Yellow pyoctanine
- Iupac Name：4-[4-(dimethylamino)benzenecarboximidoyl]-N,N-dimethylaniline
- CAS No.: 492-80-8
- Molecular Weight：267.376
- Modify Date.: 2022-11-07 06:29
- Introduction: Yellow dye for paper, textiles, leather; antisep-tic; fungicide.
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1. Names and Identifiers
- 1.1 Name
- Yellow pyoctanine
- 1.2 Synonyms
4,4'-bis(N,N-dimethylamino)benzophenone 4,4'-bis-dimethylamino-benzophenone-imine 4,4'-Bis-dimethylamino-benzophenon-imin 4,4'-carbonimidoylbis[N,N-dimethylaniline] 4,4'-Dimethylaminobenzophenonimide Apyonin Auramine Base Auramine N Base Auramine OAF Auramine SS Baso Yellow 124 Blauramine C.I. 41000B C.I. Basic Yellow 2, Free Base C.I. Solvent Yellow 34 Carbonoimidoylbis(N,N-dimethylbenzenamine) CISOLVENTYELLOW EINECS 207-762-5 Waxoline yellow D
- 1.3 CAS No.
- 492-80-8
- 1.4 CID
- 10298
- 1.5 EINECS(EC#)
- 207-762-5
- 1.6 Molecular Formula
- C17H21N3 (isomer)
- 1.7 Inchi
- InChI=1S/C17H21N3/c1-19(2)15-9-5-13(6-10-15)17(18)14-7-11-16(12-8-14)20(3)4/h5-12,18H,1-4H3
- 1.8 InChkey
- JPIYZTWMUGTEHX-UHFFFAOYSA-N
- 1.9 Canonical Smiles
- CN(C)C1=CC=C(C=C1)C(=N)C2=CC=C(C=C2)N(C)C
- 1.10 Isomers Smiles
- CN(C)C1=CC=C(C=C1)C(=N)C2=CC=C(C=C2)N(C)C
2. Properties
- 2.1 Density
- 1.01
- 2.1 Melting point
- 136 DEG C
- 2.1 Boiling point
- 406.2 °C at 760 mmHg
- 2.1 Refractive index
- 1.555
- 2.1 Flash Point
- 199.4 °C
- 2.2 Precise Quality
- 267.17400
- 2.2 PSA
- 30.33000
- 2.2 logP
- 3.33450
- 2.2 VaporDensity
- 4.38 (vs air)
- 2.3 AnalyticLaboratory Methods
- AURAMINE; WAS SEPARATED BY TWO-DIMENSIONAL PAPER CHROMATOGRAPHY.
- 2.4 Appearance
- yellow powder
- 2.5 Chemical Properties
- Auramine is a yellow crystalline powder orflaky material.
- 2.6 Color/Form
- YELLOW OR COLORLESS PLATES FROM ALCOHOL
- 2.7 Decomposition
- DECOMPOSES @ TEMP ABOVE 70 DEG C.
- 2.8 PH
- IS WEAK BASE THAT FORMS SALTS WITH HYDROCHLORIC ACID;, SULFURIC ACID;.
- 2.9 Physical
- C.I. SOLVENT YELLOW 34; is a yellow crystalline powder or yellow needles.
- 2.10 pKa
- 10.12±0.50(Predicted)
- 2.11 Water Solubility
- 27.9 g/L (20 o C)
- 2.12 Spectral Properties
- MAX ABSORPTION (ACETIC ACID): 270 NM (LOG E= 3.48); 372 NM (LOG E= 3.54); 440 NM (LOG E= 3.74)
3. Use and Manufacturing
- 3.1 Agricultural Uses
- Fungicide: Auramine is used industrially as a dye or dye intermediate for coloring textiles, paper, and leather. Alsoused as an antiseptic (a powerful antiseptic in ear and nosesurgery and in gonorrhea treatment)
- 3.2 Definition
- ChEBI: A member of the class of imines that is benzophenone imine carrying two dimethylamino substituents at positions 4 and 4'. The hydrochloride salt is the biological stain 'auramine O'
- 3.3 General Description
- Yellow crystalline powder or yellow needles.
