Troxerutin

2-[3,4-Bis(2-hydroxyethoxy)phenyl]-3-[[6-O-(6-deoxy-a-L-mannopyranosyl)-b-D-glucopyranosyl]oxy]-5-hydroxy-7-(2-hydroxyethoxy)-4H-1-benzopyran-4-one 2-[3,4-Bis(2-hydroxyethoxy)phenyl]-5-hydroxy-7-(2-hydroxyethoxy)-4-oxo-4H-chromen-3-yl 6-O-(6-deoxy-α-L-mannopyranosyl)-Β-D-glucopyranoside 4H-1-Benzopyran-4-one, 2-[3,4-bis(2-hydroxyethoxy)phenyl]-3-[[6-O-(6-deoxy-α-L-mannopyranosyl)-Β-D-glucopyranosyl]oxy]-5-hydroxy-7-(2-hydroxyethoxy)- 7,3',4'-trihydroxyethyl rutin 7,3',4'-Tris[O-(2-hydroxyethyl)]rutin EINECS 230-389-4 Factor-P-zyma MFCD00893813 Posorutin Rufen P-4 RUVEN T66 BO EVJ CR CO2Q DO2Q& GQ IO2Q DO- BT6OTJ CQ DQ EQ F1O-BT6OTJ CQ DQ EQ FQ &&Stereoisomer Tri(hydroxyethyl)rutoside Trioxyethylrutin troxerutina Troxerutine VASTRIBIL Venoruton P4 Venoruton P-4 Vitamin P4 Z-6000

Troxerutin , with the CAS register number 7085-55-4, is also known to us as ruven ; posorutin;troxerutin ; trihydroxyethylrutin ; vastribil;3',4',7-tris-o-(2-hydroxyethyl)rutin ; 2-[3,4-bis(2-hydroxyethoxy)phenyl]-3-[[6-o-(6-o-deoxy-a-l-mannopyranosyl)-beta-d-glucopyranosyl]oxy]-5-hydroxy-7-(2-hydroxyethoxy)-4h-1-benzopyran-4-one ; trihydroxylrutin .

The characteristics of this kind of chemical are as below: (1)#H bond acceptors:? 19? ; (2)#H bond donors:? 10? ; (3)#Freely Rotating Bonds:? 25? ; (4)Polar Surface Area:? 183.21 ; (5)Index of Refraction:? 1.689? ; (6)Molar Refractivity:? 171.18 cm³? ; (7)Molar Volume:? 447.9 cm³? ; (8)Polarizability:? 67.86 ×10-24cm^3? ; (9)Surface Tension:? 100.8 dyne/cm? ; (10)Density:? 1.65 g/cm^3? ; (11)Flash Point:? 332 °C? ; (12)Enthalpy of Vaporization:? 162.36 kJ/mol? ; (13)Boiling Point:? 1058.4 °C at 760 mmHg?.

This kind of chemical belong to the categories of miscellaneous natural products;natural plant extract;intermediates & fine chemicals;pharmaceuticals and so on. As for its usage, it is usually used as the anticoagulant which has the function of resisting the formation of thrombus and it is also applied in hemiplegic paralysis, myocardial infarction and arteriosclerosis caused by the cerebral thrombosis and cerebral embolism.

While using this kind of chemical, do not breathe dust and avoid contacting with skin and eyes. If yo need more safety information, you could refer to the WGK Germany? 3 .

In addition, you could obtain the molecular structure by converting the following data informaion:
SMILES:
O=C4c5c(O)cc(OCCO)cc5O/C(c1ccc(OCCO)c(OCCO)c1)=C4/O[C@@H]3O[C@H](CO[C@@H]2O[C@H]([C@H](O)[C@@H](O)[C@H]2O)C)[C@@H](O)[C@H](O)[C@H]3O
InChI:
InChI=1/C33H42O19/c1-14-23(38)26(41)28(43)32(49-14)48-13-21-24(39)27(42)29(44)33(51-21)52-31-25(40)22-17(37)11-16(45-7-4-34)12-20(22)50-30(31)15-2-3-18(46-8-5-35)19(10-15)47-9-6-36/h2-3,10-12,14,21,23-24,26-29,32-39,41-44H,4-9,13H2,1H3/t14-,21+,23-,24+,26+,27-,28+,29+,32+,33-/m0/s1

Toxicity Information of Troxerutin(7085-55-4):

CHEMICAL IDENTIFICATION

RTECS NUMBER :

LK8331500

CHEMICAL NAME :

Flavone, 3,5-dihydroxy-3',4',7-tris(2-hydroxyethoxy)-, 3-(6-O-(6-deoxy-alpha-L- mannopyranosyl)-beta-D-glucopyranoside)

CAS REGISTRY NUMBER :

7085-55-4

LAST UPDATED :

199612

DATA ITEMS CITED :

1

MOLECULAR FORMULA :

C33-H42-O19

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :

LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :

Intraperitoneal

SPECIES OBSERVED :

Rodent - rat

DOSE/DURATION :

27160 mg/kg

TOXIC EFFECTS :

Cardiac - arrhythmias (including changes in conduction) Cardiac - cardiomegaly Nutritional and Gross Metabolic - body temperature decrease

REFERENCE :

THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 20,879,1965