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Immune Function Agents

Immunosuppressants are drugs that can inhibit the immune response of the body, inhibit the proliferation and function of cells related to immune response, and reduce the immune response of antibodies. It is mainly used in autoimmune diseases and organ transplantation anti-rejection. Common immunosuppressants include glucocorticoids, microbial metabolites, anti-metabolites, polyclonal and monoclonal anti-lymphocyte antibodies and alkylating agents, according to synthesis methods, can be divided into microbial glycolysis products, complete organic synthesis, semisynthetic compounds, biological agents and so on.

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Pelubiprofen; 69956-77-0 structural formula
Pelubiprofen
  • CAS No: 69956-77-0
  • Molecular Weight: 258.317
  • Molecular Formula:C16H18O3
  • Density:1.199
  • Boiling Point:457.4°C at 760 mmHg
  • Flash Point:244.5°C
Encyclopedia Safety and Handling MSDS 5 Suppliers Request For Quotation
Pimecrolimus; 137071-32-0 structural formula
Pimecrolimus
  • Pimecrolimus is an immunophilin ligand, which binds specifically to the cytosolic receptor, immunophilin macrophilin-12.Target: OthersPimecrolimus blocks T-lymphocyte activation pathway by inhibiting calcineurin function [1]. Pimecrolimus prevents the release of cytokines and pro-inflammatory mediat..
  • CAS No: 137071-32-0
  • Molecular Weight: 810.463
  • Molecular Formula:C43H68ClNO11
  • Density:1.19
  • Boiling Point:866.1 °C at 760 mmHg
  • Flash Point:477.6 °C
Encyclopedia Safety and Handling MSDS NMR Spectrum Synthesis Route 146 Suppliers Request For Quotation
Unii-4U07F515lg; 496775-62-3 structural formula
Unii-4U07F515lg
  • Eltrombopag is a thrombopoietin-receptor agonist used to treat low blood platelet counts with chronic immune thrombocytopenia.
  • CAS No: 496775-62-3
  • Molecular Weight: 564.63274
  • Molecular Formula:C29H36N6O6
Encyclopedia Safety and Handling MSDS 91 Suppliers Request For Quotation
Pomalidomide; 19171-19-8 structural formula
Pomalidomide
  • Yellow SolidChEBI: An aromatic amine that is thalidomide substituted at position 4 on the isoindole ring system by an amino group. Used for the treatment of multiple myeloma in patients who failed to respond to previous therapies.Pomalidomide inhibits LPS-induced TNF-α release with IC50 of 13 nM in..
  • CAS No: 19171-19-8
  • Molecular Weight: 273.24
  • Molecular Formula:C13H11N3O4
  • Density:1.57
  • Boiling Point:582.9°Cat760mmHg
  • Flash Point:306.3°C
Encyclopedia Safety and Handling MSDS 142 Suppliers Request For Quotation
ACP196; 1420477-60-6 structural formula
ACP196
  • Acalabrutinib, is an experimental anti-cancer drug and a selective Bruton's tyrosine kinase (BTK) inhibitor. This kinase transmits signals from B-cell Receptor (BCR), and thus any genetic BTK mutation causes B-Cell immunodeficiency. Therefore, BTK inhibitors targeting B-cell signaling has shown grea..
  • CAS No: 1420477-60-6
  • Molecular Weight: 465.517
  • Molecular Formula:C26H23N7O2
  • Density:1.37±0.1 g/cm3(Predicted)
Encyclopedia Safety and Handling MSDS 32 Suppliers Request For Quotation
Potassium iodide; 7681-11-0 structural formula
Potassium iodide
  • Colorless or white cubic crystals or granules; becomes yellowish when exposed to bright light due to photochemical decomposition liberating traces of free iodine; density 3.13 g/cm3; melts at 681°C; vaporizes at 1,330°C; highly soluble in water, ~140 g/100mL at 20°C; aqueous solution readily dissolv..
  • CAS No: 7681-11-0
  • Molecular Weight: 166.00277
  • Molecular Formula:IK
  • Density:3.13
  • Boiling Point:1330℃
  • Flash Point:1330°C
Encyclopedia Safety and Handling MSDS Synthesis Route 649 Suppliers Request For Quotation
Tenofovir disoproxil fumarate; 202138-50-9 structural formula
Tenofovir disoproxil fumarate
  • Tenofovir Disoproxil Fumarate is a nucleotide reverse transcriptase inhibitor used to treat HIV and chronic Hepatitis B.
