Guidechem | China Chemical Manufacturers,suppliers,B2B Marketplace
Encyclop..
  • Products
  • Buy offers
  • Encyclopedia
  • Suppliers
Home> Encyclopedia >   /  Organic Intermediates  /  Organic Intermediates  /  Other Chemicals  /  Pharmaceuticals and Biochemicals  /  Pharmaceuticals and Biochemicals
109384-19-2 structure

N-BOC-4-Hydroxypiperidine

Iupac Name:tert-butyl 4-hydroxypiperidine-1-carboxylate
CAS No.:109384-19-2
EINECS(EC#): 600-916-6
Molecular Weight:201.266
Molecular Formula:C10H19NO3 (isomer)
1. Names and Identifiers
1.1 Synonyms

1-(t-butyloxycarbonyl)-4-piperidinol 1-(tert-butoxycarbonyl)-4-hydroxypiperidine 1-(tert-Butoxycarbonyl)-4-hydroxypiperidine, tert-Butyl 4-hydroxypiperidine-1-carboxylate 1(tert-butoxycarbonyl)piperidin-4-ol 1-(tert-butoxycarbonyl)piperidine-4-ol 1-(tert-butyloxycarbonyl)-4-hydroxypiperidine 1-(tert-butyloxycarbonyl)-4-piperidinol 1-(tert-Butyloxycarbonyl)piperidin-4-ol 1,1-dimethylethyl 4-hydroxy-1-piperidinecarboxylate 1,1-dimethylethyl 4-hydroxypiperidinecarboxylate 1,1-Dimethylethyl4-hydroxypiperidine-1-carboxylate 1-Boc -4-hydroxypeiperidine 1-boc-4-hydroxy piperidine 1-boc-4-hydroxypiperidine 1-boc-4-hydroxy-piperidine 1-Boc-4-hydroxypiperidine ,98% 1-boc-4-hydroxypiperidine, 97% 1-boc-4-piperidinol 1-Boc-4-piperidinol, tert-Butyl 4-hydroxy-1-piperidinecarboxylate 1-boc-piperidin-4-ol 1-boc-piperidine-4-ol 1-n-boc-4-hydroxypiperdine 1-n-boc-4-hydroxy-piperidine 1-n-t-butyloxycarbonyl-4-hydroxypiperidine 1-piperidinecarboxylic acid, 4-hydroxy-, 1,1-dimethylethyl ester 1-Piperidinecarboxylicacid, 4-hydroxy-, 1,1-dimethylethyl ester 1-t-butoxycarbonyl-4-hydroxypiperidine 1-t-butoxycarbonyl-4-piperidinol 1-t-butoxycarbonylpiperidine-4-ol 1-t-butyloxycarbonylpiperidin-4-ol 1-tert-butoxycarbonyl-4-hydroxypiperidine 1-tert-butoxycarbonyl-4-hydroxy-piperidine 1-tert-butoxycarbonyl4-hydroxy-piperidine 1-tertbutoxycarbonyl-4-hydroxypiperidine 1-tert-butoxycarbonyl-4-piperidinol 1-tert-butoxycarbonylpiperidin-4-ol 1-tert-butoxycarbonylpiperidine-4-ol 1-tert-butyloxycarbonyl-4-hydroxypiperidine 1-tert-butyloxycarbonyl-4-hydroxy-piperidine 2-methylpropan-2-yl 4-hydroxypiperidine-1-carboxylate 4-Hydroxy-1-(tert-butoxycarbonyl)piperidine 4-hydroxy-1-bocpiperidine 4-hydroxy-1-boc-piperidine 4-hydroxy-1-piperidinecarboxylic acid tert-butyl ester 4-Hydroxy-1-piperidinecarboxylicacid tert-butyl ester 4-hydroxy-1-t-butoxycarbonylpiperidine 4-hydroxy-1-tert-butoxycarbonylpiperidine 4-hydroxy-boc-piperidine 4-hydroxy-n-(t-butoxycarbonyl)piperidine 4-Hydroxy-N-(tert-butoxycarbonyl)piperidine 4-hydroxy-n-boc piperidine 4-hydroxy-n-boc-piperidine 4-hydroxy-piperdine-1-carboxylic acid tert-butyl ester 4-hydroxy-piperidin-1-carboxylic acid tert-butyl ester 4-hydroxypiperidine, n-boc protected 4-hydroxypiperidine-1-carboxylic acid t-butyl ester 4-hydroxy-piperidine-1-carboxylic acid tert-butyl ester 4-hydroxy-piperidine-1-carboxylic acid tert-butyl-ester 4-Hydroxypiperidine-1-carboxylic acid tert-butylester 4-hydroxy-piperidine-1-carboxylic acid-tert-butylester 4-hydroxy-piperidine-1-carboxylic-acid tert-butyl ester 