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Home> Hot Product Listed T   > Thiabendazole (2-(4-Thiazolyl)-1H-benzimidazole)

Thiabendazole (2-(4-Thiazolyl)-1H-benzimidazole)

CAS No.:148-79-8
Molecular Weight:201.25
Molecular Formula:C10H7N3S (Products with the same molecular formula)
MOL File:148-79-8.mol
light yellow powder
Melting Point
Boiling Point
3.89E-06mmHg at 25°C
Refractive Index
Flash Point
0.005 g/100 mL
0.005 g/100 mL in water
light yellow
Non-volatile @ room temperature; stable in water and in acid and alkaline solution; stable under normal conditions to hydrolysis, light and heat.
Storage temp
Spectral properties
UV Max absorption (methanol): 298 nm (extinction coefficient: 23,330); fluorescence max in acid soln: 370 nm (310 nm excitation)
Intense mass spectral peaks: 201 m/z (100%), 174 m/z (69%), 202 m/z (15%), 175 m/z (9%)
Safety and Handling
Hazard Codes
Risk Statements
Safety Statements

Moderately toxic by ingestion. An experimental teratogen. A questionable carcinogen. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of SOx and NOx.
Safety Information of Thiabendazole (CAS NO.148-79-8):
Hazard Codes:DangerousN,IrritantXi
Risk Statements:
36/37/38:? Irritating to eyes, respiratory system and skin?
50/53:? Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment?
Safety Statements:
26:? In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
36:? Wear suitable protective clothing?
60:? This material and/or its container must be disposed of as hazardous waste?
61:? Avoid release to the environment. Refer to special instructions safety data sheet?
RIDADR: UN 3077 9/PG 3
WGK Germany: 2
RTECS: DE0700000
HazardClass: 9
PackingGroup: III

