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(-)-3,4,5-Trihydroxy-1-cyclohexene-1-carboxylic acid (-)-Shikimic acid (3R,4S,5R)-(-)-3,4,5-Trihydroxy-1-cyclohexene-1-carboxylic Acid (3R,4S,5R)-3,4,5-Trihydroxy-1-cyclohexene-1-carboxylic acid (3R,4S,5R)-3,4,5-TRIHYDROXY-1-CYCLOHEXENECARBOXYLIC ACID (3R,4S,5R)-3,4,5-TRIHYDROXY-CYCLOHEX-1-ENECARBOXYLIC ACID [3R-(3α,4α,5β)]-3,4,5-Trihydroxy-1-cyclohexene-1-carboxylic acid 1-Cyclohexene-1-carboxylic acid, 3,4,5-trihydroxy-, (3R,4S,5R)- 1-Cyclohexene-1-carboxylic acid, 3,4,5-trihydroxy-, [3R-(3α,4α,5β)]- 3,4,5-Trihydroxy-1-cyclohexene-1-carboxylic acid 3,4,5-Trihydroxycyclohex-1-enecarboxylic acid Illicium Verum P.E. L-SHIKIMIC ACID NSC 59257 Shikimic acid methyl esther Shikimic acid,(3R,4S,5R)-()-3,4,5-Trihydroxy-1-cyclohexenecarboxylic acid
IARC Cancer Review: Group 3 IMEMDT?. IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.:?) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 40 ,1986,p. 47.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.:?) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.
?Shikimic acid's safety information: Moderately toxic by intraperitoneal route. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition, it emits acrid smoke and irritating fumes.
Hazard Codes:?Xi
Risk Statements: 36/37/38
R37/38:Irritating to respiratory system and skin.
Safety Statements: 22-24/25-36-26?
S22:Do not breathe dust.
S24/25:Avoid contact with skin and eyes.?
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36:Wear suitable protective clothing.
WGK Germany: 3
RTECS: GW4600000
F: 3-10
HS Code: 29181980?
?Shikimic acid , with a CAS number of?138-59-0, known as 3R,4S,5R)-(-)-3,4,5-Trihydroxy-1-cyclohexenecarboxylic acid ; and 3,4,5-Trihydroxy-1-cyclohexene-1-carboxylic acid . And its?classification code are mutation data, natural product,?tumor data.?Shikimic acid (CAS NO.138-59-0)?could be stable under normal temperatures and pressures. And it should avoid the condition like?strong oxidants.?And also prevent it to broken down into hazardous decomposition products:?carbon monoxide, irritating and toxic fumes and gases, carbon dioxide. Its hazardous polymerization has not been reported.
1. | ??? |
dlt-mus-ipr 1000?mg/kg |
??? | BJLSAF ?? Botanical Journal of the Linnean Society. 73 (1976),105. |
2. | ??? |
dlt-mus-orl 3200?mg/kg |
??? | NATUAS ?? Nature. 250 (1974),348. |
3. | ??? |
otr-ham:kdy 250?mg/L |
??? | TOLED5 ?? Toxicology Letters. 19 (1983),43. |
4. | ??? |
ipr-mus LD50:1000?mg/kg |
??? | NATUAS ?? Nature. 250 (1974),348. |
?Shikimic acid (CAS NO.138-59-0) has been listed as a carcinogen by IARC in Group 3. The toxicological properties have not been fully investigated. You can see actual entry in RTECS for complete information.
Not classified.
Pictogram(s) | No symbol. |
---|---|
Signal word | No signal word. |
Hazard statement(s) | none |
Precautionary statement(s) | |
Prevention | none |
Response | none |
Storage | none |
Disposal | none |
none
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