  • CAS No: 202138-50-9
  • Molecular Weight: 635.514921
  • Molecular Formula:C23H34N5O14P
  • Density:1.45
  • Boiling Point:642.7 °C at 760 mmHg
  • Flash Point:342.5 °C
Encyclopedia Safety and Handling MSDS Synthesis Route 295 Suppliers Request For Quotation
Glipizide; 29094-61-9 structural formula
Glipizide
  • Crystalline Solid
  • CAS No: 29094-61-9
  • Molecular Weight: 445.53518
  • Molecular Formula:C21H27N5O4S
  • Density:1.34
  • Boiling Point:676.0±65.0 °C at 760 mmHg
  • Flash Point:362.6±34.3 °C
Encyclopedia Safety and Handling MSDS NMR Spectrum 321 Suppliers Request For Quotation
Melatonine; 73-31-4 structural formula
Melatonine
  • Melatonin is a hormone made by the pineal gland that can activates melatonin receptor. Melatonin plays a role in sleep and possesses important antioxidative and anti-inflammatory properties.
  • CAS No: 73-31-4
  • Molecular Weight: 232.28
  • Molecular Formula:C13H16N2O2
  • Density:1.175
  • Boiling Point:512.8°C at 760 mmHg
  • Flash Point:264°C
Encyclopedia Safety and Handling MSDS Synthesis Route 652 Suppliers Request For Quotation
Ubidecarenone; 303-98-0 structural formula
Ubidecarenone
  • Coenzyme Q10 is an essential cofactor of the electron transport chain and a potent antioxidant agent.
  • CAS No: 303-98-0
  • Molecular Weight: 863.3435
  • Molecular Formula:C59H90O4
  • Density:0.97
  • Boiling Point:869 °C at 760mmHg
  • Flash Point:324.5 °C
Encyclopedia Safety and Handling MSDS NMR Spectrum Synthesis Route 840 Suppliers Request For Quotation
ISOPRINOSINE; 36703-88-5 structural formula
ISOPRINOSINE
  • Inosine pranobex is a potent, broad-spectrum antiviral compound for HIV infection. Inosine pranobex is an immunopotentiator[1].
  • CAS No: 36703-88-5
  • Molecular Weight: 1115.23252
  • Molecular Formula:C52H78N10O17
  • Boiling Point:732.8 °C at 760 mmHg
  • Flash Point:397 °C
Encyclopedia Safety and Handling MSDS NMR Spectrum 162 Suppliers Request For Quotation
Butyl levulinate; 2052-15-5 structural formula
Butyl levulinate
  • CLEAR YELLOW TO ORANGE-BROWN LIQUID Butyl levulinate has a sweet and slightly pungent caramellic odor with fruity undertones; mild sweet caramellicherbaceoustaste; bitter taste.
  • CAS No: 2052-15-5
  • Molecular Weight: 172.22154
  • Molecular Formula:C9H16O3
  • Density:0.974
  • Boiling Point:106-108℃ (5.5 mmHg)
  • Flash Point:91℃
Encyclopedia Safety and Handling MSDS NMR Spectrum Synthesis Route 69 Suppliers Request For Quotation
DL-SULFORAPHANE; 4478-93-7 structural formula
DL-SULFORAPHANE
  • Sulforaphane is an isothiocyanate present naturally in widely consumed vegetables; has shown anticancer and cardioprotective activities.
  • CAS No: 4478-93-7
  • Molecular Weight: 177.28764
  • Molecular Formula:C6H11NOS2
  • Density:1.17
  • Boiling Point:368.2°Cat760mmHg
  • Flash Point:176.5°C
Encyclopedia Safety and Handling MSDS Synthesis Route 85 Suppliers Request For Quotation
Mycophenolic acid; 24280-93-1 structural formula
Mycophenolic acid
  • Mycophenolic acid is an an immunosuppresant drug and has potent anti-proliferative activity.Target: OthersMycophenolic acid(MPA) is an immunosuppressant drug used to prevent rejection in organ transplantation. It inhibits an enzyme needed for the growth of T cells and B cells. MPA did not block the ..
