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Home> Hot Product Listed T   > Triethylene glycol

Triethylene glycol

CAS No.:112-27-6
EINECS(EC#):203-953-2
Molecular Weight:150.17
Molecular Formula:C6H14O4 (Products with the same molecular formula)
MOL File:112-27-6.mol
Names and Identifiers
Synonyms

Triethylene glycol TriglycolTEG triethylene glycol anhydrous 2,2-(ethylenedioxy)diethanol Trigol 95+ % (GLC) Trigol

Inchi
InChI=1/C6H14O4/c7-1-3-9-5-6-10-4-2-8/h7-8H,1-6H2
InChkey
ZIBGPFATKBEMQZ-UHFFFAOYSA-N
Canonical Smiles
C(COCCOCCO)O
Properties
Appearance
Clear liquid
Density
1.124
Melting Point
-7℃
Boiling Point
285℃
Vapour
0.000268mmHg at 25°C
Refractive Index
1.4545-1.4565
Flash Point
165℃
Water
SOLUBLE
Solubilities
soluble in water
Color/Form
Colorless liquid
Stability
Stable. Combustible. Incompatible with strong oxidizing agents.
HS Code
29094919
Storage temp
Store in a cool, dry place. Keep containers tightly closed.
Spectral properties
Index of refraction: 1.4531 at 15 deg C/D
IR: 6272 (Coblentz Society Spectral Collection)
1H NMR: 5543 (Sadtler Research Laboratories Spectral Collection)
MASS: 61420 (NIST/EPA/MSDC Mass Spectral database, 1990 version)
Safety and Handling
Hazard Codes
Xi:Irritant
Risk Statements
R36/37/38
Safety Statements
S26;S36
PackingGroup
Z01
Sensitive
Hygroscopic
Skin, Eye, and Respiratory Irritations
... /Irritant to/ ... eyes
Transport
225kgs
Fire Fighting Procedures
Alcohol foam, dry chemical
Fire Potential
Combustible when exposed to heat or flame.
... It is stable chemically, does not present hazard due to flammability, except possibly at high temperatures or where fogs or mists are involved.
Formulations/Preparations
Udex grades /Dow Chemical/
Clear liquid grades 99% /Eastman Chemical/
Grade: Technical, CP.
Exposure Standards and Regulations
Triethylene glycol is an indirect food additive for use only as a component of adhesives.
Reactivities and Incompatibilities
Can react with oxidizing materials.
Glycol ethers, glycols, ketones, and alcohols undergo violent decomposition in contact with 68-72% perchloric acid
Other Preventative Measures
Air Treatment: Do not use in nurseries or rooms where infants, ill or aged patients are confined; food, food contact surfaces and utensils should be protected from exposure to the spray or rinsed with ptable water before use. Spray away from drapes, walls, plastic, vinyl, painted or varnished surfaces.
SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.
Protective Equipment and Clothing
... /Irritant to/ ... eyes
Specification

The IUPAC name of?Triethylene glycol is?2-[2-(2-hydroxyethoxy)ethoxy]ethanol. With the?CAS registry number 112-27-6,?it is also named as 2,2'-(1,2-Ethanediylbis(oxy))bisethanol.?The product's categories are?ethylene glycol; ethylene glycols; ethylene glycols & monofunctional ethylene glycols.?It is colorless, odorless, viscous and hygroscopic liquid which is miscible with water and?ethanol, slightly soluble in ether, almost insoluble in petroleum ether. It is?slightly toxic and?combustible. Additionally,?Triethylene glycol is non-corrosive to metal and do not react with?the majority?plastic and rubber. When not use, it should sealed in the container which must placed in the cool and dry aera.

The other characteristics of this product can be summarized as:?(1)ACD/BCF (pH 5.5): 1; (2)ACD/BCF (pH 7.4): 1; (3)ACD/KOC (pH 5.5): 2.29; (4)ACD/KOC (pH 7.4): 2.29; (5)#H bond acceptors: 4; (6)#H bond donors: 2; (7)#Freely Rotating Bonds: 9; (8)Index of Refraction: 1.45; (9)Molar Refractivity: 36.4 cm3; (10)Molar Volume: 135.3 cm3; (11)Polarizability: 14.43×10-24 cm3; (12)Surface Tension: 41.6 dyne/cm; (13)Enthalpy of Vaporization: 61.18 kJ/mol; (14)Vapour Pressure: 0.000268 mmHg at 25°C; (15)Rotatable Bond Count: 7; (16)Exact Mass: 150.089209; (17)MonoIsotopic Mass: 150.089209; (18)Topological Polar Surface Area: 58.9; (19)Heavy Atom Count: 10.

