3D Mol Similar

Glycinamide hydrochloride

Iupac Name：2-aminoacetamide;hydrochloride

CAS No.: 1668-10-6

Molecular Weight：110.54

Modify Date.: 2022-12-06 15:54

Request For Quotation

1. Names and Identifiers

1.1 Name: Glycinamide hydrochloride
1.2 Synonyms: Acetamide, 2-amino-, monohydrochloride Acetamide, 2-amino-,hydrochloride (1:1) Aminoacetamide hydrochloride GLYCINAMIDE HCI Glycinamide hydrochl GLYCINAMIDEHYDROCHLORIDE,BIOLOGICALBUFFER

1.3 CAS No.: 1668-10-6

1.4 EINECS(EC#): 216-789-1

1.5 Molecular Formula: C2H7ClN2O (isomer)

1.6 Inchi: InChI=1S/C2H6N2O.ClH/c3-1-2(4)5;/h1,3H2,(H2,4,5);1H

1.7 InChIkey: WKNMKGVLOWGGOU-UHFFFAOYSA-N

1.8 Canonical Smiles: Cl.NCC(N)=O

1.9 Isomers Smiles: C(C(=O)N)N.Cl

2. Properties

2.1 Melting point: 204?°C (dec.)(lit.)

2.1 pKa: 8.20(at 20℃)

2.2 StorageTemp: Inert atmosphere,Room Temperature

3. Safety and Handling

3.1 Hazard Codes: Xi

3.1 Risk Statements: 36/37/38

3.1 Safety Statements: 22-24/25-37/39-26

3.1 WGK Germany: 3

4. MSDS

2.Hazard identification

2.1 Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity \u2013 single exposure, Category 3

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word	Warning
Hazard statement(s)	H315 Causes skin irritation H319 Causes serious eye irritation H335 May cause respiratory irritation
Precautionary statement(s)
Prevention	P264 Wash ... thoroughly after handling. P280 Wear protective gloves/protective clothing/eye protection/face protection. P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area.
Response	P302+P352 IF ON SKIN: Wash with plenty of water/... P321 Specific treatment (see ... on this label). P332+P313 If skin irritation occurs: Get medical advice/attention. P362+P364 Take off contaminated clothing and wash it before reuse. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313 If eye irritation persists: Get medical advice/attention. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P312 Call a POISON CENTER/doctor/\u2026if you feel unwell.
Storage	P403+P233 Store in a well-ventilated place. Keep container tightly closed. P405 Store locked up.
Disposal	P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

View all

5. Synthesis Route

1668-10-6Total: 3 Synthesis Route

540-61-4 33 Suppliers

1668-10-6 220 Suppliers

Literatures:
Tetrahedron Letters, , vol. 31, # 8 p. 1169 - 1170
Yield: ~88%

5680-79-5 234 Suppliers

1668-10-6 220 Suppliers

Literatures:
Journal fur Praktische Chemie - Chemiker - Zeitung, , vol. 338, # 3 p. 251 - 256
Yield: null

141509-41-3

1668-10-6 220 Suppliers

114533-59-4

Literatures:
Journal of Organic Chemistry, , vol. 57, # 13 p. 3662 - 3672
Yield: ~33%

6. Other Information

6.0 BRN: 3554199

6.1 Chemical Properties: Crystalline

6.2 Uses: Glycinamide hydrochloride is a buffer that is useful in the physiological pH range. And it is also used as a pharmaceutical intermediate, in the organic synthesis.

6.3 Uses

Glycinamide hydrochloride may be used in the synthesis of [M(glycinamidato-N,N′)(ptpy)₂] where ptpy = 2-(p-tolyl)pyridinato) and M= Rh or Ir.
It may be used in the synthesis of the following glycinamide-based imidazolidinones: