Mesterolone

(1a,5a,17b)-17-Hydroxy-1-methylandrostan-3-one (1S,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-1,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one (1α,5α,17Β)-17-Hydroxy-1-methylandrostan-3-one 17b-Hydroxy-1a-methyl-5a-androstan-3-one 17Β-Hydroxy-1α-methyl-5α-androstan-3-one 1-alpha-methyl-5-alpha-androstan-17-beta-ol-3-one 1a-Methyl-5a-androstan-17b-ol-3-one 1a-Methyl-5a-dihydrotestosterone 1α-Methyl-5α-dihydrotestosterone 1α-Methylandrostan-17Β-ol-3-one 4,5a-Dihydro-1a-methyltestosterone 5α-Androstan-3-one, 17Β-hydroxy-1α-methyl- Acetonitrile (test Mesterolone, 1.0 mg/mL) Androstan-3-one, 17-hydroxy-1-methyl-, (1α,5α,17Β)- androviron EINECS 215-836-3 mesteranum mesterolon Mesterolone (CIII) mesterolone--deascheduleiii mestoranum MFCD00133082 Proviron

The?Mesterolone is an orally applicable androgen, and DHT derivative.?The IUPAC name of this chemical is?(1S,5S,8R,9S,10S,13S,14S,17S)-17-hydroxy-1,10,13-trimethyl-1,2,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-one. With the?CAS registry number 1424-00-6,?it is also named as 1-alpha-Methyl-17-beta-hydroxy-5-alpha-androstan-3-one.?The product's categories?are?biochemistry; hydroxyketosteroids; steroids. Additionally, it is sold under the brand name Proviron, by Schering.?Furthermore,?Mesterolone is used?for the treatment of male hypogonadism and sperm infertility.

The other characteristics of this product can be summarized as:?(1)ACD/LogP: 4.24; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 4.24; (4)ACD/LogD (pH 7.4): 4.24; (5)ACD/BCF (pH 5.5): 988.22; (6)ACD/BCF (pH 7.4): 988.22; (7)ACD/KOC (pH 5.5): 4845.24; (8)ACD/KOC (pH 7.4): 4845.24; (9)#H bond acceptors: 2; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 1; (12)Index of Refraction: 1.525; (13)Molar Refractivity: 88.2 cm³; (14)Molar Volume: 287.6 cm³; (15)Polarizability: 34.96×10^-24 cm³; (16)Surface Tension: 38.3 dyne/cm; (17)Enthalpy of Vaporization: 77.87 kJ/mol; (18)Vapour Pressure: 7.98E-09 mmHg at 25°C; (19)Tautomer Count: 3; (20)Exact Mass: 304.24023; (21)MonoIsotopic Mass: 304.24023; (22)Topological Polar Surface Area: 37.3; (23)Heavy Atom Count: 22; (24)Complexity: 486.

When you are using this chemical, please be cautious about it as the following:
It is harmful by inhalation, in contact with skin and if swallowed. so people should?not breathe dust and avoid contact with skin and eyes.?If you want to contact this product, you must wear suitable protective clothing, gloves and eye/face protection.

People can use the following data to convert to the molecule structure.
1. SMILES:O=C4C[C@@H]3CC[C@@H]2[C@H](CC[C@]1(C)[C@@H](O)CC[C@H]12)[C@@]3(C)[C@@H](C)C4
2.?InChI:InChI=1/C20H32O2/c1-12-10-14(21)11-13-4-5-15-16-6-7-18(22)19(16,2)9-8-17(15)20(12,13)3/h12-13,15-18,22H,4-11H2,1-3H3/t12-,13-,15-,16-,17-,18-,19-,20-/m0/s1.

CHEMICAL IDENTIFICATION

RTECS NUMBER :

BV8063400

CHEMICAL NAME :

5-alpha-Androstan-3-one, 17-beta-hydroxy-1-alpha-methyl-

CAS REGISTRY NUMBER :

1424-00-6

LAST UPDATED :

198910

DATA ITEMS CITED :

1

MOLECULAR FORMULA :

C20-H32-O2

MOLECULAR WEIGHT :

304.52

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Subcutaneous

DOSE :

600 ug/kg

SEX/DURATION :

female 4 day(s) pre-mating

TOXIC EFFECTS :

Reproductive - Fertility - other measures of fertility

REFERENCE :

ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 16,455,1966