Preparation of Triethylene glycol:?It is obtained, with diethylene glycol, as a by-product in the manufacture of ethylene glycol from hydrolysis of ethylene oxide.
????????? 6CH2CH2O + 3H2O → HOCH2CH2OH + HOCH2CH2OCH2CH2OH
???????????????????? + HOCH2CH2OCH2CH2OCH2CH2OH
It is separated from the ethylene glycol and diethylene glycol by vacuum distillation.

Uses of Triethylene glycol: It?is not only?used as a plasticizer for vinyl, but also?used in Air-Sanitizer products. When aerosolized, it?acts as a disinfectant. Additionally, Triethylene glycol?is also used as liquid desiccants for natural gas and in air conditioning systems. Furthermore,?it is an additive for hydraulic fluids and brake fluids and used as a base for "smoke machine" fluid in the entertainment industry.?

When you are using this chemical, please be cautious about it as the following:
It is irritating to eyes, respiratory system and skin.?In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?If you want to contact this product, you must wear suitable protective clothing.

People can use the following data to convert to the molecule structure.?
1. SMILES:OCCOCCOCCO
2.?InChI:InChI=1/C6H14O4/c7-1-3-9-5-6-10-4-2-8/h7-8H,1-6H2

The following are the toxicity data which has been tested.

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous > 4500mg/kg (4500mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1536, 1968.
?
guinea pig LD50 intravenous 10600mg/kg (10600mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1536, 1968.
?
guinea pig LD50 oral 7900mg/kg (7900mg/kg) ? Journal of Industrial Hygiene and Toxicology. Vol. 28, Pg. 40, 1946.
human LDLo oral 5gm/kg (5000mg/kg) ? Food and Cosmetics Toxicology. Vol. 17, Pg. 913, 1979.
mammal (species unspecified) LD50 oral 8150mg/kg (8150mg/kg) ? Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(4), Pg. 86, 1974.
mouse LD50 intraperitoneal 8141mg/kg (8141mg/kg) LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA

BLOOD: CHANGES IN SPLEEN

KIDNEY, URETER, AND BLADDER: CHANGES IN BOTH TUBULES AND GLOMERULI
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 6, Pg. 342, 1947.
mouse LD50 intravenous 6500mg/kg (6500mg/kg) ? Journal of Pharmacology and Experimental Therapeutics. Vol. 65, Pg. 89, 1939.
mouse LD50 subcutaneous 8750mg/kg (8750mg/kg) ? Journal of Pharmacology and Experimental Therapeutics. Vol. 65, Pg. 89, 1939.
mouse LDLo oral 18500mg/kg (18500mg/kg) ? Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 1186, 1966.
rabbit LD50 intravenous 1900mg/kg (1900mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1536, 1968.
?
rabbit LD50 oral 8400mg/kg (8400mg/kg) ? Journal of Industrial Hygiene and Toxicology. Vol. 28, Pg. 40, 1946.
rabbit LD50 skin > 20mL/kg (20mL/kg) ? "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 731, 1969.
rat LD50 intravenous 11700mg/kg (11700mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1536, 1968.
?
rat LD50 oral 17gm/kg (17000mg/kg) ? Journal of Industrial Hygiene and Toxicology. Vol. 28, Pg. 40, 1946.
rat LDLo intramuscular 8400mg/kg (8400mg/kg) ? Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 29, Pg. 5, 1940.

Octanol/Water Partition Coefficient
log Kow = -1.98
Report

The IUPAC name of?Triethylene glycol is?2-[2-(2-hydroxyethoxy)ethoxy]ethanol. With the?CAS registry number 112-27-6,?it is also named as 2,2'-(1,2-Ethanediylbis(oxy))bisethanol.?The product's categories are?ethylene glycol; ethylene glycols; ethylene glycols & monofunctional ethylene glycols.?It is colorless, odorless, viscous and hygroscopic liquid which is miscible with water and?ethanol, slightly soluble in ether, almost insoluble in petroleum ether. It is?slightly toxic and?combustible. Additionally,?Triethylene glycol is non-corrosive to metal and do not react with?the majority?plastic and rubber. When not use, it should sealed in the container which must placed in the cool and dry aera.

