Guidechem | China Chemical Manufacturers,suppliers,B2B Marketplace
Encyclop..
  • Products
  • Encyclopedia
  • Buy offers
  • Suppliers
Home> Encyclopedia >   /  Food Additive Products  /  Pharmaceutical Intermediates  /  Food Additives
Dimethyl sulfone structure
Dimethyl sulfone structure

Dimethyl sulfone

Iupac Name:methylsulfonylmethane
CAS No.: 67-71-0
Molecular Weight:94.13284
Modify Date.: 2022-11-25 02:15
Introduction: Dimethyl Sulfone (MSM) is an organic sulfur-containing compound that occurs naturally in a variety of fruits, vegetables, grains, and animals including humans. a white, odorless, slightly bitter-tasting crystalline substance containing 34-percent elemental sulfur, MSM is a normal oxidative metabolite product of dimethyl sulfoxide (DMSO). Cow’s milk is the most abundant source of MSM, containing approximately 3.3 parts per million (ppm). Other foods containing MSM are coffee (1.6 ppm), tomatoes (trace to 0.86 ppm), tea (0.3 ppm), Swiss chard (0.05-0.18 ppm), beer (0.18 ppm), corn (up to 0.11 ppm), and alfalfa (0.07 ppm).MSM has been isolated from plants such as Equisetum arvense, also known as horsetail.Dimethyl Sulfone has the ability to enhance the body to produce insulin, while it can promote carbohydrate metabolism. It is essential for the synthesis of human collagen. It can not only promote wound healing, but also contribute for metabolic and neurological health requirement of vitamin B and vitamin C, biotin synthesis and activation, so it is known as "naturally beautiful carbon material". Dimethyl Sulfone exists in human skin, hair, nails, bones, muscles and various organs. Once people who are lack of it will get health disorders or diseases. It is the main substance for people to maintain the balance of biological sulfur. It has therapeutic value and healthcare function for people. It is an essential drug for human survial and health protection. View more+
1. Names and Identifiers
1.1 Name
Dimethyl sulfone
1.2 Synonyms

(CH3)2SO2 DIMETHYL SULPHONE Dimethylsulfon DMSO2 EINECS 200-665-9 Methane, sulfonylbis- Methane,sulfonylbis- Methanesulfonylmethane Methyl sulfone Methyl sulfone Sulfonyl bismethane Methylsulfone METHYLSULPHONE methylsulphonylmethane MFCD00007566 MSM Sulfone, dimethyl- Sulfone,dimethyl

1.3 CAS No.
67-71-0
1.4 CID
6213
1.5 EINECS(EC#)
200-665-9
1.6 Molecular Formula
C2H6O2S (isomer)
1.7 Inchi
InChI=1S/C2H6O2S/c1-5(2,3)4/h1-2H3
1.8 InChkey
HHVIBTZHLRERCL-UHFFFAOYSA-N
1.9 Canonical Smiles
CS(=O)(=O)C
1.10 Isomers Smiles
CS(=O)(=O)C
2. Properties
3.1 Density
1,16
3.1 Melting point
107-111℃
3.1 Boiling point
238℃
3.1 Refractive index
1.4226 (20 C)
3.1 Flash Point
143℃
3.1 Precise Quality
94.00890
3.1 PSA
42.52000
3.1 logP
0.74160
3.1 Solubility
150g/l
3.2 Appearance
white crystalline flakes
3.3 Storage
Ambient temperatures.
3.4 Color/Form
White
3.5 pKa
28(at 25℃)
3.6 Water Solubility
H2O: 150 g/L (20 oC)
3.7 Stability
Stable. Combustible. Incompatible with strong oxidizing agents.
3.8 StorageTemp
Store below +30°C.
3. Use and Manufacturing
4.1 Purification Methods
Using different purification methods, the products contained different impurities. in the finished product is different purification methods are also different. In general, it is decolored by active carbon, demineralized by ion exchange, and then recrystallized the solvent, dried by vacuum. After that, it is sieved and added an antistatic agent and a slip agent, in order to meet the export requirements. There is no national or ministerial standards. Currently, the countries in the world continue to enforce corporate standards or contract specifications.
4.2 Usage

High temp solvent for many inorganic and organic substances.

