L(+)-2-Aminobutyric acid
- Iupac Name：(2S)-2-aminobutanoic acid
- CAS No.: 1492-24-6
- Molecular Weight：103.12
- Modify Date.: 2022-11-29 08:30
- Introduction: aminobutyric acid is an amino acid with water-binding properties and possible anti-inflammatory capacities.
View more+
1. Names and Identifiers
- 1.1 Name
- L(+)-2-Aminobutyric acid
- 1.2 Synonyms
(S)-(+)-2-Amino butiric acid (S)-(+)-α-Aminobutyric acid Aminobutyric acid, 2- EINECS 216-083-3 H-ABU-OH L-2-AMINOBUTANOIC ACID L-2-AMINO-N-BUTYRIC ACID L-ABU L-ALPHA-AMINO-N-BUTYRIC ACID L-Butyrine L-Ethylglycine L-Homoalanine MFCD00064415 NSC 97060 S-Butyrine
- 1.3 CAS No.
- 1492-24-6
- 1.4 CID
- 80283
- 1.5 EINECS(EC#)
- 216-083-3
- 1.6 Molecular Formula
- C4H9NO2 (isomer)
- 1.7 Inchi
- InChI=1S/C4H9NO2/c1-2-3(5)4(6)7/h3H,2,5H2,1H3,(H,6,7)/t3-/m0/s1
- 1.8 InChkey
- QWCKQJZIFLGMSD-VKHMYHEASA-N
- 1.9 Canonical Smiles
- CCC(C(=O)O)N
- 1.10 Isomers Smiles
- CC[C@@H](C(=O)O)N
2. Properties
- 2.1 Density
- 1.2300 (estimate)
- 2.1 Melting point
- 300 °C
- 2.1 Boiling point
- 215.2 °C at 760 mmHg
- 2.1 Refractive index
- 1.4650 (estimate)
- 2.1 Flash Point
- 83.9 °C
- 2.1 Precise Quality
- 103.06300
- 2.1 PSA
- 63.32000
- 2.1 logP
- 0.50860
- 2.1 Solubility
- 22.7 g/100 mL (22 oC) in water
- 2.2 Appearance
- Solid
- 2.3 Storage
- Ambient temperatures.
- 2.4 Chemical Properties
- White Crystalline Solid
- 2.5 Color/Form
- White to beige
- 2.6 Physical
- Solid
- 2.7 pKa
- 2.29(at 25℃)
- 2.8 Water Solubility
- 1.438e+005 mg/L @ 25 °C (est)
- 2.9 Stability
- Stable under normal temperatures and pressures.
- 2.10 StorageTemp
- Store at RT.
3. Use and Manufacturing
- 3.1 Definition
- ChEBI: An optically active form of alpha-aminobutyric acid having L-configuration.
- 3.2 GHS Classification
- Signal: Warning
GHS Hazard Statements
Aggregated GHS information provided by 37 companies from 2 notifications to the ECHA C&L Inventory.
H317 (94.59%): May cause an allergic skin reaction [Warning Sensitization, Skin]
Information may vary between notifications depending on impurities, additives, and other factors. The percentage value in parenthesis indicates the notified classification ratio from companies that provide hazard codes. Only hazard codes with percentage values above 10% are shown.
Precautionary Statement Codes
P261, P272, P280, P302+P352, P321, P333+P313, P363, and P501
- 3.3 Purification Methods
- Crystallise butyrine from aqueous EtOH, and the melting point depends on heating rate but has m 303o in a sealed tube. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 2399 IR: 2401 1961, Beilstein 4 III 1294, 4 IV 2584.] L(+)-2-Aminobutyric acidSupplier
- 3.4 Usage
- aminobutyric acid is an amino acid with water-binding properties and possible anti-inflammatory capacities.
