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Home> Encyclopedia >Food Additives>Pharmaceutical Intermediates>Organic Intermediate
Ribose structure
Ribose structure

Ribose

Iupac Name:(2S,3S,4S)-2,3,4,5-tetrahydroxypentanal
CAS No.: 24259-59-4
Molecular Weight:150.13
Modify Date.: 2022-11-03 15:26
Introduction: It is produced by microorganism fermentation of glucose in a fermentation culture medium without adding calcium carbonate. View more+
1. Names and Identifiers
1.1 Name
Ribose
1.2 Synonyms

(2R,3S,4R,5S)-5-(hydroxymethyl)oxolane-2,3,4-triol (2S,3S,4S)-2,3,4,5-Tetrahydroxypentanal aldehydo-L-ribose L-(+)-Ribos L-(+)-Ribose l-[1-13C]ribose l-[UL-13C5]ribose L-D-Ribose L-Ribose Ribose, L-

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1.3 CAS No.
24259-59-4
1.4 CID
90428
1.5 EINECS(EC#)
246-110-4
1.6 Molecular Formula
C5H10O5 (isomer)
1.7 Inchi
InChI=1S/C5H10O5/c6-1-3(8)5(10)4(9)2-7/h1,3-5,7-10H,2H2/t3-,4+,5-/m1/s1
1.8 InChIkey
PYMYPHUHKUWMLA-MROZADKFSA-N
1.9 Canonical Smiles
C(C(C(C(C=O)O)O)O)O
1.10 Isomers Smiles
C([C@@H]([C@@H]([C@@H](C=O)O)O)O)O
2. Properties
2.1 Density
1.681
2.1 Melting point
81-84℃
2.1 Boiling point
331
2.1 Refractive index
20 ° (C=1, H2O)
2.1 Flash Point
180.8°C
2.1 Precise Quality
150.05300
2.1 PSA
97.99000
2.1 logP
-2.73970
2.1 Solubility
Soluble in water (100 mg/ml).
2.2 Appearance
White.
2.3 Storage
Hygroscopic. Ambient temperatures.
2.4 Chemical Properties
white crystals or powder
2.5 pKa
12.22(at 25℃)
2.6 Water Solubility
Very soluble
2.7 Stability
Stable. Combustible. Incompatible with strong oxidizing agents.
2.8 StorageTemp
2-8°C
3. Use and Manufacturing
3.1 Definition
A monosaccharide; a component of RNA.
3.2 Usage
It is produced by microorganism fermentation of glucose in a fermentation culture medium without adding calcium carbonate.
4. Safety and Handling
4.1 Hazard Codes
Xi
4.1 Risk Statements
R36/37/38
4.1 Safety Statements
S26;S36
4.1 WGK Germany
3
4.1 RTECS
246-110-4
4.1 Safety

Hazard Codes of L-Ribose (CAS NO.24259-59-4): IrritantXi
Risk Statements: 36/37/38 
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 24/25-36-26 
S24/25: Avoid contact with skin and eyes. 
S36: Wear suitable protective clothing. 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
WGK Germany: 3
F: 3-10

5. MSDS

2.Hazard identification

2.1 Classification of the substance or mixture

Not classified.

2.2 GHS label elements, including precautionary statements

Pictogram(s) No symbol.
Signal word

No signal word.

Hazard statement(s)

none

Precautionary statement(s)
Prevention

none

Response

none

Storage

none

Disposal

none

2.3 Other hazards which do not result in classification

none

8. Other Information
8.0 Usage
L-Ribose is a potential starting material for the synthesis of many L-nucleoside-based pharmaceutical compounds.
9. Computational chemical data
  • Molecular Weight: 150.13g/mol
  • Molecular Formula: C5H10O5
  • Compound Is Canonicalized: True
  • XLogP3-AA: null
  • Exact Mass: 150.05282342
  • Monoisotopic Mass: 150.05282342
  • Complexity: 104
  • Rotatable Bond Count: 4
  • Hydrogen Bond Donor Count: 4
  • Hydrogen Bond Acceptor Count: 5
  • Topological Polar Surface Area: 98
  • Heavy Atom Count: 10
  • Defined Atom Stereocenter Count: 3
  • Undefined Atom Stereocenter Count: 0
  • Defined Bond Stereocenter Count: 0
  • Undefined Bond Stereocenter Count: 0
  • Isotope Atom Count: 0
  • Covalently-Bonded Unit Count: 1
  • CACTVS Substructure Key Fingerprint: AAADccBgOAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAGgAACAAACBSggAIAAAAAAgAIAAgQgAIAAAAAAAAAAAFAAAABEBYAAAAAQAAFIAABAADKBAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA==
10. Question & Answer
  • Ribose (C5H10O5) is a typical pentose sugar that plays a crucial role in various nucleic acids (RNA), coenzymes such as nucleotide coenzymes, ATP, and NADP. It is closely related to biological inherit..
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