4. Safety and Handling
5.1 Risk Statements
S22-S24/25
5.1 Safety Statements
S24/25
5.1 Hazard Declaration
H319
5.1 RIDADR
25kgs
5.1 Caution Statement
P264, P280, P305+P351+P338, P33, P313
5.1 WGK Germany
1
5.1 RTECS
PB2785000
5.1 Safety

Safety Information of Methyl sulfone (CAS NO.67-71-0):
Safety Statements:22-24/25
22:Do not breathe dust?
24/25:Avoid contact with skin and eyes??
WGK Germany:1
RTECS:PB2785000
HS Code:29309070

5.2 Specification

?Methyl sulfone , its CAS NO. is 67-71-0, the synonyms are Dimethyl sulfone ; Dimethyl sulphone ; MSM ; Methyl sulfone ; Methylsulfonylmethane ; Sulfonylbismethane ; Dimethyl sulphone ; Methane, 1,1'-sulfonylbis- ; Methane, sulfonylbis- ; Methyl sulfone ; Methane, sulfonylbis- ; Methylsulfonyl methane ; Sulfonylbismethane .

5.3 Toxicity
LD50 orally in Rabbit: 17000 mg/kg LD50 dermal Rabbit > 5000 mg/kg
5. MSDS

2.Hazard identification

2.1 Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word

Warning

Hazard statement(s)

H315 Causes skin irritation

H319 Causes serious eye irritation

Precautionary statement(s)
Prevention

P264 Wash ... thoroughly after handling.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

Response

P302+P352 IF ON SKIN: Wash with plenty of water/...

P321 Specific treatment (see ... on this label).

P332+P313 If skin irritation occurs: Get medical advice/attention.

P362+P364 Take off contaminated clothing and wash it before reuse.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P337+P313 If eye irritation persists: Get medical advice/attention.

