7-(difluoromethyl)-N-(4-isopropylphenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide

Iupac Name：(3R)-3-amino-1-[3-(trifluoromethyl)-6,8-dihydro-5H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)butan-1-one

Molecular Weight：407.31400

Modify Date.: 2022-04-12 13:48

1. Names and Identifiers

1.1 Name: 7-(difluoromethyl)-N-(4-isopropylphenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide

2. Properties

3. MSDS

Acute toxicity - Oral, Category 4

Serious eye damage, Category 1

Specific target organ toxicity \u2013 repeated exposure, Category 2

Pictogram(s)
Signal word	Danger
Hazard statement(s)	H302 Harmful if swallowed H318 Causes serious eye damage H373 May cause damage to organs through prolonged or repeated exposure
Precautionary statement(s)
Prevention	P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection. P260 Do not breathe dust/fume/gas/mist/vapours/spray.
Response	P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/\u2026if you feel unwell. P330 Rinse mouth. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P310 Immediately call a POISON CENTER/doctor/\u2026 P314 Get medical advice/attention if you feel unwell.
Storage	none
Disposal	P501 Dispose of contents/container to ...

none

4. Computational chemical data

Molecular Weight: 407.31400g/mol
Molecular Formula: C_₂₃H_₂₆N_₂O
Compound Is Canonicalized: True
XLogP3-AA: 0.7
Exact Mass: 407.11807909
Monoisotopic Mass: 407.11807909
Complexity: 566
Rotatable Bond Count: 4
Hydrogen Bond Donor Count: 1
Hydrogen Bond Acceptor Count: 10
Topological Polar Surface Area: 77
Heavy Atom Count: 28
Defined Atom Stereocenter Count: 1
Undefined Atom Stereocenter Count: 0
Defined Bond Stereocenter Count: 0
Undefined Bond Stereocenter Count: 0
Isotope Atom Count: 0
Covalently-Bonded Unit Count: 1
CACTVS Substructure Key Fingerprint: AAADccB7ocAAAAAAAAAAAAAAAAAAAWAAAAA8QAAAAAAAAFgBwAAAHwAYAAAADCjBmxwxEIdMEACqAiNyNAASgAsgAKAVyIEYAIiIaDqA2RGUIAAgngKIiAcYiICOAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA==

5. Question & Answer

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7. Realated Product Infomation

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445035-26-7 7-(Difluoromethyl)-N-(2,4-dimethylphenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide

445038-47-1 7-(difluoromethyl)-N-{4-[(mesitylamino)sulfonyl]phenyl}-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide

445036-85-1 7-(difluoromethyl)-N-(4-fluoro-2-methylphenyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide

445039-02-1 N-(2,6-dibromo-4-fluorophenyl)-7-(difluoromethyl)-5-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide

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