Fmoc-N-trityl-L-asparagine
- Iupac Name：(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-4-(tritylamino)butanoic acid
- CAS No.: 132388-59-1
- Molecular Weight：596.683
- Modify Date.: 2022-11-25 02:22
1. Names and Identifiers
- 1.1 Name
- Fmoc-N-trityl-L-asparagine
- 1.2 Synonyms
(2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)-4-oxo-4-(tritylamino)butanoic acid (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-4-oxo-4-(tritylamino)butanoic acid FMOC-ASN(TRT) FMOC-ASN(TRT)-OH FMOC-ASN(XAN)-OH FMOC-ASPARAGINE(TRT) FMOC-L-ASN(TRITYL) FMOC-L-ASN(TRT)-OH FMOC-L-ASPARGINE(TRITYL) Fmoc-N'-trityl-L-asparagine L-Asparagine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-N-(triphenylmethyl)- MFCD00077049 N-(9-Fluorenyl methoxy carbonyl)-N-trityl-L-asparagine N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparagine N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N-trityl-L-asparagine Na-(9-Fluorenylmethoxycarbonyl)-Ng-trityl-L-asparagine N-ALPHA-FMOC-N-GAMMA-TRITYL-L-ASPARAGINE Nα-[(9H-Fluoren-9-ylmethoxy)carbonyl]-NΓ-trityl-L-asparagine Nα-Fmoc-NΓ-trityl-L-asparagine
- View all
- 1.3 CAS No.
- 132388-59-1
- 1.4 CID
- 640248
- 1.5 EINECS(EC#)
- 603-578-8
- 1.6 Molecular Formula
- C38H32N2O5 (isomer)
- 1.7 Inchi
- InChI=1S/C38H32N2O5/c41-35(40-38(26-14-4-1-5-15-26,27-16-6-2-7-17-27)28-18-8-3-9-19-28)24-34(36(42)43)39-37(44)45-25-33-31-22-12-10-20-29(31)30-21-11-13-23-32(30)33/h1-23,33-34H,24-25H2,(H,39,44)(H,40,41)(H,42,43)/t34-/m0/s1
- 1.8 InChIkey
- KJYAFJQCGPUXJY-UMSFTDKQSA-N
- 1.9 Canonical Smiles
- C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NC(=O)CC(C(=O)O)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46
- 1.10 Isomers Smiles
- C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NC(=O)C[C@@H](C(=O)O)NC(=O)OCC4C5=CC=CC=C5C6=CC=CC=C46
2. Properties
- 2.1 Density
- 1.271
- 2.1 Melting point
- 205℃
- 2.1 Boiling point
- 858.1 oC at 760 mmHg
- 2.1 Refractive index
- -19 ° (C=1, DMF)
- 2.1 Flash Point
- 472.8oC
- 2.1 Precise Quality
- 596.23100
- 2.1 PSA
- 104.73000
- 2.1 logP
- 7.25850
- 2.1 Solubility
- <0.00005g/l
- 2.2 Appearance
- White to off white free flowing powder
- 2.3 Storage
- Keep Cold.
- 2.4 Chemical Properties
- white crystal powde Fmoc-N-trityl-L-asparagineSupplier
- 2.5 pKa
- 3.79±0.10(Predicted)
- 2.6 Water Solubility
- 1mmol in 2ml DMF Clearly Soluble
- 2.7 StorageTemp
- 2-8°C
3. Safety and Handling
- 3.1 Risk Statements
- 53
- 3.1 Safety Statements
- S24/25
- 3.1 Hazard Class
- IRRITANT
- 3.1 Hazard Declaration
- H413
- 3.1 RIDADR
- UN 3077 9 / PGIII
- 3.1 Caution Statement
- P273, P501
- 3.1 WGK Germany
- 2
- 3.1 Safety
-
Safety Statements: 24/25?
S24/25: Avoid contact with skin and eyes
WGK Germany: 2
F: 3-10?
