VAPREOTIDE
- Iupac Name：(4S,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-N-[(2S)-1-amino-3-(1H-indol-3-yl)-1-oxopropan-2-yl]-19-[[(2R)-2-amino-3-phenylpropanoyl]amino]-16-[(4-hydroxyphenyl)methyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-7-propan-2-yl-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide
- CAS No.: 103222-11-3
- Molecular Weight：1131.382
- Modify Date.: 2022-11-22 20:18
- Introduction: Vapreotide is a synthetic somatostatin (S676750) analog predominately used for the treatment of acute variceal bleeding. VAPREOTIDESupplier
View more+
1. Names and Identifiers
- 1.1 Name
- VAPREOTIDE
- 1.2 Synonyms
D-Phe-Cys-Trp-D-Trp-Lys-Val-Cys-Trp-CONH2(disulfide Cys2-Cys7) D-PHE-CYS-TYR-D-TRP-LYS-VAL-CYS-TRP-NH2 D-Phe-Cys-Tyr-D-Trp-Lys-Val-Cys-Trp-NH2 (Disulfide bridge Cys2-Cys7) FCYWKVCW-NH2 H-D-Phe-Cys-Tyr-D-Trp-Lys-Val-Cys-Trp-NH2 RC-160 VAPREOTIDE Vapreotide, RC-160
- 1.3 CAS No.
- 103222-11-3
- 1.4 CID
- 71306
- 1.5 Molecular Formula
- C57H70N12O9S2 (isomer)
- 1.6 Inchi
- InChI=1S/C57H70N12O9S2/c1-32(2)49-57(78)68-48(55(76)64-44(50(60)71)26-35-28-61-41-16-8-6-14-38(35)41)31-80-79-30-47(67-51(72)40(59)24-33-12-4-3-5-13-33)56(77)65-45(25-34-19-21-37(70)22-20-34)53(74)66-46(27-36-29-62-42-17-9-7-15-39(36)42)54(75)63-43(52(73)69-49)18-10-11-23-58/h3-9,12-17,19-22,28-29,32,40,43-49,61-62,70H,10-11,18,23-27,30-31,58-59H2,1-2H3,(H2,60,71)(H,63,75)(H,64,76)(H,65,77)(H,66,74)(H,67,72)(H,68,78)(H,69,73)
- 1.7 InChkey
- SWXOGPJRIDTIRL-UHFFFAOYSA-N
- 1.8 Canonical Smiles
- CC(C)C1C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=C(C=C4)O)NC(=O)C(CC5=CC=CC=C5)N)C(=O)NC(CC6=CNC7=CC=CC=C76)C(=O)N
- 1.9 Isomers Smiles
- CC(C)C1C(=O)NC(CSSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCCN)CC2=CNC3=CC=CC=C32)CC4=CC=C(C=C4)O)NC(=O)C(CC5=CC=CC=C5)N)C(=O)NC(CC6=CNC7=CC=CC=C76)C(=O)N
2. Properties
- 2.1 Density
- 1.4
- 2.1 Boiling point
- 1540.9 °C at 760 mmHg
- 2.1 Refractive index
- 1.699
- 2.1 Flash Point
- 885.7 °C
- 2.1 Precise Quality
- 1130.48000
- 2.1 PSA
- 401.24000
- 2.1 logP
- 6.53830
- 2.1 Storage
- ?20°C
- 2.2 pKa
- 9.90±0.15(Predicted)
- 2.3 StorageTemp
- −20°C
3. Use and Manufacturing
- 3.1 Usage
- Vapreotide is a synthetic somatostatin (S676750) analog predominately used for the treatment of acute variceal bleeding. VAPREOTIDESupplier
4. Safety and Handling
- 4.1 Safety Statements
- 22-24/25
- 4.1 Safety
-
Safety Statements: 22-24/25
S22: Do not breathe dust.
S24/25: Avoid contact with skin and eyes.
5. MSDS
2.Hazard identification
2.1 Classification of the substance or mixture
no data available
2.2 GHS label elements, including precautionary statements
| Pictogram(s) | no data available |
| Signal word | no data available |
| Hazard statement(s) | no data available |
| Precautionary statement(s) | |
| Prevention | no data available |
| Response | no data available |
| Storage | no data available |
| Disposal | no data available |
2.3 Other hazards which do not result in classification
no data available
7. Other Information
- 7.0 Uses
- Vapreotide is a synthetic somatostatin (S676750) analog predominately used for the treatment of acute variceal bleeding.
- 7.1 Mesh
- Compounds capable of relieving pain without the loss of CONSCIOUSNESS. (See all compounds classified as Analgesics.)|Substances that inhibit or prevent the proliferation of NEOPLASMS. (See all compounds classified as Antineoplastic Agents.)
- 7.2 Mesh Entry Terms
- D-Phe-Cys-Tyr-D-Trp-Lys-Val-Cys-Trp-NH2
8. Computational chemical data
- Molecular Weight: 1131.382g/mol
- Molecular Formula: C57H70N12O9S2
- Compound Is Canonicalized: True
- XLogP3-AA: 3.6
- Exact Mass: 1130.48301420
- Monoisotopic Mass: 1130.48301420
- Complexity: 2080
- Rotatable Bond Count: 18
- Hydrogen Bond Donor Count: 13
- Hydrogen Bond Acceptor Count: 13
- Topological Polar Surface Area: 401
- Heavy Atom Count: 80
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count: 8
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Isotope Atom Count: 0
- Covalently-Bonded Unit Count: 1
- CACTVS Substructure Key Fingerprint: AAADcfB//ABgAAAAAAAAAAAAAAAAAWLAAAAwYMGAAAAAAFgB/gAAHgQQCAAADSzF3gS+xvLJkgCoAzV3VACCgCAxIiAI2aG+bJgIZvLCkbOUcAhk1hHI2AeYyeCOoAAAAAACAABAAAAAAAQAAAAAAAAAAA==
9. Recommended Suppliers
-
- Products:API,fine chemical&its intermediates,biological chemistry
- Tel:0086-27-59207850
- Email:info@fortunachem.com
-
- Products:Our company is an internationally oriented research based pharmaceutical company with headquarters located in Hangzhou,China.
- Tel:86-571-87758665
- Email:joyce@utanpharma.com
Vapreotide
- Purity:99%Packing: 200kg/bag FOB
- Price: 0 USD/kilogram
- Time: 2023/01/17
Inquire
-
- Products:Veterinary products,Nutrition products,Agrochemicals,Active pharmaceutical Ingredients,Custom systhesis,Contract manufacturing
- Tel:86-571-85829052
- Email:market@royalpharms.com
-
- Products:Anabolic Steroid Hormone Powder, Muscle Building Steroids, Oral Anabolic Steroids, Injectable Anabolic Steroids, Pharmaceutical Raw Materials, Food Additives, Flavor&,Fragrance
- Tel:86-27-68886732
-
- Products:API,intermediate, Agrochemical,Amino Acids
- Tel:86-27-59009407
VAPREOTIDE
- Purity:99%Packing: 200kg/bag FOB
- Price: 10 USD/kilogram
- Time: 2020/06/28
Inquire
10. Realated Product Infomation
skype
10YRS
