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Home> Hot Product Listed 1   > 1-Piperazineethanol,4-[3-[(3Z)-2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-, hydrochloride(...
8006-54-0 structure

1-Piperazineethanol,4-[3-[(3Z)-2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-, hydrochloride(1:2)

CAS No.:8006-54-0
Molecular Formula:C21H34N2O (isomer)
Names and Identifiers
Synonyms

(Z)-4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride 4-[3-[(3Z)-2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol Hydrochloride a-Flupenthixol Hydrochloride CIS-(Z)-FLUPENTHIXOL DIHYDROCHLORIDE ANT IPSYCHOTIC,NEUROL cis-(Z)-Flupentixol Dihydrochloride cis-Flupentixol Hydrochloride Metamin

Properties
Appearance
white or off-white solid
Melting Point
38-40℃
Solubility
soluble in water
Color/Form
white or off-white
Storage temp
Desiccate at RT
Safety and Handling
Safety Statements
S24/25
Safety

Safty information about Flupentihxol Hydrochloride (CAS NO.2413-38-9) is:
Poison by subcutaneous and intravenous routes. Moderately toxic by ingestion. When heated to decomposition it emits toxic fumes of F, SOx, NOx, and HCl. 
Hazard Codes:
HarmfulXn
Risk Statements:
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements:
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection.
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: TL9900000

Toxicity
Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 94mg/kg (94mg/kg) behavioral: sleep Acta Pharmacologica et Toxicologica. Vol. 19, Pg. 87, 1962.
mouse LD50 oral 423mg/kg (423mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 90, 1973.
mouse LD50 subcutaneous 425mg/kg (425mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 90, 1973.
rat LD50 intravenous 37mg/kg (37mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 90, 1973.
rat LD50 oral 791mg/kg (791mg/kg)   Drugs in Japan Vol. 6, Pg. 704, 1982.
rat LD50 subcutaneous 258mg/kg (258mg/kg)   Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 4, Pg. 90, 1973.
Specification

Light Brown Solid
usageEng:Neuroleptic agent related structurally to thiothixene. Antipsychotic; neuroleptic agent; dopamine receptor antagonist.
Safety Statements:36/37/39
36/37/39:Wear suitable protective clothing, gloves and eye/face protection
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