- 3.4 GHS Classification
- Signal: Warning
GHS Hazard Statements
H302: Harmful if swallowed [Warning Acute toxicity, oral]
H319: Causes serious eye irritation [Warning Serious eye damage/eye irritation]
H351: Suspected of causing cancer [Warning Carcinogenicity]
H411: Toxic to aquatic life with long lasting effects [Hazardous to the aquatic environment, long-term hazard]
Precautionary Statement Codes
P201, P202, P264, P270, P273, P280, P281, P301+P312, P305+P351+P338, P308+P313, P330, P337+P313, P391, P405, and P501
- 3.5 Methods of Manufacturing
- REACTION OF DIMETHYLANILINE; WITH FORMALDEHYDE; FORMING MICHLER'S BASE;, FOLLOWED BY HEATING WITH SULFUR; AND AMMONIUM CHLORIDE; IN THE PRESENCE OF AMMONIA;.
- 3.6 Potential Exposure
- Auramine is used industrially as a dyeor dye intermediate for coloring textiles; paper, and leather.Also used as an antiseptic (a powerful antiseptic in ear andnose surgery, and treatment of gonorrhea) and fungicide.Human exposure to auramine occurs principally throughskin absorption or inhalation of vapors. Low-level dermalexposure to the consumer may occur but would be limitedto any migration of auramine from fabric, leather, or papergoods.
- 3.7 Shipping
- UN2811 Toxic solids, organic, n.o.s., HazardClass: 6.1; Labels: 6.1-Poisonous materials, TechnicalName Required. UN3143 Dyes, solid, toxic, n.o.s. or Dyeintermediates, solid, toxic, n.o.s., Hazard Class: 6.1;Labels: 6.1-Poisonous materials, Technical Name Required.
- 3.8 Usage
- Yellow dye for paper, textiles, leather; antisep-tic; fungicide.
4. Safety and Handling
- 4.1 Symbol
- GHS07, GHS08, GHS09
- 4.1 Hazard Codes
- N,Xn
- 4.1 Signal Word
- Warning
- 4.1 Risk Statements
- R22
- 4.1 Safety Statements
- Confirmed human carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by intraperitoneal route. Human mutation data reported. Used as an antiseptic. When heated to decomposition it emits toxic fumes of NOx.
- 4.1 Fire Hazard
- Some may burn but none ignite readily. Containers may explode when heated. Some may be transported hot.
- 4.2 Other Preventative Measures
- PRECAUTIONS FOR "CARCINOGENS": Smoking, drinking, eating, storage of food or of food & beverage containers or utensils, & the application of cosmetics should be prohibited in any laboratory. All personnel should remove gloves, if worn, after completion of procedures in which carcinogens have been used. They should ... wash ... hands, preferably using dispensers of liq detergent, & rinse ... thoroughly. Consideration should be given to appropriate methods for cleaning the skin, depending on nature of the contaminant. No standard procedure can be recommended, but the use of organic solvents should be avoided. Safety pipettes should be used for all pipetting. /Chemical Carcinogens/
PRECAUTIONS FOR "CARCINOGENS": In animal laboratory, personnel should remove their outdoor clothes & wear protective suits (preferably disposable, one-piece & close-fitting at ankles & wrists), gloves, hair covering & overshoes. ... clothing should be changed daily but ... discarded immediately if obvious contamination occurs ... /also,/ workers should shower immediately. In chemical laboratory, gloves & gowns should always be worn ... however, gloves should not be assumed to provide full protection. Carefully fitted masks or respirators may be necessary when working with particulates or gases, & disposable plastic aprons might provide addnl protection. If gowns are of distinctive color, this is a reminder that they should not be worn outside of lab. /Chemical Carcinogens/
PRECAUTIONS FOR "CARCINOGENS": ... Operations connected with synth & purification ... should be carried out under well-ventilated hood. Analytical procedures ... should be carried out with care & vapors evolved during ... procedures should be removed. ... Expert advice should be obtained before existing fume cupboards are used ... & when new fume cupboards are installed. It is desirable that there be means for decreasing the rate of air extraction, so that carcinogenic powders can be handled without ... powder being blown around the hood. Glove boxes should be kept under negative air pressure. Air changes should be adequate, so that concn of vapors of volatile carcinogens will not occur. /Chemical Carcinogens/
PRECAUTIONS FOR "CARCINOGENS": Vertical laminar-flow biological safety cabinets may be used for containment of in vitro procedures ... provided that the exhaust air flow is sufficient to provide an inward air flow at the face opening of the cabinet, & contaminated air plenums that are under positive pressure are leak-tight. Horizontal laminar-flow hoods or safety cabinets, where filtered air is blown across the working area towards the operator, should never be used ... Each cabinet or fume cupboard to be used ... should be tested before work is begun (eg, with fume bomb) & label fixed to it, giving date of test & avg air-flow measured. This test should be repeated periodically & after any structural changes. /Chemical Carcinogens/
