Related Searches: Erlotinib hydrochloride, Erlotinib, hydrochloride, amino- hydrochloride, acid hydrochloride, View all

Erlotinib hydrochloride(CAS No. 183319-69-9)

Erlotinib hydrochloride C22H24ClN3O4 (cas 183319-69-9) Molecular Structure

183319-69-9 Structure

Identification and Related Records

【Name】
Erlotinib hydrochloride
【Iupac name】
N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine
hydrochloride
【CAS Registry number】
183319-69-9
【Synonyms】
4-Quinazolinamine,N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-, monohydrochloride (9CI)
6,7-Bis(2-methoxyethoxy)-4-(3-ethynylanilino)quinazoline hydrochloride
CP358774
4-Quinazolinamine,N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-, hydrochloride (1:1)
OSI 774
Tarceva
[6,7-Bis(2-methoxyethoxy)quinazolin-4-yl]-(3-ethynylphenyl)amine hydrochloride
Erlotinib HCl
Erlotinib hydrochloride and Intermediate
【Molecular Formula】
C22H24ClN3O4 (Products with the same molecular formula)
【Molecular Weight】
429.9
【Inchi】
InChI=1/C22H23N3O4.ClH/c1-4-16-6-5-7-17(12-16)25-22-18-13-20(28-10-8-26-2)21(29-11-9-27-3)14-19(18)23-15-24-22;/h1,5-7,12-15H,8-11H2,2-3H3,(H,23,24,25);1H
【Canonical SMILES】
COCCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC(=C3)C#C)OCCOC.Cl
【MOL File】
183319-69-9.mol

Chemical and Physical Properties

【Appearance】
White or off-white powder
【Density】
g/cm3
【Melting Point】
223-225°C
【Boiling Point】
553.6 °C at 760 mmHg
【Vapour】
4.52E-12mmHg at 25°C
【Flash Point】
288.6 °C
【Computed Properties】
Molecular Weight:429.89666 [g/mol]
Molecular Formula:C22H24ClN3O4
H-Bond Donor:2
H-Bond Acceptor:4
Rotatable Bond Count:11
Tautomer Count:3
Exact Mass:429.145534
MonoIsotopic Mass:429.145534
Topological Polar Surface Area:74.7
Heavy Atom Count:30
Formal Charge:0
Complexity:525
Isotope Atom Count:0
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:2

Use and Manufacturing

【Usage】

  Erlotinib hydrochloride (CAS NO.183319-69-9) is a drug used to treat non-small cell lung cancer, pancreatic cancer and several other types of cancer. 

Biomedical Effects and Toxicity

【Pharmacological Action】
- Agents that inhibit PROTEIN KINASES.

Supplier Location

Top Suppliers

Diamond member Nanjing Bangnuo Biotechnology Co., Ltd
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-1732-7098554
Diamond member Wuhan Fortuna Chemical Co., Ltd.
Country:ChinaChina
Business Type:Manufacturer
Telephone:0086-27-59207850
Diamond member Hangzhou Dayangchem Co., Ltd.
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-571-88938639
Diamond member Shanghai Do Chemical Co.,Ltd
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-21-33758180
Diamond member Hangzhou Utanpharma biology co,.Ltd
Country:ChinaChina
Business Type:Trading Company
Telephone:86-571-87670983
Diamond member Chengdu Sino-Strong Pharmaceutical Co.,Ltd.
Country:ChinaChina
Business Type:Manufacturer
Telephone:0086-28-82666753
Diamond member Hubei XinRunde Chemical Co., Ltd
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-27-83214668
Diamond member FORT ST BIOLOGICAL TECHNOLOGY LIMITED
Country:ChinaChina
Business Type:Trading Company
Telephone:86-311-13263231263
Diamond member shijiazhuang guizheng trade co.,ltd
Country:ChinaChina
Business Type:Trading Company
Telephone:86-312-18103315327
Diamond member Qingdao happy biological technology co., LTD
Country:ChinaChina
Business Type:Manufacturer
Telephone:86-310-7123336

Quick Search

Cas    Name

Related products

Erlotinib

Erlotinib base;N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)quinazolin-4-amine;4-Quinazolinamine, N-(3-ethynylphenyl)-6,7-bis(2-methoxyethoxy)-,;N-(3-E...

erlotinib

;Tarceva;6,7-BIS-(3-METHOXY-PROPOXY)-QUINAZOLIN-4-YL]-(3-ETHYNYL-PHENYL)-AMINE

7-O-DesMethoxy-7-O-chloroethyl Erlotinib Hydrochloride

7-O-DesMethoxy-7-O-chloroethyl Erlotinib Hydrochloride

6-O-DesMethoxyethyl-6-O-chloroethyl Erlotinib Hydrochloride

6-O-DesMethoxyethyl-6-O-chloroethyl Erlotinib Hydrochloride

Erlotinib iMpurity

Erlotinib iMpurity;Erlotinib iMpurity, 6,7-bis(2-chloroethoxy)

Erlotinib 13C6 HCl

Erlotinib 13C6 HCl

DesMethyl Erlotinib Carboxylate Acid

DesMethyl Erlotinib Carboxylate Acid;2-[[4-[(3-Ethynylphenyl)aMino]-6-(2-Methoxyethoxy)-7-quinazolinyl]oxy];2-[[4-[(3-Ethynylphenyl)aMino]-6-(2-Methox...

Desmethyl Erlotinib Acetate

6-(2-Acetoxy-ethoxy)-4-(3-ethynyl-phenylamino)-7-(2-methoxy-ethoxy)-quinazoline;Desmethyl Erlotinib Acetate;2-[[4-[(3-ethynylphenyl)aMino]-7-(2-Methox...

Erlotinib iMpurity B

Erlotinib iMpurity B;4-QuinazolinaMine, 6-(2-chloroethoxy)-N-(3-ethynylphenyl)-7-(2-Methoxyethoxy)-;Erlotinib iMpurity, 6-(2-Methoxyethoxy)-7-(2-chlor...

OSI-420-d4, Free Base (Desmethyl Erlotinib-d4)

OSI-420-d4, Free Base (Desmethyl Erlotinib-d4);2-[[4-[(3-Ethynylphenyl-d4)aMino]-7-(2-Methoxyethoxy)-6-quinazolinyl]oxy]ethanol

Aureomycin hydrochloride;Chlortetracycline hydrochloride

2-Naphthacenecarboxamide,7-chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-,monohydrochloride (...