F3: Hygroscopic
F 10: Keep under argon
HazardClass: IRRITANT
- 3.2 Specification
-
?Fmoc-Asn(Trt)-OH (132388-59-1) (CAS NO.132388-59-1) is also called as N-fmoc-l-asn(trt)-oh ; N-(9-fluorenyl methoxy carbonyl)-n-trityl-l-asparagine ; N-alpha-[(9h-fluoren-9-ylmethoxy)carbonyl]-n-gamma-trityl-l-asparagine ; N-alpha-(9-fluorenylmethyloxycarbonyl)-n-beta-trityl-l-asparagine ; N-alpha-9-fluorenylmethoxycarbonyl-n-omega-trityl-l-asparagine ; Nalpha-(9-fluorenylmethoxycarbonyl)-nr-trityl-l-asparagine ; N-alpha-(9-fluorenylmethoxycarbonyl)-n-beta-trityl-l-asparagine ; Nalpha-(9-Fluorenylmethoxycarbonyl)-Ngamma-trityl-L-asparagine ; Fmoc-N-trityl-L-asparagine .
- 3.3 Toxicity
- LD50 orally in Rabbit: > 2000 mg/kg
4. MSDS
2.Hazard identification
2.1 Classification of the substance or mixture
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 4
2.2 GHS label elements, including precautionary statements
| Pictogram(s) | No symbol. |
| Signal word | No signal word. |
| Hazard statement(s) | H413 May cause long lasting harmful effects to aquatic life |
| Precautionary statement(s) | |
| Prevention | P273 Avoid release to the environment. |
| Response | none |
| Storage | none |
| Disposal | P501 Dispose of contents/container to ... |
2.3 Other hazards which do not result in classification
none
5. Synthesis Route
132388-59-1Total: 4 Synthesis Route
7. Other Information
- 7.0 BRN
- 4343823
- 7.1 Chemical Properties
- white crystal powde
- 7.2 Uses
- Fmoc-Asn(Trt)-OH, is an amino acid derivative used in chemical synthesis and peptide chemistry.
8. Computational chemical data
- Molecular Weight: 596.683g/mol
- Molecular Formula: C38H32N2O5
- Compound Is Canonicalized: True
- XLogP3-AA: 6.6
- Exact Mass: 596.23112213
- Monoisotopic Mass: 596.23112213
- Complexity: 931
- Rotatable Bond Count: 11
- Hydrogen Bond Donor Count: 3
- Hydrogen Bond Acceptor Count: 5
- Topological Polar Surface Area: 105
- Heavy Atom Count: 45
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count: 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Isotope Atom Count: 0
- Covalently-Bonded Unit Count: 1
- CACTVS Substructure Key Fingerprint: AAADcfB/OAAAAAAAAAAAAAAAAAAAAYAAAAAwYMGDAAAAAGABVAAAHgAQCAAADajhmAYwCILABgCIAiHSGACCAAAgAAAIiIGIBIkKIDqA0TGMYAhk1gGYiAe3wPAOgAAAAAAQAAAAAAAAACAAAQAACAAAAA==
9. Question & Answer
-
Fmoc-N-trityl-L-asparagine, also known as N-trityl-L-asparagine, is a derivative of asparagine. It has the chemical formula C38H31N2O5 and a molecular weight of 595.6637. It is a white to grayish-whit..
10. Recommended Suppliers
-
- Products:Pharmaceutical Intermediate , Apis , Food Additives , Herbal Extracts , Fine Chemicals , ...
- Tel:00-86-13023277276
- Email:hanna@xljxcl.com
-
- Products:Pharmaceutical intermediates
- Tel:173-31933971-17331933971
- Email:deasea125996@gmail.com
-
- Products:Chemical products
- Tel:86-571-88938639
- Email:sales-gc@dycnchem.com
-
- Products:We mainly export sles, labsa, glycerin, propylene glycol, castic soda, all kinds of plastic particles, fertilizer and other chemical products
- Tel:00-86-15030815998
- Email:lucky@anrunchem.com
-
- Products:We ZERchem, facing global High-tech pharmaceutical raw materials, high value-added new type intermediates fine chemicals custom synthesis, scale-up production and rare chemicals trade.
- Tel:+86-571-82512721
- Email:sales@zeerrui.com
11. Realated Product Infomation
skype
1YR