PRECAUTIONS FOR "CARCINOGENS": Principles that apply to chem or biochem lab also apply to microbiological & cell-culture labs ... Special consideration should be given to route of admin. ... Safest method of administering volatile carcinogen is by injection of a soln. Admin by topical application, gavage, or intratracheal instillation should be performed under hood. If chem will be exhaled, animals should be kept under hood during this period. Inhalation exposure requires special equipment. ... unless specifically required, routes of admin other than in the diet should be used. Mixing of carcinogen in diet should be carried out in sealed mixers under fume hood, from which the exhaust is fitted with an efficient particulate filter. Techniques for cleaning mixer & hood should be devised before expt begun. When mixing diets, special protective clothing &, possibly, respirators may be required. /Chemical Carcinogens/
PRECAUTIONS FOR "CARCINOGENS": When ... admin in diet or applied to skin, animals should be kept in cages with solid bottoms & sides & fitted with a filter top. When volatile carcinogens are given, filter tops should not be used. Cages which have been used to house animals that received carcinogens should be decontaminated. Cage-cleaning facilities should be installed in area in which carcinogens are being used, to avoid moving of ... contaminated /cages/. It is difficult to ensure that cages are decontaminated, & monitoring methods are necessary. Situations may exist in which the use of disposable cages should be recommended, depending on type & amt of carcinogen & efficiency with which it can be removed. /Chemical Carcinogens/
PRECAUTIONS FOR "CARCINOGENS": To eliminate risk that ... contamination in lab could build up during conduct of expt, periodic checks should be carried out on lab atmospheres, surfaces, such as walls, floors & benches, & ... interior of fume hoods & airducts. As well as regular monitoring, check must be carried out after cleaning-up of spillage. Sensitive methods are required when testing lab atmospheres. ... Methods ... should ... where possible, be simple & sensitive. /Chemical Carcinogens/
PRECAUTIONS FOR "CARCINOGENS": Rooms in which obvious contamination has occurred, such as spillage, should be decontaminated by lab personnel engaged in expt. Design of expt should ... avoid contamination of permanent equipment. ... Procedures should ensure that maintenance workers are not exposed to carcinogens. ... Particular care should be taken to avoid contamination of drains or ventilation ducts. In cleaning labs, procedures should be used which do not produce aerosols or dispersal of dust, ie, wet mop or vacuum cleaner equipped with high-efficiency particulate filter on exhaust, which are avail commercially, should be used. Sweeping, brushing & use of dry dusters or mops should be prohibited. Grossly contaminated cleaning materials should not be re-used ... If gowns or towels are contaminated, they should not be sent to laundry, but ... decontaminated or burnt, to avoid any hazard to laundry personnel. /Chemical Carcinogens/
PRECAUTIONS FOR "CARCINOGENS": Doors leading into areas where carcinogens are used ... should be marked distinctively with appropriate labels. Access ... limited to persons involved in expt. ... A prominently displayed notice should give the name of the Scientific Investigator or other person who can advise in an emergency & who can inform others (such as firemen) on the handling of carcinogenic substances. /Chemical Carcinogens/
SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.
- 4.3 Hazard Declaration
- H302-H319-H351-H411
- 4.3 Cleanup Methods
- PRECAUTIONS FOR "CARCINOGENS": A high-efficiency particulate arrestor (HEPA) or charcoal filters can be used to minimize amt of carcinogen in exhausted air ventilated safety cabinets, lab hoods, glove boxes or animal rooms ... Filter housing that is designed so that used filters can be transferred into plastic bag without contaminating maintenance staff is avail commercially. Filters should be placed in plastic bags immediately after removal ... The plastic bag should be sealed immediately ... The sealed bag should be labelled properly ... Waste liquids ... should be placed or collected in proper containers for disposal. The lid should be secured & the bottles properly labelled. Once filled, bottles should be placed in plastic bag, so that outer surface ... is not contaminated ... The plastic bag should also be sealed & labelled. ... Broken glassware ... should be decontaminated by solvent extraction, by chemical destruction, or in specially designed incinerators. /Chemical Carcinogens/
- 4.4 DisposalMethods
- Generators of waste (equal to or greater than 100 kg/mo) containing this contaminant, EPA hazardous waste number U014, must conform with USEPA regulations in storage, transportation, treatment and disposal of waste.
