Guidechem | China Chemical Manufacturers,suppliers,B2B Marketplace
Encyclop..
  • Products
  • Encyclopedia
  • Buy offers
  • Suppliers
Home> Encyclopedia >   /  Alkali  /  Other Inorganic Salts  /  Other Inorganic Chemicals
Magnesium hydroxide structure
Magnesium hydroxide structure

Magnesium hydroxide

Iupac Name:magnesium;dihydroxide
CAS No.: 1309-42-8
Molecular Weight:58.31970
Modify Date.: 2022-11-01 10:17
Introduction: Magnesium hydroxide is best known as the active ingredient in Milk of Magnesia, an antacid and laxative which has been used for 150 years. It forms a suspension in water, and its reaction with acid only dissolves it gradually, giving it long-lasting effects. At higher doses, rather than acid neutralization, its primary action is to hold water, as it is not absorbed by the large intestine, relieving constipation.It is also used as a fire retardant and smoke repressor in various applications due to an endothermic decomposition reaction which takes place at 332°C, releasing magnesia and water. Further applications include wastewater treatment, as a fuel additive, and production of magnesium salts. View more+
1. Names and Identifiers
1.1 Name
Magnesium hydroxide
1.2 Synonyms

EINECS 215-170-3 Magnesium hydrate,high purity flameretardant MAGNESIUM HYDROXIDE SIGMAULTRA Magnesium hydroxide, Ph.Eur.4, BP2001, USP24, E528 MAGNESIUM HYDROXIDE, POWDER Magnesium hyroxide usp25 magnesium,dihydroxide MFCD00011104

