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Home> Hot Product Listed 2   > 2-Naphthol


CAS No.:135-19-3
Molecular Weight:144.17
Molecular Formula:C10H8O (Products with the same molecular formula)
MOL File:135-19-3.mol
Names and Identifiers

Antioxygene BN beta-Naphthol 2-Naphtol azoiccouplingcomponent1 azogendevelopera Beta Naphthol2-Naftol 2-Hydroxynaphthalene2-Naphthol 2-Naftolo Azogen Developer A beta-Monoxynaphthalene B-NAPHTOL

Canonical Smiles
broken white shiny flakes or white powder
Melting Point
Boiling Point
0.00162mmHg at 25°C
Refractive Index
Flash Point
1 g/L (20℃)
Very slightly soluble in water 1 g/L (20 oC)
White, lustrious, bulky leaflets or white powder
Stable. Combustible. Dust may form explosive mixture with air. Incompatible with strong oxidizing agents, phenol.
HS Code
Storage temp
Keep away from heat, sparks, and flame. Keep away from sources of ignition. Do not store in direct sunlight. Keep container closed when not in use. Store in a tightly closed container. Keep from contact with oxidizing materials. Store in a cool, dry, well-ventilated area away from incompatible substances. Keep away from strong bases. Material darkens in color on storage.
Safety and Handling
Hazard Codes
Risk Statements
Safety Statements

Hazard Codes:?HarmfulXn,?DangerousN
Risk Statements: 20/22-50?
R20/22:Harmful by inhalation and if swallowed.?
R50:Very toxic to aquatic organisms.
Safety Statements: 24/25-61?
S24/25:Avoid contact with skin and eyes.?
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
RIDADR: UN 3077 9/PG 3
WGK Germany: 2
RTECS: QL2975000
F: 8
HazardClass: 9
PackingGroup: III
HS Code: 29071590
Poison by ingestion, inhalation, and subcutaneous routes. Mutation data reported. A skin and eye irritant. Combustible when exposed to heat or flame. To fight fire, use CO2, dry chemical. Incompatible with antipyrine, camphor, phenol, ferric salts, menthol, potassium permanganate and other oxidizing materials, urethane.

Skin, Eye, and Respiratory Irritations
/2-Naphthol/ ... can produce ... eye irritation from a 1% solution.
UN 3077 9
Fire Potential
Flammability potential is slight.
Grade: Technical, sublimed, resublimed
Protective Equipment and Clothing
/2-Naphthol/ ... can produce ... eye irritation from a 1% solution.

?2-Naphthol?(CAS NO.135-19-3)?is also named as 2-Hydroxynaphthalene ; 2-Naftol ; 2-Naphthalenol ;?AI3-00081 ; Azogen developer A ; Betanaphthol ; C.I. 37500 ; C.I. Azoic Coupling Component 1 ; C.I. Developer 5 ; Caswell No. 590 ; Developer AMS ; Developer BN ; Developer sodium ; EINECS 205-182-7 ; EPA Pesticide Chemical Code 010301 ; HSDB 6812 ; Isonaphthol ; NAPHTHOL, BETA ; NSC 2044 ; Naphthol B ; UNII-P2Z71CIK5H ; beta-Hydroxynaphthalene ; beta-Monoxynaphthalene .?2-Naphthol (CAS NO.135-19-3) is broken white shiny flakes or white powder. It is?soluble in?ethanol, ether, chloroform, glycerol and alkaline solution, insolublr in water.

Octanol/Water Partition Coefficient
Log Kow = 2.70

Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.