4-hydroxypiperidine-1-car-boxylic-acid-tert-butyl ester AB0001836 AB1001281 AC1LD7DG AC1Q1N1U AC-2551 AJ-10200 AKOS000499733 AMPD00092 AN-1358 ARONIS010264 AZ0001-0259 B2671 B50150 BBL029147 BC208967 BH561 boc-(4-hydroxy)piperidine boc-(4-hydroxy)-piperidine boc-4-hydroxypiperidine BR-17101 C2071 CB-266 CJ-00558 CS-M0052 DB-004069 DTXSID40349203 EBD2199053 EN300-27439 F3146-0160 FC0495 HMS1431M09 I12-0020 IDI1_011660 JSP000751 MAYBRIDGE3_000273 mfcd01075174 MOLPORT-000-001-532 N - bok - 4 - hydroxy piperidine n-(t-butoxycarbonyl)4-hydroxypiperidine n-(t-butoxycarbonyl)-4-piperidinol N-(tert-Butoxycarbonyl)-4-hydroxypiperidine n-(tert-butoxycarbonyl)-4-piperidinol n-(tert-butoxycarbonyl)-piperidin-4-ol n-(tert-butoxycarbonyl)-piperidin4-ol N-(tert-Butoxycarbonyl)piperidin-4-ol N-(tert-Butyloxycarbonyl)-4-hydroxypiperidine n-(tert-butyloxy-carbonyl)-4-piperidinol n-(tert-butyloxycarbonyl)-4-piperidinol n-boc 4-hydroxypiperidine n-boc 4-piperidinol N-Boc-4hydropiperidine n-boc-4-hydroxy piperidine N-Boc-4-hydroxy-1-piperidine n-boc-4-hydroxylpiperidine n-boc-4-hydroxy-piperidine n-boc4-hydroxypiperidine N-BOC-4-Hydroxypiperidine N-(tert-Butoxycarbonyl)-4-hydroxypiperidine N-BOC-4-Hydroxypiperidine,97% n-boc-4-piperidinol n-t-butoxycarbonyl-4-hydroxypiperidine n-tert-butoxycarbonyl 4-hydroxypiperidine n-tert-butoxycarbonyl-4-hydroxypiperidine n-tert-butoxycarbonyl-4-hydroxy-piperidine n-tert-butoxycarbonylpiperidin-4-ol n-tert-butyloxycarbonyl-4-piperidinol PS-5411 PWQLFIKTGRINFF-UHFFFAOYSA-N Q-101209 RARECHEM AH CK 0055 RP04313 RTC-062140 SC-00323 SCHEMBL47319 ST2413917 STL065851 SY001987 t-butyl 4-hydroxy-1-piperidinecarboxylate t-butyl 4-hydroxypiperidine-1-carboxylate t-butyl-4-hydroxy-1-piperidine carboxylate t-butyl-4-hydroxy-1-piperidinecarboxylate TC-062140 tert. butyl 4-hydroxypiperidine-1-carboxylate tert.butyl 4-hydroxypiperidine-1-carboxylate tert.butyl-4-hydroxypiperidine-1-carboxylate tert-butoxycarbonyl-4-hydroxypiperidine tert-butoxycarbonyl-4-hydroxy-piperidine tert-butoxycarbonylpiperidin-4-ol tert-butyl (4-hydroxy)-piperidine-1-carboxylate tert-butyl 4 hydroxypiperidine-1-carboxylate tert-butyl 4-(hydroxy)piperidin-1-carboxylate tert-butyl 4-hydroxy-1-piperdinecarboxylate tert-butyl 4-hydroxy-1-piperidine carboxylate TERT-BUTYL 4-HYDROXY-1-PIPERIDINECARBOXYLATE tert-butyl 4-hydroxy-1--piperidinecarboxylate tert-butyl 4-hydroxy-1-piperidine-carboxylate tert-butyl 4-hydroxypiperidin-1-carboxylate tert-butyl 4-hydroxypiperidin-1-ylcarboxylate tert-butyl 4-hydroxypiperidine carboxylate tert-butyl -4-hydroxypiperidine-1-carboxylate tert-butyl 4-hydroxy-piperidine-1-carboxylate tert-butyl 4-hydroxypiperidine-1-carboxylate tert-butyl 4-hydroxy-piperidinecarboxylate tert-butyl 4-hydroxytetrahydro-1(2h)-pyridinecarboxylate tert-butyl-4-hydroxy-1-piperidine carboxylate tert-butyl-4-hydroxy-1-piperidinecarboxylate tert-butyl-4-hydroxy-1-piperidine-carboxylate tert-Butyl4-hydroxy-1-piperidinecarboxylate tert-butyl-4-hydroxypiperidine-1-carboxylate tert-butyl4-hydroxypiperidine-1-carboxylate TL8000300 TRA0014652 VU0510739-1 ZB002548 ZINC66271

