Methenolone acetate

(5α,17β)-17-(Acetyloxy)-1-methylandrost-1-en-3-one 17-(acetyloxy)-1-methyl-,(5-alpha,17-beta)-androst-1-en-3-on 17-beta-hydroxy-1-methyl-5-alpha-androst-1-en-3-onacetate 17-beta-hydroxy-1-methyl-5-alpha-androst-1-en-3-oneacetate 17b-Hydroxy-1-methyl-5a-androst-1-en-3-one acetate 17β-Hydroxy-1-methyl-5α-androst-1-en-3-one acetate 1-Methyl-17b-hydroxy-5a-androst-1-en-3-one acetate 1-Methyl-17β-hydroxy-5α-androst-1-en-3-one acetate 1-Methyl-17β-hydroxy-5α-androst-1-en-3-one-17β-acetate 1-Methyl-5α-androst-1-en-17β-ol-3-one acetate 5α-Androst-1-en-3-one, 17β-hydroxy-1-methyl-, acetate Androst-1-en-3-one, 17-(acetyloxy)-1-methyl-, (5α,17β)- METENOLONE ACETATE Methenolone 17-acetate METHENOLONE ACETATE nibal NSC 74226 Primobolan Primobolan Tablets Primobolone Primonabol SH 567 SH 567a SQ 16496

The Methenolone acetate has the cas register number 434-05-9, and it has the systematic name of (5alpha)-1-methyl-3-oxoandrost-1-en-17-yl acetate. This chemical is a kind of white or almost white crystalline powder. Besides, its product categories are including steroids.

The characteristics of this chemical are as follows: (1)ACD/LogP: 4.93; (2)ACD/LogD (pH 5.5): 4.92; (3)ACD/LogD (pH 7.4): 4.92; (4)ACD/BCF (pH 5.5): 3258.08; (5)ACD/BCF (pH 7.4): 3258.08; (6)ACD/KOC (pH 5.5): 11380.8; (7)ACD/KOC (pH 7.4): 11380.8; (8)#H bond acceptors: 3; (9)#Freely Rotating Bonds: 2; (10)Polar Surface Area: 43.37; (11)Index of Refraction: 1.536; (12)Molar Refractivity: 97.3 cm³; (13)Molar Volume: 311.8 cm³; (14)Polarizability: 38.57×10^-24 cm³; (15)Surface Tension: 41.2 dyne/cm; (16)Density: 1.1 g/cm³; (17)Flash Point: 189.9 °C; (18)Enthalpy of Vaporization: 69.85 kJ/mol; (19)Boiling Point: 441.2 °C at 760 mmHg; (20)Vapour Pressure: 5.54E-08 mmHg at 25°C; (21)Exact Mass: 344.235145; (22)MonoIsotopic Mass: 344.235145; (23)Topological Polar Surface Area: 43.4; (24)Heavy Atom Count: 25; (25)Complexity: 635.

In addition, you could obtain the molecular structure by converting the following datas:
(1)SMILES:CC(=O)OC1CC[C@H]2[C@@H]3CC[C@H]4CC(=O)\C=C(\C)[C@]4(C)[C@H]3CC[C@]12CCopyCopied
(2)InChI:InChI=1/C22H32O3/c1-13-11-16(24)12-15-5-6-17-18-7-8-20(25-14(2)23)21(18,3)10-9-19(17)22(13,15)4/h11,15,17-20H,5-10,12H2,1-4H3/t15-,17-,18-,19-,20?,21-,22-/m0/s1

Below are the toxicity information of this chemical:

CHEMICAL IDENTIFICATION

RTECS NUMBER :

BV8408500

CHEMICAL NAME :

5-alpha-Androst-1-en-3-one, 17-beta-hydroxy-1-methyl-, acetate

CAS REGISTRY NUMBER :

434-05-9

LAST UPDATED :

199309

DATA ITEMS CITED :

5

MOLECULAR FORMULA :

C22-H32-O3

MOLECULAR WEIGHT :

344.54

WISWESSER LINE NOTATION :

L E5 B666 OV LUTJ A1 E1 FOV1 K1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

4 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,835,1982

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Oral

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

4 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,835,1982

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - mouse

DOSE/DURATION :

2 gm/kg

TOXIC EFFECTS :

Details of toxic effects not reported other than lethal dose value

REFERENCE :

NIIRDN Drugs in Japan (Ethical Drugs). (Yakugyo Jiho Co., Ltd., Tokyo, Japan) Volume(issue)/page/year: 6,835,1982 ** REPRODUCTIVE DATA **

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Oral

DOSE :

200 mg/kg

SEX/DURATION :

male 10 day(s) pre-mating

TOXIC EFFECTS :

Reproductive - Paternal Effects - prostate, seminal vesicle, Cowper's gland, accessory glands

REFERENCE :

ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 14,330,1964

TYPE OF TEST :

TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :

Subcutaneous

DOSE :

60 mg/kg

SEX/DURATION :

female 17-20 day(s) after conception

TOXIC EFFECTS :

Reproductive - Specific Developmental Abnormalities - urogenital system

REFERENCE :

AVBIB9 Advances in the Biosciences. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1967- Volume(issue)/page/year: 13,71,1974