![]() |
![]() |
2H-1-Benzopyran-2-one, 4-hydroxy-3-(3-oxo-1-phenylbutyl)-, sodium salt (1:1) 3-(A-ACETONYLBENZYL)-4-HYDROXYCOUMARIN 3-(A-ACETONYLBENZYL)-4-HYDROXYCOUMARIN SODIUM 3-(A-ACETONYLBENZYL)-4-HYDROXYCOUMARIN SODIUM SALT 3-(ALPHA-ACETONYLBENZYL)-4-HYDROXYCOUMARIN 3-(Alpha-Acetonylbenzyl)-4-Hydroxycoumarin Sodiuim Salt 3-(ALPHA-ACETONYLBENZYL)-4-HYDROXYCOUMARIN SODIUM 3-(ALPHA-ACETONYLBENZYL)-4-HYDROXYCOUMARIN SODIUM CLATHRATE 3-(α-Acetonylbenzyl)-4-hydroxycoumarin Sodiuim Salt (contains Isopropyl Alcohol) 3-(α-ACETONYLBENZYL)-4-HYDROXYCOUMARIN SODIUM SALT 4-hydroxy-3-(3-oxo-1-phenylbutyl)-2H-1-benzopyran-2-one sodium salt 4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin Sodium Salt (contains Isopropyl Alcohol) coumadin EINECS 204-929-4 marevan MFCD00083223 panwarfin rac-sodium 2-oxo-3-[(1R)-3-oxo-1-phenylbutyl]-2H-1-benzopyran-4-olate Sodium 2-oxo-3-(3-oxo-1-phenylbutyl)-2H-chromen-4-olate sodium 2-oxo-3-[(RS)-3-oxo-1-phenylbutyl]-2H-chromen-4-olate sodiumcoumadin sodiumwarfarin UNII:6153CWM0CL waran Warfarin SodiuM (contains Isopropyl Alcohol) warfarin sodium salt WARFARIN SODIUM, (CONTAINS ISOPROPYL ALCOHOL) WARFARIN SODIUM, EP STANDARD WARFARIN SODIUMLINE Warfarinsodium zoocoumarin-sodium
Reported in EPA TSCA Inventory. EPA Extremely Hazardous Substances List.
Safety Information of?Warfarin sodium (CAS NO.129-06-6):
Hazard Codes:T+
Risk Statements:61-28
Safety Statements:53-36/37/39-45
RIDADR:UN 1544 6.1/PG 2
WGK Germany:1
RTECS:GN4725000
HazardClass:6.1(a)
PackingGroup:II
Poison to humans by ingestion. Experimental poison by ingestion and intravenous routes. Human systemic effects by ingestion: dermatitis. Human reproductive effects by ingestion: fetotoxicity, abnormal condition of newborn at birth, other newborn physical effects, and teratogenic effects including developmental abnormalities of the eye and ear, craniofacial area, skin and appendages, musculoskeletal system, cardiovascular system, and gastrointestinal system of the fetus. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. An anticoagulant drug. When heated to decomposition it emits toxic fumes of Na2O.
First Aid Measures of?Warfarin sodium (CAS NO.129-06-6):
Ingestion:Give water and induce vomiting. Never give anthing to an unconscious person. Obtain medical attention.
Inhalation:Remove to fresh air. Give CPR and/or oxygen if required.
Skin:Wash with soap and water.
Eyes:Flush with water for 15 minutes.
Storage of Warfarin sodium (CAS NO.129-06-6):
Store at away from heat and open flame. Do not store near feeds and foodstuffs and keep away from children, domestic animals, pets, or wildlife.
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
chicken | LD50 | intravenous | 200mg/kg (200mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BLOOD: HEMORRHAGE SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 379, 1953. |
child | TDLo | oral | 4mg/kg (4mg/kg) | BLOOD: CHANGES IN CELL COUNT (UNSPECIFIED) | American Journal of Diseases of Children. Vol. 147, Pg. 609, 1993. |
dog | LD50 | intravenous | 200mg/kg (200mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BLOOD: HEMORRHAGE SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 379, 1953. |
dog | LD50 | oral | 200mg/kg (200mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 379, 1953. |
guinea pig | LD50 | oral | 182mg/kg (182mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 379, 1953. |
guinea pig | LDLo | intravenous | 543mg/kg (543mg/kg) | ? | Therapie. Vol. 18, Pg. 921, 1963. |
mouse | LD50 | intravenous | 160mg/kg (160mg/kg) | ? | "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 123, 1969. |
mouse | LD50 | oral | 374mg/kg (374mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 379, 1953. |
rabbit | LD50 | intravenous | 100mg/kg (100mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BLOOD: HEMORRHAGE SKIN AND APPENDAGES (SKIN): HAIR: OTHER |
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 379, 1953. |
rabbit | LD50 | oral | 800mg/kg (800mg/kg) | BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD |
Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 42, Pg. 379, 1953. |
rat | LD50 | intravenous | 25mg/kg (25mg/kg) | ? | "Handbook of Analytical Toxicology," Sunshine, I., ed., Cleveland, OH, Chemical Rubber Co., 1969Vol. -, Pg. 123, 1969. |
rat | LD50 | oral | 8700ug/kg (8.7mg/kg) | BLOOD: HEMORRHAGE | Pharmacological Research Communications. Vol. 10, Pg. 445, 1978. |
women | TDLo | oral | 300ug/kg/2D (0.3mg/kg) | SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" | Archives of Dermatology. Vol. 116, Pg. 444, 1980. |
Acute toxicity - Oral, Category 2
Acute toxicity - Dermal, Category 1
Acute toxicity - Inhalation, Category 2
Reproductive toxicity, Category 1A
Specific target organ toxicity \u2013 repeated exposure, Category 1
Pictogram(s) | ![]() ![]() |
---|---|
Signal word | Danger |
Hazard statement(s) | H300 Fatal if swallowed H310 Fatal in contact with skin H330 Fatal if inhaled H372 Causes damage to organs through prolonged or repeated exposure |
Precautionary statement(s) | |
Prevention | P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P262 Do not get in eyes, on skin, or on clothing. P280 Wear protective gloves/protective clothing/eye protection/face protection. P260 Do not breathe dust/fume/gas/mist/vapours/spray. P271 Use only outdoors or in a well-ventilated area. P284 [In case of inadequate ventilation] wear respiratory protection. P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. |
Response | P301+P310 IF SWALLOWED: Immediately call a POISON CENTER/doctor/\u2026 P321 Specific treatment (see ... on this label). P330 Rinse mouth. P302+P352 IF ON SKIN: Wash with plenty of water/... P310 Immediately call a POISON CENTER/doctor/\u2026 P361+P364 Take off immediately all contaminated clothing and wash it before reuse. P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing. P320 Specific treatment is urgent (see ... on this label). P308+P313 IF exposed or concerned: Get medical advice/ attention. P314 Get medical advice/attention if you feel unwell. |
Storage | P405 Store locked up. P403+P233 Store in a well-ventilated place. Keep container tightly closed. |
Disposal | P501 Dispose of contents/container to ... |
none
![]() |