1.3 CAS No.
1309-42-8
1.4 CID
73981
1.5 EINECS(EC#)
215-170-3
1.6 Molecular Formula
H2MgO2 (isomer)
1.7 Inchi
InChI=1S/Mg.2H2O/h;2*1H2/q+2;;/p-2
1.8 InChkey
VTHJTEIRLNZDEV-UHFFFAOYSA-L
1.9 Canonical Smiles
[OH-].[OH-].[Mg+2]
1.10 Isomers Smiles
[OH-].[OH-].[Mg+2]
2. Properties
3.1 Density
2.36g/cm3
3.1 Melting point
350ºC ( Decomposes)
3.1 Boiling point
100ºC at 760mmHg
3.1 Refractive index
Index of refraction: 1.559, 1.580
3.1 Flash Point
will not burn
3.1 Precise Quality
57.99050
3.1 PSA
40.46000
3.1 logP
-0.35360
3.1 Solubility
5 M HCl: 0.1?M, clear, yellow
3.2 Appearance
odourless white powder
3.3 Storage
Air Sensitive. Store under Argon. Ambient temperatures.
3.4 Chemical Properties
Magnesium hydroxide is a white to off-white crystalline powder with a specific gravity of 2.4 and a Mohs hardness of around 3.0. It loses 30.9% of its mass as water vapor on heating above 450°C. It being soluble in dilute acid and ammonium salt solution, but almost insoluble in water and alcohol. The solubility in water (18 ° C) was 0.0009g/100g.
3.5 Color/Form
Amorphous powder
White, hexagonal crystals
Granules
3.6 Odor
Odorless
3.7 PH
pH = 9.5-10.5 (aqueous slurry)
3.8 Water Solubility
5 M HCl: 0.1?M, clear, yellow | 0.9 mg/100 mL (18 oC)
3.9 Spectral Properties
Index of refraction: 1.559, 1.580
3.10 Stability
Stable.
3. Use and Manufacturing
4.1 Definition
ChEBI: A magnesium hydroxide in which the magnesium atom is bound to two hydroxide groups.
4.2 Usage
Magnesium hydroxide is an excellent flame retardant for plastics and rubber products. In environmental protection, it can be used as flue gas desulfurization agent, being able to replace the caustic soda and lime as acid-containing waste water neutralizer. It can also used as oil additive with anti-corrosion and desulfurization effect. In addition, it can also be used for the electronics industry, medicine, sugar refining, for insulation materials and the manufacture of other magnesium salt products.One important application of Magnesium Hydroxide is the use of the material in the pharmaceutical industry, for example as antacid to neutralize stomach acids and as laxative.The largest industrial application of Magnesium Hydroxide is flame retardants for articles such as roofing, isolation materials, plastic articles and coatings. The mechanism of flame retardancy is based on the endothermic decomposition of the material into MgO and H2O. This reaction adsorbs heat, which delays ignition of the associated substance. The water that is released dilutes combustible gases and inhibits oxygen from aiding the combustion.
4. Safety and Handling
5.1 Symbol
GHS07
5.1 Hazard Codes
Xi
5.1 Signal Word
Warning
5.1 Risk Statements
R36/37/38
5.1 Safety Statements
S26; S36; S37/39
5.1 Exposure Standards and Regulations
Antacid products for over-the-counter (OTC) human use. Magnesium hydroxide is included on this list of specific active ingredients.
5.2 Hazard Declaration
H315-H319-H335
5.2 DisposalMethods
SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
5.3 RIDADR
50kgs
5.3 Safety Profile
Moderately toxic by intraperitoneal route. Human systemic effects: chlorine level changes, coma, somnolence. Incompatible with maleic anhydride, phosphorus. See also MAGNESIUM COMPOUNDS.
5.4 Caution Statement
P261-P305 + P351 + P338
5.4 Formulations/Preparations
MILK OF MAGNESIA USP, IS AN AQUEOUS SUSPENSION OF MAGNESIUM HYDROXIDE CONTAINING 7.0-8.5% OF MG(OH)2. EACH MILLILITER IS CAPABLE OF NEUTRALIZING APPROX 2.7 MEQ OF ACID. ...MAGNESIUM HYDROXIDE IS ALSO AVAIL AS MAGNESIA TABLETS...GENERALLY CONTAIN 325 MG EACH, WHICH CAN NEUTRALIZE 11.2 MEQ OF ACID.
USP; 250 ML & 500 ML BOTTLES WITH ALUMINUM HYDROXIDE GEL; 250 ML, 375 ML, 500 ML & 1 L BOTTLES.
SUSPENSION OF 30% MAGNESIUM HYDROXIDE IN WATER: HYDRO-MAGMA.
MAGNESIUM HYDROXIDE DRUG AVAILABLE GENERICALLY: POWDER; TABLETS 300 & 600 MG.
VET: PRIMARILY IN LAXATIVE MIXTURES FOR SUSPENSION IN LARGE QUANTITIES OF WATER, OCCASIONALLY IN BOLUS, & OCCASIONALLY AS MILK OF MAGNESIA; MAGMA MAGNESII, CREAM OF MAGNESIA, MIXTURE OF MAGNESIUM HYDROXIDE, & MISTURA MAGNESII HYDROXIDI (APPROX AN 8% AQUEOUS SOLUTION).
MAGNESIUM HYDROXIDE IS USUALLY MARKETED IN COMBINATION WITH OTHER ANTACIDS.
GRADES: TECHNICAL, NF, FCC.
VET: MAGNALOX BOLUSES, EACH BOLUS CONTAINS: MAGNESIUM HYDROXIDE 27 G; GINGER 200 MG, & CAPSICUM 50 MG.
A mixture of salts, available as Maalox, Mylanta, Gelusil, and Aludrox, contains magnesium hydroxide, Mg(OH)2, and variable amounts of aluminum oxide in the form of aluminum hydroxide and hydrated aluminum oxide, ie, 2.9-4.2% magnesium hydroxide and 2.0-2.4% aluminum oxide, Al2O3, for a mixture of 4.9-6.6% combined magnesium hydroxide and aluminum oxide. This mixture may contain a flavoring and antimicrobial agents in a total amount not to exceed 0.5% ... .
5.5 WGK Germany
-
5.5 RTECS
OM3570000
5.5 Reactivities and Incompatibilities
Phosphorus boiled with alkaline hydroxides yields mixed phosphines which may ignite spontaneously in air. /Alkaline hydroxides/
ALKALI & OTHER ALKALINE EARTH COMPD...MAGNESIUM COMPD...CAUSE EXPLOSIVE DECOMP OF MALEIC ANHYDRIDE.
5.6 Toxicity
LD50 oral in rat: 8500mg/kg
5. MSDS

2.Hazard identification

2.1 Classification of the substance or mixture

Not classified.

2.2 GHS label elements, including precautionary statements

Pictogram(s) No symbol.
Signal word

No signal word.