Disposal Methods
SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
Reach Info
This substance has been officially registered by enterprises.
ECHA (EU chemicals Management Agency) published the completed registration file as follows:
Completed registration file:
Registered as ubmitted Total tonnage band  
Registered companies:
Registrant / Supplier details Latest dossier received
Synthesia, a.s. 2012
Cappelle Pigments N.V. 2013
Clariant Plastics & Coatings (Deutschland) GmbH 2015
more >

Download/Modify | Technical supported by For US version, EU version (23 languages) and more, please refer to


According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 10, 2017

Revision Date: Aug 10, 2017


1.1 GHS Product identifier

Product name 2-naphthol

1.2 Other means of identification

Product number -
Other names 2-Naphthalenol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only. Dyes
Uses advised against no data available

1.4 Supplier's details

Company WWW.GuideChem.COM
Address 8F, Block C, No.3 Building, Zijin Plaza, No.701, Gudun Road, Hangzhou, Zhejiang 310030, China
Telephone +86-571-89739798
Fax 86(21)54365166

1.5 Emergency phone number

Emergency phone number +86-571-89739798
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Acute toxicity - Oral, Category 4

Acute toxicity - Inhalation, Category 4

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

2.2 GHS label elements, including precautionary statements

Signal word


Hazard statement(s)

H302 Harmful if swallowed

H332 Harmful if inhaled

H400 Very toxic to aquatic life

Precautionary statement(s)

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P271 Use only outdoors or in a well-ventilated area.

P273 Avoid release to the environment.


P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/\u2026if you feel unwell.

P330 Rinse mouth.

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P312 Call a POISON CENTER/doctor/\u2026if you feel unwell.

P391 Collect spillage.




P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification


3.Composition/information on ingredients

3.1 Substances

Chemical name Common names and synonyms CAS number EC number Concentration
2-naphthol 2-naphthol 135-19-3 none 100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

Fresh air, rest.

In case of skin contact

Rinse and then wash skin with water and soap.

In case of eye contact

First rinse with plenty of water for several minutes (remove contact lenses if easily possible), then refer for medical attention.

If swallowed

Rinse mouth. Give one or two glasses of water to drink. Refer for medical attention .

4.2 Most important symptoms/effects, acute and delayed

no data available

4.3 Indication of immediate medical attention and special treatment needed, if necessary

Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand-valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR as necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Phenols and related compounds/

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Suitable extinguishing media: Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

5.2 Specific hazards arising from the chemical

no data available

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Personal protection: particulate filter respirator adapted to the airborne concentration of the substance. Sweep spilled substance into covered containers. If appropriate, moisten first to prevent dusting. Do NOT let this chemical enter the environment.

6.3 Methods and materials for containment and cleaning up

Accidental Release Measures. Personal precautions, protective equipment and emergency procedures: Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. Environmental precautions: Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided. Methods and materials for containment and cleaning up: Pick up and arrange disposal without creating dust. Sweep up and shovel. Keep in suitable, closed containers for disposal.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Store in an area without drain or sewer access.Conditions for safe storage, including any incompatibilities: Keep container tightly closed in a dry and well-ventilated place. Light sensitive.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state broken white shiny flakes or white powder
Colour White, lustrious, bulky leaflets or white powder. Darkens with age
Odour Faint phenol-like odor
Melting point/ freezing point 220\u00b0C(lit.)
Boiling point or initial boiling point and boiling range 285-286\u00b0C(lit.)
Flammability Combustible.
Lower and upper explosion limit / flammability limit no data available
Flash point 153\u00b0C
Auto-ignition temperature 550\u00b0C
Decomposition temperature no data available
pH no data available
Kinematic viscosity no data available
Solubility In water:1 g/L (20 \u00baC)
Partition coefficient n-octanol/water (log value) log Kow = 2.70
Vapour pressure 10 mm Hg ( 145.5 \u00b0C)
Density and/or relative density 1.28
Relative vapour density 4.97 (vs air)
Particle characteristics no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

Flammability potential is slight.Dust explosion possible if in powder or granular form, mixed with air.

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

Incompatible with antipyrine, camphor, phenol, ferric salts, menthol, potassium permanganate and other oxidizing materials, urethane.

10.6 Hazardous decomposition products

Special hazards arising from the substance or mixture: Carbon oxides.

