Guidechem | China Chemical Manufacturers,suppliers,B2B Marketplace
Encyclop..
  • Products
  • Encyclopedia
  • Buy offers
  • Suppliers
Home> Encyclopedia >   /  Organic Intermediate  /  Pharmaceutical Intermediates  /  Pharmaceutical  /  Organic Intermediates  /  Others
(S)-(+)-2-Amino-3-methyl-1-butanol structure
(S)-(+)-2-Amino-3-methyl-1-butanol structure

(S)-(+)-2-Amino-3-methyl-1-butanol

Iupac Name:(2S)-2-amino-3-methylbutan-1-ol
CAS No.:2026-48-4
Molecular Weight:103.16282
1. Names and Identifiers
1.1 Name
(S)-(+)-2-Amino-3-methyl-1-butanol
1.2 Synonyms

(+)-(S)-Valinol (+)-2-Amino-3-methyl-1-butanol (+)-L-VALINOL (+)-Valinol (2S)-1-Hydroxy-3-methylbutan-2-amine (2S)-2-Amino-3-methyl-1-butanol (2S)-Valinol (S)-(+)-2-Amino-3-methyl-1-butanol (S)-(+)-Valinol (S)-2-Amino-3-methyl-1-butanol (S)-2-Amino-3-methylbutanol (S)-Valinol [(S)-1-(Hydroxymethyl)-2-methylpropyl]amine 1-Butanol, 2-amino-3-methyl-, (2S)- 1-Butanol, 2-amino-3-methyl-, (S)- 1-Butanol, 2-amino-3-methyl-, L- H-VALINOL H-VAL-OL L-(+)-VALINOL L-2-AMINO-3-METHYL-1-BUTANOL l-2-amino-3-methylbutan-1-ol L-VALINAL L-VALINOL NSC 322922

1.3 CAS No.
2026-48-4
1.4 CID
640993
1.5 EINECS(EC#)
217-975-5
1.6 Molecular Formula
C5H13NO (isomer)
1.7 Inchi
InChI=1S/C5H13NO/c1-4(2)5(6)3-7/h4-5,7H,3,6H2,1-2H3/t5-/m1/s1
1.8 InChkey
NWYYWIJOWOLJNR-RXMQYKEDSA-N
1.9 Canonical Smiles
CC(C)C(CO)N
1.10 Isomers Smiles
CC(C)[C@@H](CO)N
2. Properties
3.1 Density
0.926
3.1 Melting point
30-32℃
3.1 Boiling point
81℃ (8 torr)
3.1 Refractive index
1.4538-1.4558
3.1 Flash Point
78℃
3.1 Vapour pressure
0.182mmHg at 25°C
3.1 Precise Quality
103.10000
3.1 PSA
46.25000
3.1 logP
0.66230
3.1 Appearance
white to light yellow crystal powder
3.2 Chemical Properties
white to light yellow crystal powde
3.3 Color/Form
Clear slightly yellow
3.4 pKa
12.82±0.10(Predicted)
3.5 Water Solubility
Very soluble
3.6 Stability
Stable under normal temperatures and pressures. Absorbs carbon dioxide from the air.
3.7 StorageTemp
2-8°C
3. Use and Manufacturing
4.1 Storage
Keep Cold. Air Sensitive.
4. Safety and Handling
5.1 Hazard Codes
Xi
5.1 Risk Statements
R36
5.1 Safety Statements
S24/25
5.1 Hazard Class
IRRITANT
5.1 WGK Germany
3
5.1 Safety

Hazard Codes:?IrritantXi
Risk Statements: 36-36/37/38?
R36:Irritating to eyes.?
R36/37/38:Irritating to eyes, respiratory system and skin.
Safety Statements: 26-24/25-36?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S24/25:Avoid contact with skin and eyes.?
S36:Wear suitable protective clothing.
WGK Germany: 3
F: 10-23
HazardClass: IRRITANT
HS Code: 29221980

5.2 Sensitive
Air Sensitive
5.3 Specification

?L-2-Amino-3-methylbutan-1-ol , its cas register number is 2026-48-4. It also can be called L-2-Amino-3-methylbutan-1-ol ; L-(+)-Valinol ; (S)-(+)-2-Amino-3-methyl-1-butanol ;?(2S)-2-Amino-3-methylbutan-1-ol ; 1-Butanol, 2-amino-3-methyl-, (S)- .It is a white to light yellow crystal powder.