A potential candidate for rotary kiln incineration at a temperature range of 820 to 1,600 deg C and residence times of seconds for liquids and gases, and hours for solids. A potential candidate for fluidized bed incineration at a temperature range of 450 to 980 deg C and residence times of seconds for liquids and gases, and longer for solids.
PRECAUTIONS FOR "CARCINOGENS": There is no universal method of disposal that has been proved satisfactory for all carcinogenic compounds & specific methods of chem destruction ... published have not been tested on all kinds of carcinogen-containing waste. ... summary of avail methods & recommendations ... /given/ must be treated as guide only. /Chemical Carcinogens/
PRECAUTIONS FOR "CARCINOGENS": ... Incineration may be only feasible method for disposal of contaminated laboratory waste from biological expt. However, not all incinerators are suitable for this purpose. The most efficient type ... is probably the gas-fired type, in which a first-stage combustion with a less than stoichiometric air:fuel ratio is followed by a second stage with excess air. Some ... are designed to accept ... aqueous & organic-solvent solutions, otherwise it is necessary ... to absorb soln onto suitable combustible material, such as sawdust. Alternatively, chem destruction may be used, esp when small quantities ... are to be destroyed in laboratory. /Chemical Carcinogens/
PRECAUTIONS FOR "CARCINOGENS": HEPA (high-efficiency particulate arrestor) filters ... can be disposed of by incineration. For spent charcoal filters, the adsorbed material can be stripped off at high temp & carcinogenic wastes generated by this treatment conducted to & burned in an incinerator. ... LIQUID WASTE: ... Disposal should be carried out by incineration at temp that ... ensure complete combustion. SOLID WASTE: Carcasses of lab animals, cage litter & misc solid wastes ... should be disposed of by incineration at temp high enough to ensure destruction of chem carcinogens or their metabolites. /Chemical Carcinogens/
PRECAUTIONS FOR "CARCINOGENS": ... Small quantities of ... some carcinogens can be destroyed using chem reactions ... but no general rules can be given. ... As a general technique ... treatment with sodium dichromate in strong sulfuric acid can be used. The time necessary for destruction ... is seldom known ... but 1-2 days is generally considered sufficient when freshly prepd reagent is used. ... Carcinogens that are easily oxidizable can be destroyed with milder oxidative agents, such as saturated soln of potassium permanganate in acetone, which appears to be a suitable agent for destruction of hydrazines or of compounds containing isolated carbon-carbon double bonds. Concn or 50% aqueous sodium hypochlorite can also be used as an oxidizing agent. /Chemical Carcinogens/
PRECAUTIONS FOR "CARCINOGENS": Carcinogens that are alkylating, arylating or acylating agents per se can be destroyed by reaction with appropriate nucleophiles, such as water, hydroxyl ions, ammonia, thiols & thiosulfate. The reactivity of various alkylating agents varies greatly ... & is also influenced by sol of agent in the reaction medium. To facilitate the complete reaction, it is suggested that the agents be dissolved in ethanol or similar solvents. ... No method should be applied ... until it has been thoroughly tested for its effectiveness & safety on material to be inactivated. For example, in case of destruction of alkylating agents, it is possible to detect residual compounds by reaction with 4(4-nitrobenzyl)-pyridine. /Chemical Carcinogens/
- 4.5 RIDADR
- UN 3077 9 / PGIII
- 4.5 Caution Statement
- P273-P281-P305 + P351 + P338
- 4.5 Incompatibilities
- Incompatible with oxidizers (chlorates,nitrates, peroxides, permanganates, perchlorates, chlorine,bromine, fluorine, etc.); contact may cause fires or explosions.Keep away from alkaline materials, strong bases,strong acids, oxoacids, epoxides.
- 4.6 WGK Germany
- 3
- 4.6 RTECS
- BY3500000
- 4.6 Protective Equipment and Clothing
- INJURIOUS TO ... HUMAN EYES.
- 4.7 Report
-
IARC Cancer Review: Group 2B IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 , 1987,p. 118.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 1 , 1972,p. 69.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Sufficient Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 1 , 1972,p. 69.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . Community Right-To-Know List. Reported in EPA TSCA Inventory.
- 4.8 Skin, Eye, and Respiratory Irritations
- INJURIOUS TO ... HUMAN EYES.