Hazard statement(s)

none

Precautionary statement(s)
Prevention

none

Response

none

Storage

none

Disposal

none

2.3 Other hazards which do not result in classification

none

6. Synthesis Route
7. Precursor and Product
precursor:
80937-33-3
80937-33-3
8. Other Information
8.0 Merck
14,5670
8.1 Description
Magnesium hydroxide is best known as the active ingredient in Milk of Magnesia, an antacid and laxative which has been used for 150 years. It forms a suspension in water, and its reaction with acid only dissolves it gradually, giving it long-lasting effects. At higher doses, rather than acid neutralization, its primary action is to hold water, as it is not absorbed by the large intestine, relieving constipation.
It is also used as a fire retardant and smoke repressor in various applications due to an endothermic decomposition reaction which takes place at 332°C, releasing magnesia and water. Further applications include wastewater treatment, as a fuel additive, and production of magnesium salts.
8.2 Chemical properties
It appears as white crystals or powder, being soluble in dilute acid and ammonium salt solution, but almost insoluble in water and alcohol. The solubility in water (18 ° C) was 0.0009 g/100 g.
8.3 antacids
Antacids are drugs that reduce the acidity of the gastric juice. Antacids can be used for the treatment of hyperacidity, gastric and duodenal ulcers. The ideal antacid should have strong anti-acid and long-term effect. Moreover, it is preferably that it doesn’t generate carbon dioxide during the neutralization of gastric acid and is not absorbed by the digestive tract. Even if absorbed, it should be harmless. The antacid, based on whether it can be absorbed by the digestive tract, is divided into absorbent antacids and non-absorbable antacids.
Magnesium hydroxide is a kind of non-absorption of antacid. This kind of drugs is not absorbed at all or only absorbed of a small amount by the digestive tract, thus having no systemic effects. Magnesium hydroxide has an effect similar to that of magnesium oxide. Its reaction with hydrochloric acid is slow and lasting effect. The fraction that is not reacted with hydrochloric acid can stay in the stomach for further reaction with the new secreted hydrochloric acid. It has similar laxative effect as the magnesium oxide.
8.4 Side Effects
Treatment of gastric acid with magnesium hydroxide, the following Side effects that you should report to your doctor or health care professional as soon as possible:
allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue
confusion
feeling faint or lightheaded, falls
loss of appetite
nausea, vomiting
rectal bleeding
unusually weak or tired
Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):
chalky taste
diarrhea
stomach cramps
8.5 Uses
1,In medicine, it can be used as antacids and laxatives, can also be used for manufacturing of sugar and magnesium oxide and so on
2,Magnesium hydroxide is an excellent flame retardant for plastics and rubber products. In environmental protection, it can be used as flue gas desulfurization agent, being able to replace the caustic soda and lime as acid-containing waste water neutralizer. It can also used as oil additive with anti-corrosion and desulfurization effect. In addition, it can also be used for the electronics industry, medicine, sugar refining, for insulation materials and the manufacture of other magnesium salt products.
3,For sugar refining, pharmaceutical industry;
4,Used as analytical reagents, but also for the pharmaceutical industry
Mainly used as flame retardant.
8.6 Sources
http://magnesiaspecialties.com/magnesia-product-forms-and-their-applications/
https://www.flinnsci.com/api/library/Download/a4c91d864e3e47f3b213a523ef2d55c4
https://en.wikipedia.org/wiki/Magnesium_hydroxide
8.7 Chemical Properties
Magnesium hydroxide, Mg(OHn, also known as magnesium hydrate and brucite, is a white powder that is very slightly soluble in water. It decomposes at 350°C (662 OF). It is used in the extraction of magnesium metal and as a reagent in the sulfite wood pulp process. Magnesium hydroxide is formed by the reaction of sodium hydroxide and a soluble magnesium salt solution. Brucite, a mineral composed of magnesium hydroxide with occasional traces of iron and manganese, is a white to grayish translucent secondary mineral found with serpentine and metamorphic dolomites.
8.8 Uses
Antacid; osmotic laxative.
8.9 Uses
