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Gelatin
- CAS No.: 9000-70-8
- Molecular Weight：0
- Modify Date.: 2022-12-11 08:35
- Introduction: 1. It can be applied to printing and dyeing and other industries2. As a thickening agent, China provided that it can be used for all types of food with appropriate application according to production needs. It can also be used as the clarification agent of alcohol and hydrophobic colloidal stabilizer.3. It is a kind of hydrophilic colloid with protective colloid effect. It can be used as a hydrophobic colloid stabilizer, emulsifier. It is also a kind of amphoteric electrolyte and can be condensed into pieces of charged particles, which can be used as the clarifier of wine and alcohol. As a dispersant, binder, thickener, stabilizer and emulsifier, it is widely used in photosensitive materials, pharmaceuticals, food, paper, printing, textile, printing and dyeing, electroplating, cosmetics, bacterial culture and pesticide. 4. It can be used as the protective colloid during turbidity or colorimetric determination; also used for the preparation of photographic plate and medium.5. It can be used as the food quality improver6. Thickeners; stabilizers; clarifying agents; blowing agents.7. Gelatin is a hydrophilic colloid with the nature of protecting colloid. It can be used as a hydrophobic colloid stabilizer, emulsifier. But also as the amphoteric electrolyte, it can be enable the condensation of the charged particles into pieces in the aqueous solution; it can be used as wine, alcohol clarifier.8. It can be used as excipient suspensions, and media.9. According to the functional properties of gelatin, its application can be divided into two categories. Class I: taking its colloidal protective capacity as a dispersant for the production of PVC, photographic materials, bacterial culture and pharmaceutical, food (such as candy, ice cream, cod liver oil capsules, etc.). Class II: application of its adhesive capacity as adhesive for being applied to paper, printing, textile, printing and electroplating and other industrial sectors. According to different applications, the quality requirements of gelatin is not the same. Gelatin, when being used as adhesive agent in adhesive tape, paper containers, paper tubes and binding, etc. has the bonding strength be the main value factor; when applied to the fields of photography, food and medicine, people emphasize more on the product purity. The national standard number of edible gelatin in China is GB6783-86; the usage range and maximum allowable amount should be referred to GB2760-86.
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1. Names and Identifiers
- 1.1 Name
- Gelatin
- 1.2 Synonyms
11H-Dibenzo(b,e)(1,4)dioxepin-11-one,1,6-bis(1-methyl-1-propenyl)-3,8-dihydroxy-4,9-dimethyl-,(Z,Z) 11H-Dibenzo(b,e)(1,4)dioxepin-11-one,3,8-dihydroxy-4,9-dimethyl-1,6-bis(1-methyl-1-propenyl)-,(Z,Z) absorbablegelatinsponge BOVINEGELATIN EINECS 232-554-6 Folipastatin food-grade gelatin Galfoam gelatinfoam gelfoam Hydrolyzed Fish Collagen/Marine Collagen MFCD00081638 PORCINEGELATIN PRIONEX(R) GELATIN TELEOSTEAN GELATIN
- 1.3 CAS No.
- 9000-70-8
- 1.4 CID
- 14791
- 1.5 EINECS(EC#)
- 232-554-6
- 1.6 Molecular Formula
- C6H12O6 (isomer)
- 1.7 Inchi
- InChI=1S/Mg.2H2O/h;2*1H2/q+2;;/p-2
- 1.8 InChkey
- VTHJTEIRLNZDEV-UHFFFAOYSA-L
- 1.9 Canonical Smiles
- [OH-].[OH-].[Mg+2]
- 1.10 Isomers Smiles
- [OH-].[OH-].[Mg+2]
2. Properties
- 2.1 Density
- 1.2
- 2.1 Melting point
- >226°C (dec.)
- 2.1 Boiling point
-
Vapour density:
- 2.1 Precise Quality
- 260.87200
- 2.1 PSA
- 0.00000
- 2.1 logP
- 0.00000
- 2.1 Solubility
- H2O: 67?mg/mL at?50?°C, slightly hazy, slightly yellow
- 2.2 Appearance
- powder
- 2.3 Storage
- Ambient temperatures.
