Growth hormone releasing peptide
- Iupac Name：6-amino-2-[[2-[[2-[2-[[2-[[2-amino-3-(1H-imidazol-5-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoylamino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenylpropanoyl]amino]hexanamide
- CAS No.: 87616-84-0
- Molecular Weight：873.032
- Modify Date.: 2022-10-31 06:17
1. Names and Identifiers
- 1.1 Name
- Growth hormone releasing peptide
- 1.2 Synonyms
(2S)-6-amino-2-[[2-[[(2S)-2-[[(2S)-2-[[(2R)-2-[[(2S)-2-amino-3-(3H-imidazol-4-yl)propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]propanoyl]amino]-3-(1H-indol-3-yl)propanoyl]amino]-3-phenyl-propanoyl]amino]hexanamide (D-TRP7,ALA8,D-PHE10)-A-MELANOCYTE*STIMU LATING HORM (D-trp7,ala8,D-phe10)-A-melanocyte*stimulating ho [d-trp7, ala8, d-phe10]-α-melanocyte stimulating hormone amide fragment 6-11 D-TRP7,ALA8,D-PHE10]-A-MELANOCYTESTIMULATINGHORMONEAMIDEFRAGMENT6-11 GH-Releasing hexapeptide 6 GH-Releasing peptide GHRP-6 Acetate Growth growth hormone releasing hexapeptide High Purity Ghrp-6 Peptide For Lean Muscle Mass CAS NO.87616-84-0 CAS NO.87616-84-0 His(1)-lys(6)-ghrp L-Histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide L-Lysinamide, L-histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl- MFCD00872694
- 1.3 CAS No.
- 87616-84-0
- 1.4 CID
- 4345065
- 1.5 EINECS(EC#)
- 212-729-3
- 1.6 Molecular Formula
- C46H56N12O6 (isomer)
- 1.7 Inchi
- InChI=1S/C46H56N12O6/c1-27(54-44(62)39(20-29-23-51-35-15-7-5-13-32(29)35)57-43(61)34(48)22-31-25-50-26-53-31)42(60)56-40(21-30-24-52-36-16-8-6-14-33(30)36)46(64)58-38(19-28-11-3-2-4-12-28)45(63)55-37(41(49)59)17-9-10-18-47/h2-8,11-16,23-27,34,37-40,51-52H,9-10,17-22,47-48H2,1H3,(H2,49,59)(H,50,53)(H,54,62)(H,55,63)(H,56,60)(H,57,61)(H,58,64)
- 1.8 InChkey
- WZHKXNSOCOQYQX-UHFFFAOYSA-N
- 1.9 Canonical Smiles
- CC(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCCCN)C(=O)N)NC(=O)C(CC4=CNC5=CC=CC=C54)NC(=O)C(CC6=CN=CN6)N
- 1.10 Isomers Smiles
- CC(C(=O)NC(CC1=CNC2=CC=CC=C21)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CCCCN)C(=O)N)NC(=O)C(CC4=CNC5=CC=CC=C54)NC(=O)C(CC6=CN=CN6)N
2. Properties
- 2.1 Density
- 1.333
- 2.1 Boiling point
- 1407°C at 760 mmHg
- 2.1 Refractive index
- 1.664
- 2.1 Flash Point
- 804.7°C
- 2.1 Precise Quality
- 872.44500
- 2.1 PSA
- 300.89000
- 2.1 logP
- 5.08380
- 2.1 Appearance
- Lyophilized powder
- 2.2 Storage
- ?20°C
- 2.3 pKa
- 13.42±0.46(Predicted)
- 2.4 StorageTemp
- ?20°C
3. Safety and Handling
- 3.1 RIDADR
- NONH for all modes of transport
- 3.1 WGK Germany
- 3
4. MSDS
2.Hazard identification
2.1 Classification of the substance or mixture
no data available
2.2 GHS label elements, including precautionary statements
| Pictogram(s) | no data available |
| Signal word | no data available |
| Hazard statement(s) | no data available |
| Precautionary statement(s) | |
| Prevention | no data available |
| Response | no data available |
| Storage | no data available |
| Disposal | no data available |
2.3 Other hazards which do not result in classification
no data available
5. Other Information
- 5.0 Description
- Growth hormone-releasing peptides (GHRPs) are synthetic, non-natural peptides endowed with potent stimulatory effects on somatotrope secretion in animals and humans. They have no structural homology with GHRH and act via specific receptors present either at the pituitary or the hypothalamic level both in animals and in humans.
- 5.1 Uses
- Growth hormone releasing peptide-6 can promote the secretion of growth hormone, regulate food intake, increase weight, and promote animal growth.
- 5.2 Uses
- L-Histidyl-D-tryptophyl-L-alanyl-L-tryptophyl-D-phenylalanyl-L-lysinamide is a growth hormone releasing peptide.
- 5.3 Mechanism of action
- Growth hormone releasing peptide is generally accepted that GHRPs stimulate the release of GH by acting at the level of the pituitary through a receptor different to that for the endogenous GH-releasing hormone (GHRH). In addition, it has been reported that there are specific binding sites for these peptides in the hypothalamus and that systemic administration of GHRPs increases the expression of the immediate early gene c-fos in a subpopulation of hypothalamic neurons.
- 5.4 用途
-
GHRP-2 is a synthetic hexapeptide Growth Hormone Releasing Peptide (GHRP), which acts on the hypothalamus and the pituitary gland to release growth hormone with a slight stimulator effect on Prolactin, ACTH and Cortisol levels.
6. Computational chemical data
- Molecular Weight: 873.032g/mol
- Molecular Formula: C46H56N12O6
- Compound Is Canonicalized: True
- XLogP3-AA: 1.9
- Exact Mass: 872.44457755
- Monoisotopic Mass: 872.44457755
- Complexity: 1570
- Rotatable Bond Count: 23
- Hydrogen Bond Donor Count: 11
- Hydrogen Bond Acceptor Count: 9
- Topological Polar Surface Area: 301
- Heavy Atom Count: 64
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count: 6
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Isotope Atom Count: 0
- Covalently-Bonded Unit Count: 1
- CACTVS Substructure Key Fingerprint: AAADcfB/+AAAAAAAAAAAAAAAAAAAAWLFgAAwYMAAAAAAAFgB/gAAHgAQAAAADCjBngQ/0PbJkACoAzV3dACCgC2xEqAJ2aG4dJiIaPLA2bGUIAholgLIyCccicCOgAAAAAACAAAAAAAAAAQAAAAAAAAAAA==
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8. Realated Product Infomation
skype
1YR
