Related Searches: 19-Norpregn-4-en-20-yn-3-one,17-hydroxy-, (17a)-, Estr-4-en-3-one,17-hydroxy-, (17b)-, Androst-5-en-17-one,3-(acetyloxy)-, (3b)-, Androstan-3-one,17-hydroxy-17-methyl-, (5a,17b)-, Androstan-3-one,17-hydroxy-1-methyl-, (1a,5a,17b)-, View all

19-Norpregn-5(10)-en-20-yn-3-one,17-hydroxy-7-methyl-, (7a,17a)-(CAS No. 5630-53-5)

19-Norpregn-5(10)-en-20-yn-3-one,17-hydroxy-7-methyl-, (7a,17a)- C21H28O2 (cas 5630-53-5) Molecular Structure

5630-53-5 Structure

Identification and Related Records

【Name】
19-Norpregn-5(10)-en-20-yn-3-one,17-hydroxy-7-methyl-, (7a,17a)-
【CAS Registry number】
5630-53-5
【Synonyms】
19-Nor-17a-pregn-5(10)-en-20-yn-3-one, 17-hydroxy-7a-methyl- (7CI,8CI)
(7a,17a)-17-Hydroxy-7-methyl-19-norpregn-5(10)-en-20-yn-3-one
7a-Methyl-17a-ethynyl-17b-hydroxy-5(10)-estren-3-one
7a-Methyl-D5,10-norethindrone
Livial
Liviella
Org OD 14
【EINECS(EC#)】
227-069-1
【Molecular Formula】
C21H28O2 (Products with the same molecular formula)
【Molecular Weight】
312.44582
【Inchi】
InChI=1S/C21H28O2/c1-4-21(23)10-8-18-19-13(2)11-14-12-15(22)5-6-16(14)17(19)7-9-20(18,21)3/h1,13,17-19,23H,5-12H2,2-3H3/t13-,17-,18+,19-,20+,21+/m1/s1
【InChIKey】
WZDGZWOAQTVYBX-XOINTXKNSA-N
【Canonical SMILES】
CC1CC2=C(CCC(=O)C2)C3C1C4CCC(C4(CC3)C)(C#C)O
【Isomers smiles】
C[C@@H]1CC2=C(CCC(=O)C2)[C@@H]3[C@@H]1[C@@H]4CC[C@]([C@]4(CC3)C)(C#C)O
【MOL File】
5630-53-5.mol

Chemical and Physical Properties

【Appearance】
white to off-white crystalline powder
【Density】
1.13g/cm3
【Melting Point】
163 - 169 C
【Boiling Point】
447.4°Cat760mmHg
【Refractive Index】
105 ° (C=0.54, CH2Cl2/Et2O)
【Flash Point】
190.6°C
【Water】
practically insoluble (soluble in chloroform, methanol)
【Solubilities】
practically insoluble (soluble in chloroform, methanol)
【Storage temp】
2-8°C
【Computed Properties】
Molecular Weight:312.44582 [g/mol]
Molecular Formula:C21H28O2
XLogP3-AA:2.4
H-Bond Donor:1
H-Bond Acceptor:2
Rotatable Bond Count:1
Tautomer Count:8
Exact Mass:312.20893
MonoIsotopic Mass:312.20893
Topological Polar Surface Area:37.3
Heavy Atom Count:23
Formal Charge:0
Complexity:636
Isotope Atom Count:0
Defined Atom Stereocenter Count:6
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:1
Feature 3D Acceptor Count:2
Feature 3D Donor Count:1
Feature 3D Hydrophobe Count:1
Feature 3D Ring Count:4
Effective Rotor Count:2
Conformer Sampling RMSD:0.6
CID Conformer Count:1

Safety and Handling

【Hazard Codes】
N:;
【Risk Statements】
R51/53
【Safety Statements 】
22-24/25-61
【Safety】
Hazard Codes:N
Risk Statements:51/53
51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
Safety Statements:22-24/25-61
22:Do not breathe dust
24/25:Avoid contact with skin and eyes
61:Avoid release to the environment. Refer to special instructions safety data sheet
RIDADR:UN 3077 9/PG 3
【Transport】
HAZARD
【Specification】

White Solid
usageEng:A synthetic steroid with weak estrogenic, androgenic and progestogenic activity. A pharamceutical used in the treatment of menopausal syndrome
Safety Statements:22-24/25-61
22:Do not breathe dust
24/25:Avoid contact with skin and eyes
61:Avoid release to the environment. Refer to special instructions safety data sheet

Use and Manufacturing

【Usage】

A synthetic steroid with weak estrogenic, androgenic and progestogenic activity. A pharamceutical used in the treatment of menopausal syndrome

Biomedical Effects and Toxicity

【Pharmacological Action】
- These compounds stimulate anabolism and inhibit catabolism. They stimulate the development of muscle mass, strength, and power.
- Compounds which inhibit or antagonize the biosynthesis or actions of androgens.
- Drugs used in the treatment of acute or chronic vascular HYPERTENSION regardless of pharmacological mechanism. Among the antihypertensive agents are DIURETICS; (especially DIURETICS, THIAZIDE); ADRENERGIC BETA-ANTAGONISTS; ADRENERGIC ALPHA-ANTAGONISTS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; CALCIUM CHANNEL BLOCKERS; GANGLIONIC BLOCKERS; and VASODILATOR AGENTS.
- Antineoplastic agents that are used to treat hormone-sensitive tumors. Hormone-sensitive tumors may be hormone-dependent, hormone-responsive, or both. A hormone-dependent tumor regresses on removal of the hormonal stimulus, by surgery or pharmacological block. Hormone-responsive tumors may regress when pharmacologic amounts of hormones are administered regardless of whether previous signs of hormone sensitivity were observed. The major hormone-responsive cancers include carcinomas of the breast, prostate, and endometrium; lymphomas; and certain leukemias. (From AMA Drug Evaluations Annual 1994, p2079)
- Substances that possess antiestrogenic actions but can also produce estrogenic effects as well. They act as complete or partial agonist or as antagonist. They can be either steroidal or nonsteroidal in structure.
【Therapeutic Uses】
A synthetic steroid with weak estrogenic, androgenic and progestogenic activity. A pharamceutical used in the treatment of menopausal syndrome

Supplier Location

Top Suppliers

Diamond member Nanjing Bangnuo Biotechnology Co., Ltd
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-1732-7098554
Diamond member Wuhan Fortuna Chemical Co., Ltd.
Country:ChinaChina
Business Type:Manufacturer
Telephone:0086-27-59207850
Diamond member Wuhan H.X.K Fine Chemicals Co.,LTD
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-27-59721024
Diamond member Hubei XinRunde Chemical Co., Ltd
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-188-74586545
Diamond member Jinlan Pharm-Drugs Technology Co., Limited
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-571-85829152
Diamond member Yichang yongnuopharm co.,ltd
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-717-4128488
Diamond member MOSINTER GROUP LIMITED
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-574-89212210
Diamond member AOPHARM
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-311-66600578
Diamond member Hangzhou J&H Chemical Co., Ltd
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-571-87396430
Shanghai Forever Synthesis Co.,Ltd.
Country:ChinaChina
Business Type:Distributor/Wholesaler
Telephone:86-21-61124658

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