5. MSDS

2.Hazard identification

2.1 Classification of the substance or mixture

Eye irritation, Category 2

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word

Warning

Hazard statement(s)

H319 Causes serious eye irritation

Precautionary statement(s)
Prevention

P264 Wash ... thoroughly after handling.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

Response

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P337+P313 If eye irritation persists: Get medical advice/attention.

Storage

none

Disposal

none

2.3 Other hazards which do not result in classification

none

9. Other Information
9.0 Usage
L-(+)-Valinol reacts with aldehydes and nitriles to form imines and oxazolines, respectively, for asymmetric synthesis. It is also used for preparation of 4-isopropyloxazolidinones, employed in stereocontrolled aldol and alkylation reactions, synthesis of chiral 2-thiazolidinethiones for aldol reactions, asymmetric alkylation of condensation product with keto acids, asymmetric reactions of its amidines and imines and oxidation of N-protected derivative to the aldehyde.
10. Computational chemical data
  • Molecular Weight:103.16282g/mol
  • Molecular Formula:C5H13NO
  • Compound Is Canonicalized:True
  • XLogP3-AA:0
  • Exact Mass:103.099714038
  • Monoisotopic Mass:103.099714038
  • Complexity:45.3
  • Rotatable Bond Count:2
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:2
  • Topological Polar Surface Area:46.2
  • Heavy Atom Count:7
  • Defined Atom Stereocenter Count:1
  • Undefined Atom Stereocenter Count:0
  • Defined Bond Stereocenter Count:0
  • Undefined Bond Stereocenter Count:0
  • Isotope Atom Count:0
  • Covalently-Bonded Unit Count:1
11. Recommended Suppliers
Global248SuppliersView all >>
  • Products:Cosmetic Raw Materials,solvents,etc.
  • Tel:86-311-66562153
  • Email:breeduan@crovellbio.com
(S)-(+)-2-Amino-3-methyl-1-butanol Cas 2026-48-4 from China
  • Purity:99%Packing: 200kg/bag FOB
  • Price: 10 USD/kilogram
  • Time: 2022/05/05
Inquire
  • Products:Cangzhou Enke Pharma-tech Co.,Ltd (China) is a leading manufacturer of innovative chemistry products and services throughout the pharmaceutical R&D process and commercial production.
  • Tel:0086-317-5296180
  • Email:sale@enkepharma.com
(S)-(+)-2-Amino-3-methyl-1-butanol
  • Purity:99%Packing: 200kg/bag FOB
  • Price: 111 USD/kilogram
  • Time: 2022/04/29
Inquire
  • Products:Division I, the main production Lead acetate phenylacetamide Cyromazine quality is very good!
  • Tel:86-311-66561638
  • Email:xing@yan-xi.com
(S)-(+)-2-Amino-3-methyl-1-butanol
  • Purity:99%Packing: 200kg/bag FOB
  • Price: 1 USD/kilogram
  • Time: 2022/05/19
Inquire
  • Products:Manufacture & Supply Biopharm Chemical, Specialty Chemical, PetroChemical.
  • Tel:86-592-8883942
  • Email:sale@amitychem.com
Factory Supply (S)-(+)-2-Amino-3-Methyl-1-Butanol
  • Purity:99%Packing: 200kg/bag FOB
  • Price: 0.1 USD/kilogram
  • Time: 2022/02/09
Inquire
  • Products:Chemical products
  • Tel:86-571-88938639
  • Email:sales-gc@chinadayangchem.com
L-Valinol
  • Purity:99%Packing: 200kg/bag FOB
  • Price: 1 USD/kilogram
  • Time: 2022/04/28
Inquire