Magnesium Hydroxide is an alkali that is a general purpose food additive. it exists as a white powder and has poor solubility in water and in alcohol. in frozen desserts it will increase the tendency for fat globules to clump, which results in an increase in dryness. it reacts with triglycerides in fatty acids to form soaps. it also functions as a drying agent in foods.
8.10 Definition
ChEBI: A magnesium hydroxide in which the magnesium atom is bound to two hydroxide groups.
8.11 Brand name
Oxaine M (Wyeth-Ayerst); Phillips Magnesia Tablets (Sterling Health U.S.A.); Phillips Milk of Magnesia Liquid (Sterling Health U.S.A.).
8.12 Safety Profile
Moderately toxic by intraperitoneal route. Human systemic effects: chlorine level changes, coma, somnolence. Incompatible with maleic anhydride, phosphorus. See also MAGNESIUM COMPOUNDS.
8.13 Usage
It is employed as an additive in certain refractories. It is applied as a non-hazardous alkali in neutralizing acidic wastewater. It is also used in making artificial reefs. It widely used in milk of magnesia antacids and laxatives. Also works as an antiperspirant.
8.14 Description
Magnesium hydroxide is best known as the active ingredient in Milk of Magnesia, an antacid and laxative which has been used for 150 years. It forms a suspension in water, and its reaction with acid only dissolves it gradually, giving it long-lasting effects. At higher doses, rather than acid neutralization, its primary action is to hold water, as it is not absorbed by the large intestine, relieving constipation.
It is also used as a fire retardant and smoke repressor in various applications due to an endothermic decomposition reaction which takes place at 332°C, releasing magnesia and water. Further applications include wastewater treatment, as a fuel additive, and production of magnesium salts.
8.15 Chemical properties
Magnesium hydroxide is a white to off-white crystalline powder with a specific gravity of 2.4 and a Mohs hardness of around 3.0. It loses 30.9% of its mass as water vapor on heating above 450°C. It being soluble in dilute acid and ammonium salt solution, but almost insoluble in water and alcohol. The solubility in water (18 ° C) was 0.0009g/100g.
Magnesium hydroxide
Magnesium hydroxide is used as highly effective non-toxic inorganic flame retardant, filler, and smoke suppressant additive for production of plastics and filled (co)polymer compounds based on elastomers, thermosets, thermoplastics, including those based on polyvinylchloride, polyamides, polystyrene, polyethylene, polypropylene, polyethylene terephthalate, ultrathene, and so on, in paper and cardboard industry, as a mild neutralizing agent for waste and natural water treatment, as raw material in chemical and pharmaceutical industry.
8.16 Uses
Magnesium hydroxide is an excellent flame retardant for plastics and rubber products. In environmental protection, it can be used as flue gas desulfurization agent, being able to replace the caustic soda and lime as acid-containing waste water neutralizer. It can also used as oil additive with anti-corrosion and desulfurization effect. In addition, it can also be used for the electronics industry, medicine, sugar refining, for insulation materials and the manufacture of other magnesium salt products.
One important application of Magnesium Hydroxide is the use of the material in the pharmaceutical industry, for example as antacid to neutralize stomach acids and as laxative.
The largest industrial application of Magnesium Hydroxide is flame retardants for articles such as roofing, isolation materials, plastic articles and coatings. The mechanism of flame retardancy is based on the endothermic decomposition of the material into MgO and H2O. This reaction adsorbs heat, which delays ignition of the associated substance. The water that is released dilutes combustible gases and inhibits oxygen from aiding the combustion.
8.17 Description
A white, bulky powder. It dissolves in dilute acids, but is practically insoluble in water and in alcohol.
8.18 Chemical Properties
Magnesium hydroxide is another metal hydrate that decomposes endothermically, accompanied by the formation of water. It decomposes at 330 °C, which is 100 °C higher than alumina trihydrate, and can therefore be used in polymers that are processed at higher temperatures. Magnesium hydroxide is white, has an average particle size of 1–10 μm, density of 2.36 g/mL, refractive index of 1.58, and Mohs’ hardness of 2.00. Water loss on ignition is 31.8 wt %. Magnesium hydroxide contains 1.0 wt % Ca(OH)2 and is made by Solem Industries and Morton Thiokol.
