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2 Hydroxybenzoic Acid 2-Hydroxybenzenecarboxylic acid 2-HYDROXYBENZOIC ACID 2-hydroxy-benzoic acid ACETYLSALICYLIC ACID IMPURITY C ACETYLSALISYLIC ACID IMP C Acid, 2-Hydroxybenzoic Acid, o-Hydroxybenzoic Acid, ortho-Hydroxybenzoic Acid, Salicylic ACIDUM SALICYLICUM Benzoic acid, 2-hydroxy- Benzoic acid, o-hydroxy- Duofilm Duoplant EINECS 200-712-3 FEMA 3985 Freezone Hydroxybenzenecarboxylic acid Ionil Keralyt Lamivudine Impurity 3 MFCD00002439 o-hydroxybenzoic acid ortho Hydroxybenzoic Acid ORTHO-HYDROXYBENZOIC ACID phenol-carboxylic acid RETARDER TSA Rutranex SALICYCLIC ACID Saligel Salonil SAX Stri-Dex Verrugon
Hazard Codes:?Xn
Risk Statements:? 22-41-36/37/38
22:? Harmful if swallowed?
41:? Risk of serious damage to eyes?
36/37/38:? Irritating to eyes, respiratory system and skin
Safety Statements:? 26-39-37/39-36
26:? In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
39:? Wear eye/face protection?
37/39:? Wear suitable gloves and eye/face protection?
36:? Wear suitable protective clothing
WGK Germany:? 1
HS Code: ?29182100
The chief derivative of Salicylic Acid (CAS NO.69-72-7), which is used as a drug, is the methyl acetyl ester, known as aspirin.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
cat | LD50 | oral | 400mg/kg (400mg/kg) | ? | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 148, 1959. |
mammal (species unspecified) | LC50 | inhalation | > 300mg/m3 (300mg/m3) | ? | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 57(7-8), Pg. 31, 1992. |
man | TDLo | skin | 57mg/kg (57mg/kg) | SENSE ORGANS AND SPECIAL SENSES: TINNITUS: EAR | JAMA, Journal of the American Medical Association. Vol. 244, Pg. 660, 1980. |
mouse | LD50 | intraperitoneal | 300mg/kg (300mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION |
Gendai no Rinsho. Vol. 3, Pg. 675, 1969. |
mouse | LD50 | intravenous | 184mg/kg (184mg/kg) | BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD | Yakugaku Zasshi. Journal of Pharmacy. Vol. 91, Pg. 550, 1971. |
mouse | LD50 | oral | 480mg/kg (480mg/kg) | ? | "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 148, 1959. |
mouse | LD60 | subcutaneous | 520mg/kg (520mg/kg) | CARDIAC: CHANGE IN RATE BEHAVIORAL: MUSCLE WEAKNESS |
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 38, Pg. 9, 1930. |
rabbit | LD50 | oral | 1300mg/kg (1300mg/kg) | ? | Drugs in Japan Vol. 6, Pg. 291, 1982. |
rabbit | LD50 | skin | > 10gm/kg (10000mg/kg) | ? | BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 21-3/1971, |
rabbit | LDLo | subcutaneous | 6gm/kg (6000mg/kg) | ? | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1392, 1935. |
rat | LC50 | inhalation | > 900mg/m3/1H (900mg/m3) | ? | BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 21-3/1971, |
rat | LD50 | intraperitoneal | 157mg/kg (157mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: TREMOR |
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 57(7-8), Pg. 31, 1992. |
rat | LD50 | oral | 891mg/kg (891mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: MUSCLE WEAKNESS |
BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 21-3/1971, |
rat | LD50 | skin | > 2gm/kg (2000mg/kg) | LIVER: OTHER CHANGES SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 15(Suppl, |
women | TDLo | skin | 111mg/kg/10D- (111mg/kg) | SENSE ORGANS AND SPECIAL SENSES: CHANGE IN ACUITY: EAR CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP |
Postgraduate Medical Journal. Vol. 70, Pg. 146, 1994. |
Acute toxicity - Oral, Category 4
Serious eye damage, Category 1
Pictogram(s) | ![]() ![]() |
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Signal word | Danger |
Hazard statement(s) | H302 Harmful if swallowed H318 Causes serious eye damage |
Precautionary statement(s) | |
Prevention | P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection. |
Response | P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/\u2026if you feel unwell. P330 Rinse mouth. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P310 Immediately call a POISON CENTER/doctor/\u2026 |
Storage | none |
Disposal | P501 Dispose of contents/container to ... |
none
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