- 2.4 Chemical Properties
- Industrial gelatin appears as colorless or light yellow transparent or translucent flakes or powder. It is tasteless and odorless. It will absorb water for swelling in cold water. It can be dissolved in hot water, being soluble in glycerol and acetic acid, but insoluble in ethanol and ether.
- 2.5 Color/Form
- Amorphous powder
White, hexagonal crystals
Granules
- 2.6 Odor
- Musty odour
- 2.7 PH
- 4.0-6.0 (25℃, 67mg/mL in H2O)
- 2.8 pKa
- pKa 3.7to4.5(H2O t=25 I=0.00 N2atmosphere) (Uncertain)
- 2.9 Water Solubility
- H2O: 67?mg/mL at?50?°C, slightly hazy, slightly yellow | SOLUBLE IN HOT WATER
- 2.10 Spectral Properties
- Index of refraction: 1.559, 1.580
- 2.11 Stability
- Stable. Hygroscopic. Incompatible with strong oxidizing agents.
- 2.12 StorageTemp
- 2-8°C
3. Use and Manufacturing
- 3.1 Agricultural Uses
- Gelatin is a colorless or pale yellow water-soluble protein obtained by boiling collagen with water and evaporating the water. It is an ingredient in jellies and baked goods. It is also used to make medicinal capsules, and coat photographic films.
- 3.2 Definition
- Amixture of proteins obtained by hydrolysisof collagen by boiling skin, ligaments, tendons,etc. Its production differs from that of animalglue in that the raw materials are selected,cleaned, and treated with special care so that theproduct is cleaner
- 3.3 General Description
- Gelatin, NF, is a protein obtained by the partial hydrolysis of collagen, an albuminoid found in bones, skin, tendons, cartilage, hoofs, and other animal tissues. Gelatin is used in the preparation of capsules, in the coating of tablets, and, with glycerin, as a vehicle for suppositories. It has also been used as a vehicle when slow absorption is desired for drugs.
- 3.4 Usage
- 1. It can be applied to printing and dyeing and other industries2. As a thickening agent, China provided that it can be used for all types of food with appropriate application according to production needs. It can also be used as the clarification agent of alcohol and hydrophobic colloidal stabilizer.3. It is a kind of hydrophilic colloid with protective colloid effect. It can be used as a hydrophobic colloid stabilizer, emulsifier. It is also a kind of amphoteric electrolyte and can be condensed into pieces of charged particles, which can be used as the clarifier of wine and alcohol. As a dispersant, binder, thickener, stabilizer and emulsifier, it is widely used in photosensitive materials, pharmaceuticals, food, paper, printing, textile, printing and dyeing, electroplating, cosmetics, bacterial culture and pesticide. 4. It can be used as the protective colloid during turbidity or colorimetric determination; also used for the preparation of photographic plate and medium.5. It can be used as the food quality improver6. Thickeners; stabilizers; clarifying agents; blowing agents.7. Gelatin is a hydrophilic colloid with the nature of protecting colloid. It can be used as a hydrophobic colloid stabilizer, emulsifier. But also as the amphoteric electrolyte, it can be enable the condensation of the charged particles into pieces in the aqueous solution; it can be used as wine, alcohol clarifier.8. It can be used as excipient suspensions, and media.9. According to the functional properties of gelatin, its application can be divided into two categories. Class I: taking its colloidal protective capacity as a dispersant for the production of PVC, photographic materials, bacterial culture and pharmaceutical, food (such as candy, ice cream, cod liver oil capsules, etc.). Class II: application of its adhesive capacity as adhesive for being applied to paper, printing, textile, printing and electroplating and other industrial sectors. According to different applications, the quality requirements of gelatin is not the same. Gelatin, when being used as adhesive agent in adhesive tape, paper containers, paper tubes and binding, etc. has the bonding strength be the main value factor; when applied to the fields of photography, food and medicine, people emphasize more on the product purity. The national standard number of edible gelatin in China is GB6783-86; the usage range and maximum allowable amount should be referred to GB2760-86.