8.19 Chemical Properties
Magnesium hydroxide, Mg(OHn, also known as magnesium hydrate and brucite, is a white powder that is very slightly soluble in water. It decomposes at 350°C (662 OF). It is used in the extraction of magnesium metal and as a reagent in the sulfite wood pulp process. Magnesium hydroxide is formed by the reaction of sodium hydroxide and a soluble magnesium salt solution. Brucite, a mineral composed of magnesium hydroxide with occasional traces of iron and manganese, is a white to grayish translucent secondary mineral found with serpentine and metamorphic dolomites.
8.20 Physical properties
Magnesium Hydroxide decomposes when heated to 360°C and forms the oxide, MgO. It is very slightly soluble in water at 0.00122 g/100 ml and has a solubility product of 5.61×10-12. Crystals of Mg(OH)2 have a refractive index of 1.559. Its heat of formation is –925 kJ/mol with an entropy of 63 J/mol·K.
As a suspension in water, it is often called milk of magnesia because of its milk-like appearance. The solid mineral form of magnesium hydroxide is known as “brucite”.
It can be prepared by the metathesis reaction between any soluble magnesium salts and an alkali hydroxide such as sodium or even ammonium:
Mg2+(aq)+2OH-(aq)→Mg(OH)2(solid)
Magnesium hydroxide is a common component of antacids and laxatives. It interferes with the absorption of folic acid and iron. Its low solubility makes it a weak base. Another method of commercial manufacture of magnesium hydroxide involves the chloride obtained from seawater. After the chloride is recrystallized several times to obtain a level of purity, it is calcined at about 1000°C:
MgCl2·6H2O → MgCl2+6H2O
→ Mg(OH)-xCl2-x+xHCl
→ MgO+(2-x)HCl
8.21 Occurrence
Magnesium Hydroxide occurs naturally as the mineral brucite. Brucite, usually found as a low temperature, hydrothermal vein mineral associated with calcite, aragonite, talc, or magnesite, appears as a decomposition product of magnesium silicates associated with serpentine, dolomite, magnesite, and chromite. Brucite also occurs as a hydrated form of periclase, and is found in serpentine, marble, chlorite schists, and in crystalline limestone.
8.22 Uses
Magnesium hydroxide has been used in the synthesis of brucite.
9. Computational chemical data
  • Molecular Weight: 58.31970g/mol
  • Molecular Formula: H2MgO2
  • Compound Is Canonicalized: True
  • XLogP3-AA: null
  • Exact Mass: 57.9905210
  • Monoisotopic Mass: 57.9905210
  • Complexity: 0
  • Rotatable Bond Count: 0
  • Hydrogen Bond Donor Count: 2
  • Hydrogen Bond Acceptor Count: 2
  • Topological Polar Surface Area: 2
  • Heavy Atom Count: 3
  • Defined Atom Stereocenter Count: 0
  • Undefined Atom Stereocenter Count: 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Isotope Atom Count: 0
  • Covalently-Bonded Unit Count: 3
  • CACTVS Substructure Key Fingerprint: AAADcQAAMAAAACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAACAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA==
10. Recommended Suppliers
Global409SuppliersView all >>
  • Products:biotechnology pharmaceutical intermediates biotechnology medical intermediates
  • Tel:0086-0310-15343106358
  • Email:guide@cnyouze.com
Magnesium Dihydroxide CAS 1309-42-8 Magnesium hydrate
  • Purity:99%Packing: 200kg/bag FOB
  • Price: 8 USD/kg
  • Time: 2022/11/25
Inquire
  • Products:API,fine chemical&its intermediates,biological chemistry
  • Tel:0086-27-59207850
  • Email:info@fortunachem.com
Pharma grade Magnesium hydroxide CAS 1309-42-8 with factory price
  • Purity:99%Packing: 200kg/bag FOB
  • Price: 80 USD/kilogram
  • Time: 2022/11/24
Inquire
  • Products:Cosmetic Raw Materials,solvents,etc.
  • Tel:86-311-66562153
  • Email:breeduan@crovellbio.com
Factory Supply High purity fine Magnesium Hydroxide Powder 1309-42-8
  • Purity:99%Packing: 200kg/bag FOB
  • Price: 1 USD/kilogram
  • Time: 2022/11/08
Inquire
  • Products:Division I, the main production Lead acetate phenylacetamide Cyromazine quality is very good!
  • Tel:86-156-33831222
  • Email:xing@yan-xi.com
Ceramic pigment industry alumina powder cas 1309-42-8
  • Purity:99%Packing: 200kg/bag FOB
  • Price: 1 USD/kilogram
  • Time: 2022/08/24
Inquire
  • Products:Manufacture & Supply Biopharm Chemical, Specialty Chemical, PetroChemical.
  • Tel:86-592-8883942
  • Email:sale@amitychem.com
Factory Supply Magnesium hydroxide
  • Purity:99%Packing: 200kg/bag FOB
  • Price: 0.1 USD/kilogram
  • Time: 2022/07/07
Inquire
11. Realated Product Infomation