Storage

none

Disposal

none

2.3 Other hazards which do not result in classification

none

9. Other Information
9.0 Mesh
Substances that reduce or suppress INFLAMMATION. (See all compounds classified as Anti-Inflammatory Agents.)
9.1 Mesh Entry Terms
dimethyl sulfone
9.2 Manufacturing Info
Agriculture, forestry, fishing and hunting|Methane, 1,1'-sulfonylbis-: ACTIVE
9.3 Use Classification
Cosmetics -> Solvent
9.4 Usage
Dimethyl sulfone is used as a high-temperature solvent for both inorganic and organic substances. It acts as an intermediate as well as medium in organic synthesis. It plays an important role as a carbon source by the airborne bacteria Afipia. It is also employed as an extraction solvent for the separation of aromatic compounds like benzene, toluene and xylenes from aliphatic hydrocarbons. Further, it is used in the polymerization process. It finds application in pharmaceuticals, agrochemicals, paint and coating materials.
9.5 Merck
14,3258
9.6 BRN
1737717
9.7 description
Dimethyl Sulfone (MSM) is an organic sulfur-containing compound that occurs naturally in a variety of fruits, vegetables, grains, and animals including humans. a white, odorless, slightly bitter-tasting crystalline substance containing 34-percent elemental sulfur, MSM is a normal oxidative metabolite product of dimethyl sulfoxide (DMSO). Cow’s milk is the most abundant source of MSM, containing approximately 3.3 parts per million (ppm). Other foods containing MSM are coffee (1.6 ppm), tomatoes (trace to 0.86 ppm), tea (0.3 ppm), Swiss chard (0.05-0.18 ppm), beer (0.18 ppm), corn (up to 0.11 ppm), and alfalfa (0.07 ppm).MSM has been isolated from plants such as Equisetum arvense, also known as horsetail.
Dimethyl Sulfone has the ability to enhance the body to produce insulin, while it can promote carbohydrate metabolism. It is essential for the synthesis of human collagen. It can not only promote wound healing, but also contribute for metabolic and neurological health requirement of vitamin B and vitamin C, biotin synthesis and activation, so it is known as "naturally beautiful carbon material". Dimethyl Sulfone exists in human skin, hair, nails, bones, muscles and various organs. Once people who are lack of it will get health disorders or diseases. It is the main substance for people to maintain the balance of biological sulfur. It has therapeutic value and healthcare function for people. It is an essential drug for human survial and health protection.
Dimethyl Sulfone
9.8 application
  • Dimethyl sulfone can eliminate the virus, enhance blood circulation, soften tissue, relieve pain, strengthen sinews and bones, calm the spirit, enhance physical strength, maintain skin, make beauty salons, treat the arthritis, oral ulcers, asthma and constipation, dredge the blood vessels, Clear gastrointestinal toxins.
  • Dimethyl sulfone can be used as food and feed additives to supplement the organic sulfur nutrients for humans, pets and livestock.
  • For external use, it can make the skin smooth, supple muscles, and reduce pigmentation. Recently, it surges in the amount as the cosmetic additives.
  • In medicine, it has a good analgesic, it can promote wound healing and others.
  • Dimethyl sulfone is a good penetrant in medicines production.
9.9 Purification methods
Using different purification methods, the products contained different impurities. in the finished product is different purification methods are also different. In general, it is decolored by active carbon, demineralized by ion exchange, and then recrystallized the solvent, dried by vacuum. After that, it is sieved and added an antistatic agent and a slip agent, in order to meet the export requirements. There is no national or ministerial standards. Currently, the countries in the world continue to enforce corporate standards or contract specifications.
9.10 Chemical properties
white needle-like crystals. Melting point 109 ℃, boiling point 238 ℃, relative density 1.1702 (110/0 ℃), refractive index 1.4226, flash point 143 ℃. Soluble in water, ethanol, benzene, methanol and acetone, slightly soluble in ether and chloroform. Stink.
9.11 Uses
Use as high temperature solvent inorganic and organic substances, organic chemical raw materials, food additives and health products raw materials, also used as gas chromatography stationary phase (maximum use temperature 30 ℃, acetone as solvent) and analytical reagents.
9.12 chemical synthesis
Dimethyl sulfone is obtained by oxidizing methyl sulfone using nitric acid as oxidation. Methyl sulfone was oxidized at 140-145 ℃ by nitric oxide. After completion of the reaction, It was cooled and filtered to give white needles crude. Then vacuum distillation, collecting 138-145 ℃ (98.42kPa) distillate products which are the finished goods.
9.13 Chemical Properties
colourless crystals
9.14 Uses
antiinflammatory, antiproliferative, antiparasitic
9.15 Uses
Dimethyl sulfone is a high tempereture solvent for many inorganic and organic substances,it is used as antiinflammatory, antiproliferative, antiparasitic.
9.16 Synthesis Reference(s)
Journal of the American Chemical Society, 91, p. 3992, 1969 DOI: 10.1021/ja01042a075
9.17 Purification Methods
Crystallise the sulfone from water. Dry it over P2O5. [Beilstein 1 IV 1279.]
10. Computational chemical data
  • Molecular Weight: 94.13284g/mol
  • Molecular Formula: C2H6O2S
  • Compound Is Canonicalized: True
  • XLogP3-AA: -0.4
  • Exact Mass: 94.00885060
  • Monoisotopic Mass: 94.00885060
  • Complexity: 85.3
  • Rotatable Bond Count: 0
  • Hydrogen Bond Donor Count: 0
  • Hydrogen Bond Acceptor Count: 2
  • Topological Polar Surface Area: 42.5
  • Heavy Atom Count: 5
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count: 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Isotope Atom Count: 0
  • Covalently-Bonded Unit Count: 1
  • CACTVS Substructure Key Fingerprint: AAADcYBAMABAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAEAQAAAAAAAAAAACCAAAAAAoAAAAAAHAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA==
11. Recommended Suppliers
Global350SuppliersView all >>
  • Products:Pharma &Food Intermediates Water Treatment Chemicals Industrial Specialties Fine Chemicals
  • Tel:86-27-85835203
  • Email:steven@cspharmchem.com
99.9% Dimethyl sulfone; MSM
  • Purity:99%Packing: 200kg/bag FOB
  • Price: 25 USD/kg
  • Time: 2022/11/25
Inquire
  • Products:biotechnology pharmaceutical intermediates biotechnology medical intermediates
  • Tel:0086-0310-15343106358
  • Email:guide@cnyouze.com
Manufacturer of Dimethyl sulfone at Factory Price CAS NO.67-71-0
  • Purity:99%Packing: 200kg/bag FOB
  • Price: 8 USD/kg
  • Time: 2022/11/25
Inquire
  • Products:PMK ethyl glycidate,28578-16-7 ,bmk,5449-12-7,71368-80-4,bromazolam
  • Tel:0371-2223354-+86
  • Email:henan2@yuanlongbio.com
High Purity 99% Methyl Sulfone cas67-71-0
  • Purity:99%Packing: 200kg/bag FOB
  • Price: 10 USD/kg
  • Time: 2022/11/25
Inquire
  • Products:pharmaceutical intermediates Organic raw materialsAnimal and plant extracts1.4BDO, Eutylone,4MMC, JWH ,SGT Peptide, Steroids, Benzos,Dissociatives
  • Tel:86-311-18849057872
  • Email:ceo66@hbainuodi.com
High quality Dimethyl sulfone
  • Purity:99%Packing: 200kg/bag FOB
  • Price: 50 USD/g
  • Time: 2022/11/25
Inquire
  • Products:chemical industry and Pharmaceutical Intermediates products
  • Tel:0086-0311-88888888
  • Email:lisa@zhanyaobio.com
Dimethyl sulfone
  • Purity:99%Packing: 200kg/bag FOB
  • Price: 1 USD/kilogram
  • Time: 2022/11/18
Inquire
12. Realated Product Infomation