4. Safety and Handling
- 4.1 Hazard Codes
- Xi
- 4.1 Risk Statements
- 36/37/38
- 4.1 Safety Statements
- 24/25-36/37/39-27-26
- 4.1 Exposure Standards and Regulations
- Antacid products for over-the-counter (OTC) human use. Magnesium hydroxide is included on this list of specific active ingredients.
- 4.2 DisposalMethods
- SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
- 4.3 RIDADR
- NONH for all modes of transport
- 4.3 Safety Profile
- An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits acrid smoke and irritating fumes.
- 4.4 Formulations/Preparations
- MILK OF MAGNESIA USP, IS AN AQUEOUS SUSPENSION OF MAGNESIUM HYDROXIDE CONTAINING 7.0-8.5% OF MG(OH)2. EACH MILLILITER IS CAPABLE OF NEUTRALIZING APPROX 2.7 MEQ OF ACID. ...MAGNESIUM HYDROXIDE IS ALSO AVAIL AS MAGNESIA TABLETS...GENERALLY CONTAIN 325 MG EACH, WHICH CAN NEUTRALIZE 11.2 MEQ OF ACID.
USP; 250 ML & 500 ML BOTTLES WITH ALUMINUM HYDROXIDE GEL; 250 ML, 375 ML, 500 ML & 1 L BOTTLES.
SUSPENSION OF 30% MAGNESIUM HYDROXIDE IN WATER: HYDRO-MAGMA.
MAGNESIUM HYDROXIDE DRUG AVAILABLE GENERICALLY: POWDER; TABLETS 300 & 600 MG.
VET: PRIMARILY IN LAXATIVE MIXTURES FOR SUSPENSION IN LARGE QUANTITIES OF WATER, OCCASIONALLY IN BOLUS, & OCCASIONALLY AS MILK OF MAGNESIA; MAGMA MAGNESII, CREAM OF MAGNESIA, MIXTURE OF MAGNESIUM HYDROXIDE, & MISTURA MAGNESII HYDROXIDI (APPROX AN 8% AQUEOUS SOLUTION).
MAGNESIUM HYDROXIDE IS USUALLY MARKETED IN COMBINATION WITH OTHER ANTACIDS.
GRADES: TECHNICAL, NF, FCC.
VET: MAGNALOX BOLUSES, EACH BOLUS CONTAINS: MAGNESIUM HYDROXIDE 27 G; GINGER 200 MG, & CAPSICUM 50 MG.
A mixture of salts, available as Maalox, Mylanta, Gelusil, and Aludrox, contains magnesium hydroxide, Mg(OH)2, and variable amounts of aluminum oxide in the form of aluminum hydroxide and hydrated aluminum oxide, ie, 2.9-4.2% magnesium hydroxide and 2.0-2.4% aluminum oxide, Al2O3, for a mixture of 4.9-6.6% combined magnesium hydroxide and aluminum oxide. This mixture may contain a flavoring and antimicrobial agents in a total amount not to exceed 0.5% ... .
- 4.5 Incompatibilities
- Gelatin is an amphoteric material and will react with both acids andbases. It is also a protein and thus exhibits chemical propertiescharacteristic of such materials; for example, gelatin may behydrolyzed by most proteolytic systems to yield its amino acidcomponents.Gelatin will also react with aldehydes and aldehydic sugars,anionic and cationic polymers, electrolytes, metal ions, plasticizers,preservatives, strong oxidizers, and surfactants. It is precipitated byalcohols, chloroform, ether, mercury salts, and tannic acid. Gels canbe liquefied by bacteria unless preserved.Some of these interactions are exploited to favorably alter thephysical properties of gelatin: for example, gelatin is mixed with aplasticizer, such as glycerin, to produce soft gelatin capsules andsuppositories; gelatin is treated with formaldehyde to producegastroresistance.
- 4.6 WGK Germany
- 3
- 4.6 RTECS
- LX8580000
- 4.6 Reactivities and Incompatibilities
- Phosphorus boiled with alkaline hydroxides yields mixed phosphines which may ignite spontaneously in air. /Alkaline hydroxides/
ALKALI & OTHER ALKALINE EARTH COMPD...MAGNESIUM COMPD...CAUSE EXPLOSIVE DECOMP OF MALEIC ANHYDRIDE.