4. Safety and Handling
- 4.1 Hazard Codes
- Xi
- 4.1 Risk Statements
- 43
- 4.1 Safety Statements
- 36/37
- 4.1 Hazard Declaration
- H317
- 4.1 RIDADR
- NONH for all modes of transport
- 4.1 Caution Statement
- P280
- 4.1 WGK Germany
- 3
5. MSDS
2.Hazard identification
2.1 Classification of the substance or mixture
Skin sensitization, Category 1
2.2 GHS label elements, including precautionary statements
| Pictogram(s) |  |
| Signal word | Warning |
| Hazard statement(s) | H317 May cause an allergic skin reaction |
| Precautionary statement(s) | |
| Prevention | P261 Avoid breathing dust/fume/gas/mist/vapours/spray. P272 Contaminated work clothing should not be allowed out of the workplace. P280 Wear protective gloves/protective clothing/eye protection/face protection. |
| Response | P302+P352 IF ON SKIN: Wash with plenty of water/... P333+P313 If skin irritation or rash occurs: Get medical advice/attention. P321 Specific treatment (see ... on this label). P362+P364 Take off contaminated clothing and wash it before reuse. |
| Storage | none |
| Disposal | P501 Dispose of contents/container to ... |
2.3 Other hazards which do not result in classification
none
7. Synthesis Route
1492-24-6Total: 66 Synthesis Route
9. Other Information
- 9.0 Usage
- L-(+)-2-Aminobutyric acid is used in the biosynthesis of nonribosomal peptides. It acts as a receptor antagonist. It is also used as a chiral reagent. Further, it is used in the determination of substrate of glutamyl cysteine acid synthase. In addition to this, it is also utilized as a drug intermediate.
- 9.1 Mesh Entry Terms
- (2S)-2-aminobutanoic acid
- 9.2 Manufacturing Info
- Butanoic acid, 2-amino-, (2S)-: ACTIVE
- 9.3 Use Classification
- Fatty Acyls [FA] -> Fatty Acids and Conjugates [FA01] -> Amino fatty acids [FA0110]|Cosmetics -> Hair conditioning
- 9.4 Merck
- 14,428
- 9.5 BRN
- 1720935
- 9.6 Chemical Properties
- White Crystalline Solid
- 9.7 Uses
- Receptor antagonist
- 9.8 Uses
- aminobutyric acid is an amino acid with water-binding properties and possible anti-inflammatory capacities.
- 9.9 Definition
- ChEBI: An optically active form of alpha-aminobutyric acid having L-configuration.
- 9.10 Purification Methods
- Crystallise butyrine from aqueous EtOH, and the melting point depends on heating rate but has m 303o in a sealed tube. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 2399 IR: 2401 1961, Beilstein 4 III 1294, 4 IV 2584.]
10. Computational chemical data
- Molecular Weight: 103.12g/mol
- Molecular Formula: C4H9NO2
- Compound Is Canonicalized: True
- XLogP3-AA: null
- Exact Mass: 103.063328530
- Monoisotopic Mass: 103.063328530
- Complexity: 72.1
- Rotatable Bond Count: 2
- Hydrogen Bond Donor Count: 2
- Hydrogen Bond Acceptor Count: 3
- Topological Polar Surface Area: 63.3
- Heavy Atom Count: 7
- Defined Atom Stereocenter Count: 1
- Undefined Atom Stereocenter Count: 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Isotope Atom Count: 0
- Covalently-Bonded Unit Count: 1
- CACTVS Substructure Key Fingerprint: AAADccBiMAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAHgAQCAAACCjBgAQCCABAAgAIAACQCAAAAAAAAAAAAIGAAAACABAAAAAAQAAEEAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA==
11. Recommended Suppliers
-
- Products:Cosmetic Raw Materials,solvents,etc.
- Tel:86-311-66562153
- Email:breeduan@crovellbio.com
-
- Products:pmk powder ;pmk oil ;bmk powder ;bmk oil ;Protonitazene hcl ; Bromazolam ; Metonitazene; 2-Bromo-4'-methylpropiophenone ;
- Tel:+86-180-32431584
- Email:amy@chbbest.com
-
- Products:API,fine chemical&its intermediates,biological chemistry
- Tel:0086-27-59207850
- Email:info@fortunachem.com
-
- Products:Pharmaceutical Intermediate , Apis , Food Additives , Herbal Extracts , Fine Chemicals , ...
- Tel:00-86-13023277276
- Email:hanna@xljxcl.com
-
- Products:Manufacture & Supply Biopharm Chemical, Specialty Chemical, PetroChemical.
- Tel:86-592-8883942
- Email:sale@amitychem.com
12. Realated Product Infomation
-120YR
skype