- 4.9 Safety
-
Safety Information of Auramine (492-80-8):
Hazard Codes: Xn .gif)
,N .gif)
Risk Statements: 22-36-40-51/53
23: Toxic by inhalation
36: Irritating to the eyes
40: Limited evidence of a carcinogenic effect
51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Safety Statements: 36/37-61
36/37: Wear suitable protective clothing and gloves
61: Avoid release to the environment. Refer to special instructions safety data sheet
Confirmed human carcinogen with experimental carcinogenic, neoplastigenic, and tumorigenic data. Poison by intraperitoneal route. Human mutation data reported. Used as an antiseptic. When heated to decomposition it emits toxic fumes of NOx.
- 4.10 Specification
-
Auramine (492-80-8) is yellow crystalline powder or yellow needles, known as 4,4'-(Imidocarbonyl)bis(N,N-dimethylaniline) ; 4,4'-Carbonimidoylbis(N,N-dimethylbenzenamine) ; 4,4'-Dimethylaminobenzophenonimide ; 4-14-00-00256 (Beilstein Handbook Reference) ; AI3-17282 ; Aniline, 4,4'-imidocarbonylbis(N,N-dimethyl- ; Apyonine auramine base ; Auramine (free base) ; Auramine N base ; Auramine O base ; Auramine OAF ; Auramine OO ; Auramine SS ; Auramine base ; Bis(p-dimethylaminophenyl)methyleneimine ; Brilliant Oil Yellow ; C.I. 41000B ; C.I. Solvent Yellow 34 ; CCRIS 58 ; CI 41000B ; CI Basic Yellow 2, free base ; CI Solvent Yellow 34 ; Caswell No. 063A ; EPA Pesticide Chemical Code 039501 ; Glauramine ; HSDB 2935 ; Orient Oil Yellow 101 ; RCRA waste number U014 ; Tetramethyl-p-diamino-imido-benzophenone ; Waxoline Yellow O ; Yellow pyoctanine ; 4,4'-Carbonimidoylbis(N,N-dimethylaniline) ; Aniline, 4,4'-(imidocarbonyl)bis(N,N-dimethyl- ; Benzenamine, 4,4'-carbonimidoylbis(N,N-dimethyl- .
- 4.11 Toxicity
-
| 1. |
|
mma-sat 250 µg/plate
|
|
PMRSDJ Progress in Mutation Research. 1 (1981),333. |
| 2. |
|
dns-hmn:fbr 20 mg/L
|
|
TXCYAC Toxicology. 21 (1981),151. |
| 3. |
|
otr-rat-orl 150 mg/kg
|
|
CNREA8 Cancer Research. 40 (1980),1157. |
| 4. |
|
otr-ham:kdy 13,100 µg/L
|
|
PMRSDJ Progress in Mutation Research. 1 (1981),626. |
| 5. |
|
otr-ham:emb 2 mg/L
|
|
NCIMAV National Cancer Institute, Monograph. 58 (1981),243. |
| 6. |
|
ipr-mus LD50:103 mg/kg
|
|
PMRSDJ Progress in Mutation Research. 1 (1981),682. |
5. MSDS
2.Hazard identification
2.1 Classification of the substance or mixture
Acute toxicity - Oral, Category 4
Eye irritation, Category 2
Carcinogenicity, Category 2
Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2
2.2 GHS label elements, including precautionary statements
| Pictogram(s) |    |
| Signal word | Warning |
| Hazard statement(s) | H302 Harmful if swallowed H319 Causes serious eye irritation H351 Suspected of causing cancer H411 Toxic to aquatic life with long lasting effects |
| Precautionary statement(s) | |
| Prevention | P264 Wash ... thoroughly after handling. P270 Do not eat, drink or smoke when using this product. P280 Wear protective gloves/protective clothing/eye protection/face protection. P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P273 Avoid release to the environment. |
| Response | P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/…if you feel unwell. P330 Rinse mouth. P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313 If eye irritation persists: Get medical advice/attention. P308+P313 IF exposed or concerned: Get medical advice/ attention. P391 Collect spillage. |
| Storage | P405 Store locked up. |
| Disposal | P501 Dispose of contents/container to ... |
2.3 Other hazards which do not result in classification
none
6. Synthesis Route
492-80-8Total: 20 Synthesis Route
8. Other Information
- 8.0 BRN
- 2215338
- 8.1 Chemical Properties
- Auramine is a yellow crystalline powder or flaky material.
- 8.2 Uses
- Yellow dye for paper, textiles, leather; antisep- tic; fungicide.