- 4.7 Safety
-
Safety Description of?Gelatin (CAS NO.9000-70-8): 24/25?
S24/25: Avoid contact with skin and eyes.
- 4.8 Specification
-
white to slightly yellow powder
Safety Statements:24/25-36/37/39-27-26
24/25:Avoid contact with skin and eyes
36/37/39:Wear suitable protective clothing, gloves and eye/face
protection
27:Take off immediately all contaminated clothing
26:In case of contact with eyes, rinse immediately with plenty
of water and seek medical advice
- 4.9 Toxicity
- LD50 orally in Rabbit: > 5000 mg/kg
5. MSDS
2.Hazard identification
2.1 Classification of the substance or mixture
Not classified.
2.2 GHS label elements, including precautionary statements
| Pictogram(s) | No symbol. |
| Signal word | No signal word. |
| Hazard statement(s) | none |
| Precautionary statement(s) | |
| Prevention | none |
| Response | none |
| Storage | none |
| Disposal | none |
2.3 Other hazards which do not result in classification
none
7. Other Information
- 7.0 Merck
- 13,4393
- 7.1 Usage limit
- GB 2760-96: can be used for all types of food; take GMP as the limitation.
FAO/WHO(1984, g/kg): Cream cheese 5; cooked ham, cooked pig forelegs, according to GMT; cottage cheese 5 (by cream); cream 5 (only used for Pasteurized whipped cream or whipped cream with ultra-high temperature sterilization cream and sterile cream).
During the manufacturing of ice cream, gelatin can be used as a protective colloid to prevent the ice crystal from increasing, making the product taste fine, need to be added of about 0.5%. Yogurt, cheese and other dairy products needs to be added of about 0.25%, being able to prevent precipitation of water and enabling the fine texture.
In the manufacture of gelatin dessert (dessert, the main ingredient is gelatin), candy, candy, protein sugar, chocolate, etc. (add 1% to 3.5%, up to 12%).
It is widely applied of gelatin in the luncheon meat, corned beef and other canned food so that the gravy water can be combined to maintain the product shape, humidity and flavor; add about 1% to 5% the weight of meat.
It can also be used as a thickening of soy sauce.
- 7.2 Standard for Maximum Allowable Amount
-
- 7.3 Usage
- Gelatin is used for preparing slides for histochemistry and light microscope autoradiography. Gelatin has also been added to cell culture plates and improves the attachment of a variety of cell types. Additionally, gelatin can inhibit crystallization in bacteriology studies. In addition it is an excellent diluents for primary and secondary antibodies.
- 7.4 Usage
- Gelatin is used to make lithographic and printing inks, plastic compounds, artificial silk, matches and pharmaceutical capsules. It finds application in light filters for mercury lamps, clarifying agent, pharmaceutical aid (suspending agent) and gelling component. It acts as an additive for foods and microencapsulating agent. Further, it is employed in electroplating, hectographic masters, paper and textile sizing, cosmetics, ointments and other medical and veterinary applications. It is useful in histochemistry, bacterial culture media and light microscope autoradiography. In addition to this, it is used to make the shells of paintballs and to hold silver halide crystals in an emulsion, in virtually all photographic films and photographic papers.
8. Computational chemical data
- Molecular Weight: 0g/mol
- Molecular Formula: C6H12O6
- Compound Is Canonicalized: True
- XLogP3-AA: null
- Exact Mass: 57.9905210
- Monoisotopic Mass: 57.9905210
- Complexity: 2.8
- Rotatable Bond Count: 0
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 2
- Topological Polar Surface Area: 2
- Heavy Atom Count: 3
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count: 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Isotope Atom Count: 0
- Covalently-Bonded Unit Count: 3
- CACTVS Substructure Key Fingerprint: AAADcQAAMAAAACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA==
9. Question & Answer
-
Gelatin is a translucent, colorless, flavorless food ingredient, derived from collagen taken from animal body parts. Brittle when dry and gummy when moist. Gelatin is made from collagen. Collagen is one of the materials that make up cartilage and bone. Some people think gelatin might help for arthr...
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- Time: 2023/04/23
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