The other characteristics of this product can be summarized as:?(1)ACD/BCF (pH 5.5): 1; (2)ACD/BCF (pH 7.4): 1; (3)ACD/KOC (pH 5.5): 2.29; (4)ACD/KOC (pH 7.4): 2.29; (5)#H bond acceptors: 4; (6)#H bond donors: 2; (7)#Freely Rotating Bonds: 9; (8)Index of Refraction: 1.45; (9)Molar Refractivity: 36.4 cm3; (10)Molar Volume: 135.3 cm3; (11)Polarizability: 14.43×10-24 cm3; (12)Surface Tension: 41.6 dyne/cm; (13)Enthalpy of Vaporization: 61.18 kJ/mol; (14)Vapour Pressure: 0.000268 mmHg at 25°C; (15)Rotatable Bond Count: 7; (16)Exact Mass: 150.089209; (17)MonoIsotopic Mass: 150.089209; (18)Topological Polar Surface Area: 58.9; (19)Heavy Atom Count: 10.

Preparation of Triethylene glycol:?It is obtained, with diethylene glycol, as a by-product in the manufacture of ethylene glycol from hydrolysis of ethylene oxide.
????????? 6CH2CH2O + 3H2O → HOCH2CH2OH + HOCH2CH2OCH2CH2OH
???????????????????? + HOCH2CH2OCH2CH2OCH2CH2OH
It is separated from the ethylene glycol and diethylene glycol by vacuum distillation.

Uses of Triethylene glycol: It?is not only?used as a plasticizer for vinyl, but also?used in Air-Sanitizer products. When aerosolized, it?acts as a disinfectant. Additionally, Triethylene glycol?is also used as liquid desiccants for natural gas and in air conditioning systems. Furthermore,?it is an additive for hydraulic fluids and brake fluids and used as a base for "smoke machine" fluid in the entertainment industry.?

When you are using this chemical, please be cautious about it as the following:
It is irritating to eyes, respiratory system and skin.?In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?If you want to contact this product, you must wear suitable protective clothing.

People can use the following data to convert to the molecule structure.?
1. SMILES:OCCOCCOCCO
2.?InChI:InChI=1/C6H14O4/c7-1-3-9-5-6-10-4-2-8/h7-8H,1-6H2

The following are the toxicity data which has been tested.

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
dog LD50 intravenous > 4500mg/kg (4500mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1536, 1968.
?
guinea pig LD50 intravenous 10600mg/kg (10600mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1536, 1968.
?
guinea pig LD50 oral 7900mg/kg (7900mg/kg) ? Journal of Industrial Hygiene and Toxicology. Vol. 28, Pg. 40, 1946.
human LDLo oral 5gm/kg (5000mg/kg) ? Food and Cosmetics Toxicology. Vol. 17, Pg. 913, 1979.
mammal (species unspecified) LD50 oral 8150mg/kg (8150mg/kg) ? Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 39(4), Pg. 86, 1974.
mouse LD50 intraperitoneal 8141mg/kg (8141mg/kg) LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA

BLOOD: CHANGES IN SPLEEN

KIDNEY, URETER, AND BLADDER: CHANGES IN BOTH TUBULES AND GLOMERULI
Federation Proceedings, Federation of American Societies for Experimental Biology. Vol. 6, Pg. 342, 1947.
mouse LD50 intravenous 6500mg/kg (6500mg/kg) ? Journal of Pharmacology and Experimental Therapeutics. Vol. 65, Pg. 89, 1939.
mouse LD50 subcutaneous 8750mg/kg (8750mg/kg) ? Journal of Pharmacology and Experimental Therapeutics. Vol. 65, Pg. 89, 1939.
mouse LDLo oral 18500mg/kg (18500mg/kg) ? Pesticide Chemicals Official Compendium, Association of the American Pesticide Control Officials, Inc., 1966. Vol. -, Pg. 1186, 1966.
rabbit LD50 intravenous 1900mg/kg (1900mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1536, 1968.
?
rabbit LD50 oral 8400mg/kg (8400mg/kg) ? Journal of Industrial Hygiene and Toxicology. Vol. 28, Pg. 40, 1946.
rabbit LD50 skin > 20mL/kg (20mL/kg) ? "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 731, 1969.
rat LD50 intravenous 11700mg/kg (11700mg/kg) ? Arzneimittel-Forschung. Drug Research. Vol. 18, Pg. 1536, 1968.
?
rat LD50 oral 17gm/kg (17000mg/kg) ? Journal of Industrial Hygiene and Toxicology. Vol. 28, Pg. 40, 1946.
rat LDLo intramuscular 8400mg/kg (8400mg/kg) ? Journal of the American Pharmaceutical Association, Scientific Edition. Vol. 29, Pg. 5, 1940.