1.2 Inchi
InChI=1S/C10H19NO3/c1-10(2,3)14-9(13)11-6-4-8(12)5-7-11/h8,12H,4-7H2,1-3H3
1.3 InChkey
PWQLFIKTGRINFF-UHFFFAOYSA-N
1.4 Canonical Smiles
CC(C)(C)OC(=O)N1CCC(CC1)O
2. 3D Conformer
3. Properties
3.1 Appearance
white or off-white crystalline powder
3.2 Density
1.107
3.3 Melting Point
60-65℃
3.4 Boiling Point
292.3℃ at 760 mmHg
3.5 Vapour
0.000198mmHg at 25°C
3.6 Refractive Index
1.495
3.7 Flash Point
130.6℃
3.8 HS Code
29339900
3.9 Storage temp
Store at -15°C
4. Safety and Handling
4.1 Hazard Codes
Xi
4.2 Risk Statements
R36/37/38
4.3 Safety Statements
S26;S36;S37/39
4.4 HazardClass
IRRITANT
4.5 Safety

Hazard Codes:IrritantXi
Risk Statements: 36/37/38
R36/37/38: Irritating to eyes, respiratory system and skin
Safety Statements: 26;36;37/39
S26: In case of contact with eyes, rinse immediately with plenty of WATER and seek medical advice.
S36: Wear suitable protective clothing
S37/39: Wear suitable gloves and eye/face protection
WGK Germany: 3
Hazard Note: Irritant
HazardClass: IRRITANT

4.6 Cleanup Methods
Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.
4.6 Fire Fighting Procedures
Suitable extinguishing media
Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.
Special protective equipment for fire-fighters
Wear self contained breathing apparatus for fire fighting if necessary.
4.7 Specification

N-BOC-4-Hydroxypiperidine (CAS NO.109384-19-2) is also called as Tert-butyl 4-hydroxypiperidine-1-carboxylate ; Tert-butyl 4-hydroxy-1-piperidinecarboxylate ; N-(tert-butoxycarbonyl)-4-hydroxypiperidine ; N-(tert-butoxycarbonyl)-4-piperidinol ; N-boc-4-piperidinol ; N-boc-4-hydroxypiperidine ; N-boc-4-hydroxylpiperidine.

5. MSDS

2.Hazard identification

2.1 Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity \u2013 single exposure, Category 3

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word

Warning

Hazard statement(s)

H315 Causes skin irritation

H319 Causes serious eye irritation

H335 May cause respiratory irritation

Precautionary statement(s)
Prevention

P264 Wash ... thoroughly after handling.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P271 Use only outdoors or in a well-ventilated area.