11.Toxicological information

Acute toxicity

  • Oral: LD50 Rat oral 1960 mg/kg
  • Inhalation: no data available
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available


no data available

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

  • Toxicity to fish: LC50; Species: Micropterus salmoides (Largemouth Bass) eggs and larvae; Conditions: freshwater, flow through, 20.2-23.2\u00b0C, pH 7.41-8.10, hardness 86.8-116.3 mg/L CaCO3, dissolved oxygen 7.1-8.4 mg/L; Concentration: 1000 ug/L for 7 days (95% confidence interval: 290-2270 ug/L)
  • Toxicity to daphnia and other aquatic invertebrates: LC50; Species: Daphnia magna (Water Flea) age 24 hr, juvenile, first instar; Conditions: freshwater, static, 19.5-20.5\u00b0C; Concentration: 3540 ug/L for 48 hr (95% confidence interval: 3170-3950 ug/L)
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available

12.2 Persistence and degradability

AEROBIC: 2-Naphthol, present at 100 mg/L, reached 68.4% of its theoretical BOD in 2 weeks using an activated sludge inoculum at 30 mg/L in the Japanese MITI test(1). In an OECD 301C test, 2-naphthol achieved an observed BOD of 68% after 28 days; the test substance is considered to be readily biodegradable under the conditions of the test(2). 2-Naphthol biodegraded 99.83, 99.98, 99.88, 99.90% after 100, 130, 150, 160 days, respectively, in a biodegradation study using activated sludge(3). Using adapted activated sludge as the inoculum, 2-naphthol degraded 89% based on COD removal at a biodegradation rate of 39.2 mg COD/g-hr(4). The biodegradation potential of 2-naphthol in diluted primary digested sludge was considered to be inhibitory to biodegradation after a lag period of more than 75 days(5). The 5-day BOD of 2-naphthol, present at 5 ppm, was 0.71 g/g or 27.8 of the Theoretical Oxygen Demand(6). In a Chernozem soil at 19\u00b0C, 2-naphthol existed for > 90 days at 500 mg/kg and for 30 days at 5 mg/kg(7). 2-Naphthol is considered to be recalcitrant in Chernozem soils(8).

12.3 Bioaccumulative potential

An estimated BCF of 28 was calculated in fish for 2-naphthol(SRC), using a log Kow of 2.7(1) and a regression-derived equation(2). According to a classification scheme(2), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

12.4 Mobility in soil

The Koc of 2-naphtol is estimated as 390(SRC), using a log Kow of 2.7(1) and a regression-derived equation(2). According to a classification scheme(3), this estimated Koc value suggests that 2-naphthol is expected to have moderate mobility in soil. The pKa of 2-naphthol is 9.51(4), indicating that this compound will exist partially in the anion form in the environment and anions generally do not adsorb more strongly to soils containing organic carbon and clay than their neutral counterparts(5).

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods


The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: UN3077 IMDG: UN3077 IATA: UN3077

14.2 UN Proper Shipping Name


14.3 Transport hazard class(es)


14.4 Packing group, if applicable


14.5 Environmental hazards

ADR/RID: yes IMDG: yes IATA: yes

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name Common names and synonyms CAS number EC number
2-naphthol 2-naphthol 135-19-3 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Listed.
China Catalog of Hazardous chemicals 2015 Not Listed.
New Zealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.

16.Other information

Information on revision

Creation Date Aug 10, 2017
Revision Date Aug 10, 2017

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%


  • IPCS - The International Chemical Safety Cards (ICSC), website:
  • HSDB - Hazardous Substances Data Bank, website:
  • IARC - International Agency for Research on Cancer, website:
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website:
  • CAMEO Chemicals, website:
  • ChemIDplus, website:
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website:
  • Germany GESTIS-database on hazard substance, website:
  • ECHA - European Chemicals Agency, website:

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.

Precursor and Product
Computational chemical data

Molecular Weight:144.16992 [g/mol]
Molecular Formula:C10H8O
H-Bond Donor:1
H-Bond Acceptor:1
Rotatable Bond Count:0
Tautomer Count:3
Exact Mass:144.057515
MonoIsotopic Mass:144.057515
Topological Polar Surface Area:20.2
Heavy Atom Count:11
Formal Charge:0
Isotope Atom Count:0
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:1
Feature 3D Donor Count:1
Feature 3D Ring Count:2
Effective Rotor Count:0
Conformer Sampling RMSD:0.4
CID Conformer Count:1