  • CAS No: 24280-93-1
  • Molecular Weight: 320.341
  • Molecular Formula:C17H20O6
  • Density:1.29
  • Boiling Point:611.6°Cat760mmHg
  • Flash Point:225.8°C
Encyclopedia Safety and Handling MSDS 225 Suppliers Request For Quotation
Mizoribine; 50924-49-7 structural formula
Mizoribine
  • Mizoribine(NSC 289637; HE 69; β-Bredinin) is an immunosuppressive agents (IC50=100 uM) that inhibit the proliferation of lymphocytes selectively, via inhibition of IMPDH.IC50 Value:Target: IMPDHin vitro: Unlike azathioprine, Mizoribine is not taken up by nucleic acids in the cell. Instead, after ph..
  • CAS No: 50924-49-7
  • Molecular Weight: 259.22
  • Molecular Formula:C9H13N3O6
  • Density:1.4155 (rough estimate)
  • Boiling Point:402.47°C (rough estimate)
  • Flash Point:410.9 °C
Encyclopedia Safety and Handling MSDS Synthesis Route 103 Suppliers Request For Quotation
Guaiacol; 90-05-1 structural formula
Guaiacol
  • Guaiacol, a phenolic compound isolated from Guaiac resin, inhibits LPS-stimulated COX-2 expression and NF-κB activation[1]. Anti-inflammatory activity[1].
  • CAS No: 90-05-1
  • Molecular Weight: 124.139
  • Molecular Formula:C7H8O2
  • Density:1.09 g/mL at 20 °C
  • Boiling Point:less than -4° F (NTP, 1992)
  • Flash Point:165° F (NTP, 1992)
Encyclopedia Safety and Handling MSDS 355 Suppliers Request For Quotation
CREMOPHOR (R) A25; 68439-49-6 structural formula
CREMOPHOR (R) A25
  • Ceteareth-25 is an emulsifier that can be used as leveling agent, retarder, emulsifier for glass fiber industry, chemical fiber spinning oil component, emulsifier for cosmetics and ointment production in printing and dyeing industry. Household and industrial cleaning agents. In the chemical fiber in..
  • CAS No: 68439-49-6
  • Molecular Weight:
  • Molecular Formula:C18H38O
  • Density:1.1±0.1 g/cm3
  • Boiling Point:223.6±35.0 °C at 760 mmHg
  • Flash Point:243℃
Encyclopedia Safety and Handling 109 Suppliers Request For Quotation
Stavudine; 3056-17-5 structural formula
Stavudine
  • Stavudine is a nucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV.Target: HIV RT; NRTIsStavudine is a dideoxynucleoside analog that inhibits reverse transcriptase and has in vitro activity against HIV. Stavudine is an analog of thymidine. It is phosphorylated..
  • CAS No: 3056-17-5
  • Molecular Weight: 224.216
  • Molecular Formula:C10H12N2O4
  • Density:1.374
  • Boiling Point:440.6±55.0 °C at 760 mmHg
  • Flash Point:220.3±31.5 °C
Encyclopedia Safety and Handling MSDS Synthesis Route 271 Suppliers Request For Quotation
Cyclosporin A; 59865-13-3 structural formula
Cyclosporin A
  • Cyclosporin A is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of calcineurin with an IC50 of 5 nM.
  • CAS No: 59865-13-3
  • Molecular Weight: 1202.635
  • Molecular Formula:C62H111N11O12
  • Density:1.016
  • Boiling Point:1293.8°C at 760 mmHg
  • Flash Point:736.3°C
Encyclopedia Safety and Handling MSDS NMR Spectrum 331 Suppliers Request For Quotation
Aztreonam; 78110-38-0 structural formula
Aztreonam
  • Aztreonam is a synthetic monocyclic beta-lactam antibiotic, which has a very high affinity for penicillin-binding protein 3 (PBP-3).Target: Penicillin-binding proteins 3 (PBP-3)Aztreonam is a synthetic monocyclic beta-lactam antibiotic (a monobactam), with the nucleus based on a simpler monobactam i..
  • CAS No: 78110-38-0
  • Molecular Weight: 435.426
  • Molecular Formula:C13H17N5O8S2
  • Density:1.83
Encyclopedia Safety and Handling MSDS Synthesis Route 357 Suppliers Request For Quotation
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