Disposal Methods
SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.
Reach Info
This substance has been officially registered by enterprises.
ECHA (EU chemicals Management Agency) published the completed registration file as follows:
Completed registration file:
Registered as ubmitted Total tonnage band  
FULL JOINT 10000_100000 view >
Registered companies:
Registrant / Supplier details Latest dossier received
B-Lands Consulting (8111117-5) 2016
BASF Antwerpen N.V. 2015
BASF SE 2015
more >
MSDS

Download/Modify | Technical supported by XiXisys.com. For US version, EU version (23 languages) and more, please refer to xixisys.com/en/sds/search

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017

1.Identification

1.1 GHS Product identifier

Product name triethylene glycol

1.2 Other means of identification

Product number -
Other names Triethylene glycol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Adsorbents and absorbents,Functional fluids (closed systems),Functional fluids (open systems),Intermediates,Processing aids, specific to petroleum production,Solvents (for cleaning or degreasing),Solvents (which become part of product formulation or mixture)
Uses advised against no data available

1.4 Supplier's details

Company WWW.GuideChem.COM
Address 8F, Block C, No.3 Building, Zijin Plaza, No.701, Gudun Road, Hangzhou, Zhejiang 310030, China
Telephone +86-571-89739798
Fax 86(21)54365166

1.5 Emergency phone number

Emergency phone number +86-571-89739798
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Not classified.

2.2 GHS label elements, including precautionary statements

Pictogram(s) No symbol.
Signal word

No signal word.

Hazard statement(s)

none

Precautionary statement(s)
Prevention

none

Response

none

Storage

none

Disposal

none

2.3 Other hazards which do not result in classification

none

3.Composition/information on ingredients

3.1 Substances

Chemical name Common names and synonyms CAS number EC number Concentration
triethylene glycol triethylene glycol 112-27-6 none 100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Remove contaminated clothes. Rinse skin with plenty of water or shower.

In case of eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

If swallowed

Rinse mouth.

4.2 Most important symptoms/effects, acute and delayed

Vapor and liquid are unlikely to cause harm. (USCG, 1999)

4.3 Indication of immediate medical attention and special treatment needed, if necessary

Basic treatment: Establish a patent airway (oropharyngeal or nasopharyngeal airway, if needed). Suction if necessary. Watch for signs of respiratory insufficiency and assist ventilations if necessary. Administer oxygen by nonrebreather mask at 10 to 15 L/min. Monitor for pulmonary edema and treat if necessary ... . Monitor for shock and treat if necessary ... . Anticipate seizures and treat if necessary ... . For eye contamination, flush eyes immediately with water. Irrigate each eye continuously with 0.9% saline (NS) during transport ... . Do not use emetics. For ingestion, rinse mouth and administer 5 ml/kg up to 200 ml of water for dilution if the patient can swallow, has a strong gag reflex, and does not drool. Administer activated charcoal ... . /Ethylene glycol, glycols, and related compounds/

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Alcohol foam, dry chemical

5.2 Specific hazards arising from the chemical

This chemical is combustible.

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Collect leaking and spilled liquid in sealable containers as far as possible. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

6.3 Methods and materials for containment and cleaning up

Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state Clear liquid
Colour Colorless liquid
Odour Practically odorless
Melting point/ freezing point 118\u00b0C(lit.)
Boiling point or initial boiling point and boiling range 276\u00b0C(lit.)
Flammability Combustible.
Lower and upper explosion limit / flammability limit Lower flammable limit: 0.9% by volume; Upper flammable limit: 9.2% by volume
Flash point 174\u00b0C(lit.)
Auto-ignition temperature 371.11\u00b0C (USCG, 1999)
Decomposition temperature no data available
pH no data available
Kinematic viscosity 47.8 cP at 20\u00b0C
Solubility In water:SOLUBLE
Partition coefficient n-octanol/water (log value) log Kow = -1.98
Vapour pressure <0.01 mm Hg ( 20 \u00b0C)
Density and/or relative density 1.124
Relative vapour density 5.2 (vs air)
Particle characteristics no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

Combustible when exposed to heat or flame.TRIETHYLENE GLYCOL is a ether-alcohol derivative. The ether being relatively unreactive. Flammable and/or toxic gases are generated by the combination of alcohols with alkali metals, nitrides, and strong reducing agents. They react with oxoacids and carboxylic acids to form esters plus water. Oxidizing agents convert alcohols to aldehydes or ketones. Alcohols exhibit both weak acid and weak base behavior. They may initiate the polymerization of isocyanates and epoxides. Reacts with strong oxidants. [Handling Chemicals Safely 1980. p. 932].