Skin, Eye, and Respiratory Irritations
/Thiabendazole/ is neither irritating to the eyes or skin nor is a dermal sensitizer.
Cleanup Methods
SRP: Wastewater from contaminant suppression, cleaning of protective clothing/equipment, or contaminated sites should be contained and evaluated for subject chemical or decomposition product concentrations. Concentrations shall be lower than applicable environmental discharge or disposal criteria. Alternatively, pretreatment and/or discharge to a POTW is acceptable only after review by the governing authority. Due consideration shall be given to remediation worker exposure (inhalation, dermal and ingestion) as well as fate during treatment, transfer and disposal. If it is not practicable to manage the chemical in this fashion, it must meet Hazardous Material Criteria for disposal.
UN 3077
USEPA/OPP Pesticide Code 060101; Trade Names: Arbotect; Mertect; TBZ; Apl-luster; Bioguard; Bovizole; Eprofil; Equizole; Lombristop; Mertect 160; Metasol TK 100; Mintesol; Mycozol; MK 360; Nemapan; Omnizole; Polival; Tebuzate; Tecto; Thibenzole 200; Thiprazole; Top Form Wormer; Agrosol, component of (with 081301); Agrosol T, component of (with 079801).
The following thiabendazole formulation types are registered: a ready-to-use, dusts, flowable concentrates, emulsifiable concentrates, wettable powders, granules, and water dispersable granules.
Oral: Suspension: 500 mg/5 mL Mintezol (Merck); Tablets, chewable: 500 mg Mintezol (scored) (Merck).
Formulations include wettable powders (400,000, and 900 g active ingredient/kg), flowable suspensions (450 g active ingredient/l), and fumigation tablets (7 g active ingredient).
Combinations: Captan T (captan + thiabendazole), RTU Flowable Fungicide (thiram + thiabendazole), Rival (captan + PCNB + thiabendazole)
Mertect (R) 340-F Fungicide; Active ingredient 42.30% Thiabendazole
Arbotect 20-S Fungicide; Active ingredient 26.60% Thiabendazole
Thiabendazole Technical MF; Active ingredient 99.50% Thiabendazole
Tecto MP 340; Active ingredient 42.30% Thiabendazole
TEcto-Shield MP 100; Active ingredient 99.50% Thiabendazole
Azotech; Active ingredients 19.50% Thiabendazole and 15.00% Azoxystrobin
Sporgard; Active ingredients 19.04% Thiabendazole, 1.92% Fludioxonil, and 19.04% Azoxystrobin
Gustafson LSP Flowable Fungicide; Active ingredient 30.00% Thiabendazole
Decco Salt No. 19; Active ingredient 99.50% Thiabendazole
Freshgard 598; Active ingredient 99.50% Thiabendazole
Ultra-Fresh PF-1 Fungicide; Active ingredient 25.00% Thiabendazole
Ultra-Fresh DW-30; Active ingredients 15.00% Thiabendazole and 15.00% Zinc 2-pyridinethiol-1-oxide
Metasol TK-100 Dispersion W; Active ingredient 50.00% Thiabendazole
Metasol TK-100; Active ingredient 99.50% Thiabendazole
Thiabendazole Dispersion W; Active ingredient 50.00% Thiabendazole
Metasol TK-25 AD; Active ingredient 25.00% Thiabendazole
Metasol TK-50 AD; Active ingredient 50.00% Thiabendazole
Metasol TK-100 Technical; Active ingredient 99.50% Thiabendazole
Preventol A17-D; Active ingredients 25.50% Thiabendazole and 4.2% Octhilinone
Irgaguard F3000; Active ingredient 99.50% Thiabendazole
Chem-Tek 100; Active ingredient 99.50% Thiabendazole
Stay-Clean I/E; Active ingredient 50.00% Thiabendazole
Super Mildex; Active ingredient 50.00% Thiabendazole
Shield-Brite TBZ; Active ingredient 99.50% Thiabendazole
Krud Kutter MC-2; Active ingredient 50.00% Thiabendazole
Exposure Standards and Regulations
Thiabendazole ... is used as follows: (3) Goats. In a bolus. (i) Amount. 3 grams per 100 pounds of body weight. (ii) Indications for use. Control of severe infections of gastrointestinal roundworms (genera Trichostrongylus spp., Haemonchus spp., Ostertagia spp., Cooperia spp., Nematodirus spp., Bunostomum spp., Strongyloides spp., Chabertia spp., and Oesophagostomum spp.). (iii) Limitations. As a single oral dose; do not treat animals within 30 days of slaughter; milk taken from treated animals within 96 hours (8 milkings) after the latest treatment must not be used for food; treatment should be repeated in 2 to 3 weeks.
Reactivities and Incompatibilities
Incompatible with a number of pesticides including copper-containing fungicides, & highly alkaline materials.
Other Preventative Measures
SRP: Contaminated protective clothing should be segregated in such a manner so that there is no direct personal contact by personnel who handle, dispose, or clean the clothing. Quality assurance to ascertain the completeness of the cleaning procedures should be implemented before the decontaminated protective clothing is returned for reuse by the workers. Contaminated clothing should not be taken home at end of shift, but should remain at employee's place of work for cleaning.
SRP: The scientific literature for the use of contact lenses in industry is conflicting. The benefit or detrimental effects of wearing contact lenses depend not only upon the substance, but also on factors including the form of the substance, characteristics and duration of the exposure, the uses of other eye protection equipment, and the hygiene of the lenses. However, there may be individual substances whose irritating or corrosive properties are such that the wearing of contact lenses would be harmful to the eye. In those specific cases, contact lenses should not be worn. In any event, the usual eye protection equipment should be worn even when contact lenses are in place.
Users should wash hands before eating, drinking, chewing gum, tobacco, or using the toilet.
Users should remove clothing/PPE immediately if pesticides get inside. Then wash thoroughly and put on clean clothing.
Users should remove PPE immediately after handling this product. As soon as possible, wash thoroughly and change into clean clothing.
Do not apply directly to water. Do not contaminate water by cleaning of equipment or disposal of waste.
Do not enter or allow worker entry into treated areas during the restricted entry interval (REI) of 12 hours.
Follow manufacturer's instructions for cleaning/maintaining PPE. If no such instructions for washables exist, use detergent and hot water. Keep and wash PPE separately from other laundry.
Protective Equipment and Clothing
/Thiabendazole/ is neither irritating to the eyes or skin nor is a dermal sensitizer.

?Thiabendazole (CAS NO.148-79-8), its Synonyms are 1H-Benzimidazole, 2-(4-thiazolyl)- ; 2-(4-Thiazolyl)benzimidazole ; 2-(1,3-Thiazol-4-yl)benzimidazole ; 2-(4-Thiazolyl)-1H-benzimidazole ; 2-Thiazole-4-ylbenzimidazole ; 4-(2-Benzimidazolyl)thiazole ; Benzimidazole, 2-(4-thiazolyl)- ; Biogard ; Bioguard ; Helmindrax octelmin ; Hokustar HP ; Lombristop ; Thiaben ; Thiabendazol .

