position 17. It is an anabolic androgenic steroid that has been eveloped for veterinary use.
9.7 Brand name
Equipoise [Veterinary] (Fort Dodge Animal Health).
9.8 Collision Cross Section
171.76 ?2 [M+H]+
9.9 Mesh
These compounds stimulate anabolism and inhibit catabolism. They stimulate the development of muscle mass, strength, and power. (See all compounds classified as Anabolic Agents.)
9.10 Biological Half Life
14 days
9.11 Mesh Entry Terms
1,4-androstadiene-17-beta-ol-3-one
9.12 Dea Controlled Substances
Boldenone|Equipoise, Parenabol, Vebonol, dehydrotestosterone|4000|Schedule III - Substances in the DEA Schedule III have a potential for abuse less than substances in Schedules I or II and abuse may lead to moderate or low physical dependence or high psychological dependence.|No
9.13 Use Classification
Lipids -> Sterol Lipids [ST] -> Steroids [ST02] -> C19 steroids (androgens) and derivatives [ST0202]|Pharmaceuticals -> Animal Drugs -> Approved in Taiwan
10. Computational chemical data
  • Molecular Weight: 286.415g/mol
  • Molecular Formula: C19H26O2
  • Compound Is Canonicalized: True
  • XLogP3-AA: null
  • Exact Mass: 286.193280068
  • Monoisotopic Mass: 286.193280068
  • Complexity: 546
  • Rotatable Bond Count: 0
  • Hydrogen Bond Donor Count: 1
  • Hydrogen Bond Acceptor Count: 2
  • Topological Polar Surface Area: 37.3
  • Heavy Atom Count: 21
  • Defined Atom Stereocenter Count: 6
  • Undefined Atom Stereocenter Count: 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Isotope Atom Count: 0
  • Covalently-Bonded Unit Count: 1
  • CACTVS Substructure Key Fingerprint: AAADceB4MAAAAAAAAAAAAAAAAAAAAYAAAAAwYIAAAAAAAGDAAAAAGgAACAAADxSggAICAAAAAgCIAqBSAAAAAAAgAAAICAAAAEgAEAIAAQAAQAAEgAAIAYOAwPAPgAAAAAAAAACAAAQAACAAAIAADAAAAA==
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