- 8.3 Preparation
- (a) will Sulphur dissolved in 4-(4-(Dimethylamino)benzyl)-N,N-dimethylbenzenamine?methane. Add in ammonia and sodium chloride, ammonia in 175 ℃ heat the mixture, with hot water extraction dye and salting out (GP53614); (b) Bis (4 – (dimethylamino) phenyl) methanone and ammonia and Zinc chloride in a total of 150 ~ 160 ℃ heat (GP 29060). Free base is to add the same amount of naoh aqueous solution hydrochloride, sodium carbonate and ammonia and have to.
- 8.4 Definition
- ChEBI: A member of the class of imines that is benzophenone imine carrying two dimethylamino substituents at positions 4 and 4'. The hydrochloride salt is the biological stain 'auramine O'
- 8.5 General Description
- Yellow crystalline powder or yellow needles.
- 8.6 Reactivity Profile
- Yellow pyoctanine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. May generate hydrogen, a flammable gas, in combination with strong reducing agents such as hydrides.
- 8.7 Hazard
- Confirmed carcinogen.
- 8.8 Health Hazard
- Inhalation of material may be harmful. Contact may cause burns to skin and eyes. Inhalation of Asbestos dust may have a damaging effect on the lungs. Fire may produce irritating, corrosive and/or toxic gases. Some liquids produce vapors that may cause dizziness or suffocation. Runoff from fire control may cause pollution.
- 8.9 Fire Hazard
- Some may burn but none ignite readily. Containers may explode when heated. Some may be transported hot.
- 8.10 Agricultural Uses
- Fungicide: Auramine is used industrially as a dye or dye intermediate for coloring textiles, paper, and leather. Also used as an antiseptic (a powerful antiseptic in ear and nose surgery and in gonorrhea treatment)
- 8.11 Trade name
- WAXOLINE YELLOW O?
- 8.12 Potential Exposure
- Auramine is used industrially as a dye or dye intermediate for coloring textiles; paper, and leather. Also used as an antiseptic (a powerful antiseptic in ear and nose surgery, and treatment of gonorrhea) and fungicide. Human exposure to auramine occurs principally through skin absorption or inhalation of vapors. Low-level dermal exposure to the consumer may occur but would be limited to any migration of auramine from fabric, leather, or paper goods.
- 8.13 Shipping
- UN2811 Toxic solids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required. UN3143 Dyes, solid, toxic, n.o.s. or Dye intermediates, solid, toxic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.
- 8.14 Melting point
- Stable
- 8.15 Incompatibilities
- Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides.
- 8.16 Waste Disposal
- Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform with EPA regulations governing storage, transportation, treatment, and waste disposal. Incinerate in furnace with afterburner and scrubber.
9. Computational chemical data
- Molecular Weight: 267.376g/mol
- Molecular Formula: C17H21N3
- Compound Is Canonicalized: True
- XLogP3-AA: null
- Exact Mass: 267.173547683
- Monoisotopic Mass: 267.173547683
- Complexity: 278
- Rotatable Bond Count: 4
- Hydrogen Bond Donor Count: 1
- Hydrogen Bond Acceptor Count: 3
- Topological Polar Surface Area: 30.3
- Heavy Atom Count: 20
- Defined Atom Stereocenter Count: 0
- Undefined Atom Stereocenter Count: 0
- Defined Bond Stereocenter Count: 0
- Undefined Bond Stereocenter Count: 0
- Isotope Atom Count: 0
- Covalently-Bonded Unit Count: 1
- CACTVS Substructure Key Fingerprint: AAADceB7AAAAAAAAAAAAAAAAAAAAAAAAAAAwYAAAAAAAAAABQAAAHAAQAAAADAiBGAQywINAAACgAyRiQACCAAAhAgAIiAAoZJgIIKLAkZGEIAhggABIyAcQgMAOCAAAAAAAAAAQAAAAAAAAAAAAAAAAAA==
10. Recommended Suppliers
-
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- Tel:+86-311-89278944
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11. Realated Product Infomation
![70600;Anthraquinone Yellow;Flavanthrene;Flavanthrone (8CI);Flavanthrone Yellow;Indanthren Yellow GLP;Indanthrene Yellow G;Permanent Indian Yellow (hue) [LQd];Pigment Yellow 24*;Pigment Yellow 112;Vat Yellow 1](https://structimg.guidechem.com/5/17/612076.png)
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