Octanol/Water Partition Coefficient
log Kow = 2.47 [Nielsen LS et al; Acta Pharm Nord 4: 43-9 (1992)] PubMed Abstract

EPA Genetic Toxicology Program. Reported in EPA TSCA Inventory.

Disposal Methods
SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.
If reuse is not possible thiabendazole should be incinerated in a unit equipped with an effluent gas scrubber to remove SO2 /sulfur dioxide/. Incineration temp above 1000 deg C about 1-2 sec. Recommendable method: Incineration.
Do not discharge effluent containing this product into lakes, streams, ponds, estuaries oceans or other waters unless in accordance with the requirements of a National Pollutant Discharge Elimination System (NPDES) permit and the permitting authority has been notified in writing prior to discharge.
Reach Info

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According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017


1.1 GHS Product identifier

Product name thiabendazole

1.2 Other means of identification

Product number -
Other names tiabendazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

Company WWW.GuideChem.COM
Address 8F, Block C, No.3 Building, Zijin Plaza, No.701, Gudun Road, Hangzhou, Zhejiang 310030, China
Telephone +86-571-89739798
Fax 86(21)54365166

1.5 Emergency phone number

Emergency phone number +86-571-89739798
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

2.2 GHS label elements, including precautionary statements

Signal word


Hazard statement(s)

H410 Very toxic to aquatic life with long lasting effects

Precautionary statement(s)

P273 Avoid release to the environment.


P391 Collect spillage.




P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification


3.Composition/information on ingredients

3.1 Substances

Chemical name Common names and synonyms CAS number EC number Concentration
thiabendazole thiabendazole 148-79-8 none 100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms/effects, acute and delayed

no data available

4.3 Indication of immediate medical attention and special treatment needed, if necessary

no data available

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

5.2 Specific hazards arising from the chemical

no data available

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.

6.3 Methods and materials for containment and cleaning up

Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state light yellow powder
Colour no data available
Odour no data available
Melting point/ freezing point 298-301\u00baC
Boiling point or initial boiling point and boiling range 446\u00baC at 760mmHg
Flammability no data available
Lower and upper explosion limit / flammability limit no data available
Flash point 226.2\u00baC
Auto-ignition temperature no data available
Decomposition temperature no data available
pH no data available
Kinematic viscosity no data available
Solubility no data available
Partition coefficient n-octanol/water (log value) no data available
Vapour pressure 3.89E-06mmHg at 25\u00b0C
Density and/or relative density 1.406g/cm3
Relative vapour density no data available
Particle characteristics no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

no data available

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

no data available

10.6 Hazardous decomposition products

no data available

11.Toxicological information

Acute toxicity

  • Oral: no data available
  • Inhalation: no data available
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available


no data available

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

  • Toxicity to fish: no data available
  • Toxicity to daphnia and other aquatic invertebrates: no data available
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available

12.2 Persistence and degradability

no data available

12.3 Bioaccumulative potential

no data available

12.4 Mobility in soil

no data available

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods


The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: UN3077 IMDG: UN3077 IATA: UN3077

14.2 UN Proper Shipping Name


14.3 Transport hazard class(es)


14.4 Packing group, if applicable


14.5 Environmental hazards

ADR/RID: yes IMDG: yes IATA: yes

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name Common names and synonyms CAS number EC number
thiabendazole thiabendazole 148-79-8 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Listed.
China Catalog of Hazardous chemicals 2015 Not Listed.
New Zealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.

16.Other information

Information on revision

Creation Date Aug 12, 2017
Revision Date Aug 12, 2017

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%


  • IPCS - The International Chemical Safety Cards (ICSC), website:
  • HSDB - Hazardous Substances Data Bank, website:
  • IARC - International Agency for Research on Cancer, website:
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website:
  • CAMEO Chemicals, website:
  • ChemIDplus, website:
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website:
  • Germany GESTIS-database on hazard substance, website:
  • ECHA - European Chemicals Agency, website:

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.

Precursor and Product
Computational chemical data

Molecular Weight:201.24768 [g/mol]
Molecular Formula:C10H7N3S
H-Bond Donor:1
H-Bond Acceptor:1
Rotatable Bond Count:1
Exact Mass:201.036068
MonoIsotopic Mass:201.036068
Topological Polar Surface Area:69.8
Heavy Atom Count:14
Formal Charge:0
Isotope Atom Count:0
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:1
Feature 3D Acceptor Count:1
Feature 3D Donor Count:1
Feature 3D Cation Count:1
Feature 3D Ring Count:3
Effective Rotor Count:1
Conformer Sampling RMSD:0.4
CID Conformer Count:2