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

Can react with oxidizing materials.

10.6 Hazardous decomposition products

When heated to decomposition it emits acrid smoke and irritating fumes.

11.Toxicological information

Acute toxicity

  • Oral: LD50 Mouse oral 18,500 mg/kg
  • Inhalation: LC50 Rat (Sprague-Dawley) inhalation >3.9 mg/L/4 hr
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available

Carcinogenicity

no data available

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

  • Toxicity to fish: LC50 Pimephales promelas (Fathead minnow) 59.9 g/L/96 hr (confidence limit 56.2 - 63.7 g/L), flow-through bioassay with measured concentrations, dissolved oxygen 7.2 mg/L, hardness 44.2 mg/L calcium carbonate, alkalinity 38.5 mg/L calcium carbonate, and pH 7.3
  • Toxicity to daphnia and other aquatic invertebrates: LC50 Daphnia magna (Water flea) 35000 ug/L/48 hr; static
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available

12.2 Persistence and degradability

AEROBIC: Aerobic river die-away tests, utilizing several different sources of freshwater, have demonstrated that triethylene glycol should biodegrade rapidly in the environment(1). At 20\u00b0C, the degradation of 10 mg/L triethylene glycol was complete within 7-11 days(1). 25 to 92% of the theoretical BOD was reached within 4 weeks incubation during the MITI test using a sludge inoculum; these results were on an upward trend by the end of the test(2) indicating that acclimation may be important for this compound(SRC). Triethylene glycol degraded 85% of theoretical BOD (1.6 gm/gm) after 20 days at 20\u00b0C(3).

12.3 Bioaccumulative potential

An estimated BCF of 3 was calculated in fish for triethylene glycol(SRC), using an estimated log Kow of -1.75(1) and a regression-derived equation(2). According to a classification scheme(3), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

12.4 Mobility in soil

Using a structure estimation method based on molecular connectivity indices(1), the Koc of triethylene glycol can be estimated to be 10(SRC). According to a classification scheme(2), this estimated Koc value suggests that triethylene glycol is expected to have very high mobility in soil(SRC).

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods

Product

The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: UN2735 IMDG: UN2735 IATA: UN2735

14.2 UN Proper Shipping Name

ADR/RID: AMINES, LIQUID, CORROSIVE,\nN.O.S. or POLYAMINES, LIQUID, CORROSIVE, N.O.S.
IMDG: AMINES, LIQUID, CORROSIVE,\nN.O.S. or POLYAMINES, LIQUID, CORROSIVE, N.O.S.
IATA: AMINES, LIQUID, CORROSIVE,\nN.O.S. or POLYAMINES, LIQUID, CORROSIVE, N.O.S.

14.3 Transport hazard class(es)

ADR/RID: 8 IMDG: 8 IATA: 8

14.4 Packing group, if applicable

ADR/RID: II IMDG: II IATA: II

14.5 Environmental hazards

ADR/RID: no IMDG: no IATA: no

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name Common names and synonyms CAS number EC number
triethylene glycol triethylene glycol 112-27-6 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Listed.
China Catalog of Hazardous chemicals 2015 Not Listed.
New Zealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.

16.Other information

Information on revision

Creation Date Aug 10, 2017
Revision Date Aug 10, 2017

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%

References

  • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
  • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
  • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
  • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
  • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
  • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
  • ECHA - European Chemicals Agency, website: https://echa.europa.eu/

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.

Precursor and Product
Computational chemical data

Molecular Weight:150.17296 [g/mol]
Molecular Formula:C6H14O4
XLogP3:-1.6
H-Bond Donor:2
H-Bond Acceptor:4
Rotatable Bond Count:7
Exact Mass:150.089209
MonoIsotopic Mass:150.089209
Topological Polar Surface Area:58.9
Heavy Atom Count:10
Formal Charge:0
Complexity:49.7
Isotope Atom Count:0
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:1
Feature 3D Acceptor Count:4
Feature 3D Donor Count:2
Effective Rotor Count:7
Conformer Sampling RMSD:0.6
CID Conformer Count:149