Response

P302+P352 IF ON SKIN: Wash with plenty of water/...

P321 Specific treatment (see ... on this label).

P332+P313 If skin irritation occurs: Get medical advice/attention.

P362+P364 Take off contaminated clothing and wash it before reuse.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P337+P313 If eye irritation persists: Get medical advice/attention.

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P312 Call a POISON CENTER/doctor/\u2026if you feel unwell.

Storage

P403+P233 Store in a well-ventilated place. Keep container tightly closed.

P405 Store locked up.

Disposal

P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

9. Computational chemical data
  • Molecular Weight:201.266g/mol
  • Molecular Formula:C10H19NO3
  • Compound Is Canonicalized:True
  • Exact Mass:201.136
  • Monoisotopic Mass:201.136
  • Complexity:202
  • Rotatable Bond Count:2
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:3
  • Topological Polar Surface Area:49.8A^2
  • Heavy Atom Count:14
  • Defined Atom Stereocenter Count:0
  • Undefined Atom Stereocenter Count:0
  • Defined Bond Stereocenter Count:0
  • Undefined Bond Stereocenter Count:0
  • Isotope Atom Count:0
  • Covalently-Bonded Unit Count:1
  • CACTVS Substructure Key Fingerprint: AAADceByMAAAAAAAAAAAAAAAAAAAAAAAAAAsAAAAAAAAAAAAAAAAHgAACAAADFThgAYCCAMABgAI AAAAGAAAAAAAAAAAAAAIAAAAEAIAgAAMQAACBgCAAAAQAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA AA==
11. Recommended Suppliers
Global(316)Suppliers
Purity:99% Packing:proper packing FOB Price:0 USD/Kilogram Inquire
  • Products:Our company is an internationally oriented research based pharmaceutical company with headquarters located in Hangzhou,China.
  • Tel:86-571-87758773
  • Email:balas@utanpharma.com
Purity: Packing: Inquire
  • Products:Pharmaceutical intermediates
  • Tel:+86-25-83208295
  • Email:ben@ailybiotech.com
Purity:99+%min Packing:as customer’s request. FOB Price:1 USD/Kilogram Inquire
  • Products:Pharmaceutical raw materials,Chemical reagent, Food aditives,Plant ExtracPharmaceutical and pesticide intermediates.
  • Tel:86-431-81915458
  • Email:cathytan@jltely.com
Purity:99% Packing:barrel FOB Price:1 USD/Kilogram Inquire
  • Products:Division I, the main production Lead acetate phenylacetamide Cyromazine quality is very good!
  • Tel:86-311-66561638
  • Email:xing@yan-xi.com
Purity:98% Packing:500g Inquire
  • Products:API & API intermediates
  • Tel:86-21-33758180
  • Email:sales@dochemical.com
Purity:95%, 99% Packing:clients requirement FOB Price:2 USD/Kilogram Inquire
  • Products:Chemical products
  • Tel:86-571-88938639
  • Email:sales-gc@chinadayangchem.com
Purity:99%min Packing:125kg/drum FOB Price:1 USD/Kilogram Inquire
  • Products:pharmaceutical intermediates, biochemistry and customized chemicals, special chemicals, organic and inorganic chemicals, medical devices, electronic chemicals and biological sciences
  • Tel:+86-0592-5567629
  • Email:sales@chemzhongyuan.com
Purity:99% Packing:25KG/DRUM FOB Price:100 USD/Kilogram Inquire
  • Products:Veterinary products,Nutrition products,Agrochemicals,Active pharmaceutical Ingredients,Custom systhesis,Contract manufacturing
  • Tel:86-571-85829152
  • Email:market@royalpharms.com
  • Products:API
  • Tel:0086-27-59207850
  • Email:info@fortunachem.com
Purity:99.1%. Packing:50g;1kg;5kg Inquire
  • Products:bulk commodities, lab agents, intermediates & fragments, special chemicals, agro-chemicals, APIs, natural ingredients
  • Tel:86-25-83697070
  • Email:sales@chemlin.com.cn