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Home> Hot Product Listed P   > PENTAZOCINE LACTATE
84541-38-8 structure

PENTAZOCINE LACTATE

CAS No.:84541-38-8
Molecular Weight:501.64
Molecular Formula:C13H16O3 (isomer)
Names and Identifiers
Synonyms

2-hydroxypropanoic acid - (2R,6R,11R)-6,11-dimethyl-3-(3-methylbut-2-en-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol (1:1) 2-hydroxypropanoic acid - (2S,6S)-6,11-dimethyl-3-(3-methylbut-2-en-1-yl)-1,2,3,4,5,6-hexahydro-2,6-methano-3-benzazocin-8-ol (1:1) CHEMBL1200327 D02111 lactic acid, compound with (2alpha,6alpha,11R*)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methylbut-2-enyl)-2,6-methano-3-benzocin-8-ol (1:1) pentazocine lactate (usp) SCHEMBL42094 talwin (tn)

Properties
Melting Point
75-85°C
Flash Point
°C
Solubility
1 G IN GREATER THAN 1000 ML WATER, 11 ML ALCOHOL, 2 ML CHLOROFORM, 42 ML ETHER
SOL IN ACETONE; SPARINGLY SOL IN ETHYL ACETATE
Color/Form
WHITE TO VERY PALE TAN CRYSTALLINE POWDER
Crystals from methanol and water
Spectral properties
Intense mass spectral peaks: 70 m/z, 110 m/z, 217 m/z, 285 m/z
Safety and Handling
Safety

A poison by intraperitoneal route. Human systemic effects. A human skin irritant. When heated to decomposition it emits toxic vapors of NOx.

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
man TDLo parenteral 16mg/kg/3W-I (16mg/kg) MUSCULOSKELETAL: OTHER CHANGES Journal of Rheumatology. Vol. 13, Pg. 210, 1986.
mouse LD50 intraperitoneal 103mg/kg (103mg/kg)   Journal of Pharmacy and Pharmacology. Vol. 23, Pg. 882, 1971.
women TDLo subcutaneous 2mg/kg (2mg/kg) SKIN AND APPENDAGES (SKIN): "DERMATITIS, OTHER: AFTER SYSTEMIC EXPOSURE" Archives of Dermatology. Vol. 123, Pg. 297, 1987.

Formulations/Preparations
Pentazocine is commercially available as the hydrochloride salt ... & as the lactate salt ...
Pentazocine lactate (Talwin) is avail as soln for injection, each ml of which contains the equiv of 30 mg of the base. In an effort to reduce the use of tablets as a source of injectable pentazocine, tablets for oral use now contain pentazocine hydrochloride (equiv to 50 mg of the base) & 0.5 mg of naloxone (Talwin NX). ... Tablets containing mixt of pentazocine with aspirin or acetaminophen are also avail.
Fortral (United Kingdom); Algopent (Italy); Fortalgesic (Sweden, Switerland). /Pentazocine hydrochloride/
Exposure Standards and Regulations
Schedules of controlled substances are established by section 202 of the Controlled Substances Act (21 U.S.C. 812). Schedule IV includes pentazocine, DEA Code #9709; Drug class: Other substances.
Horses - For symptomatic relief of pain due to colic. Administer intravenously or intramuscularly. Intravenous injections are given slowly in the jugular vein. ... Not for use in horses intended for food. Federal law restricts this drug to use by or on the order of a licensed veterinarian. /Pentazocine lactate injection/
Dogs - For amelioration of pain accompanying postoperative recovery, fracture, trauma, and spinal disorders. Administer intramuscularly only. Federal law restricts this drug to use by or on the order of a licensed veterinarian. /Pentazocine lactate injection/
Specification

 Pentazocine lactate , its CAS NO. is 17146-95-1, the synonyms are  (2R*,6R*,11R*)-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methano-3-benzazocin-8-ol lactate (salt) ; 2-Hydroxypropanoic acid compd. with (2alpha,6alpha,11R*)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methanol-3-benzocin-8-ol (1:1) ; Liticon ; Pentalgine ; Talwin ; UNII-1P2XIB510O ; 2,6-Methano-3-benzazocin-8-ol, 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-, (2alpha,6alpha,11R*)-, compd. with 2-hydroxypropanoic acid (1:1) ; Lactic acid, compd. with 1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methano-3-benzazocin-8-ol (1:1) ; Lactic acid, compound with (2alpha,6alpha,11R*)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methylbut-2-enyl)-2,6-methano-3-benzocin-8-ol (1:1) ; Propanoic acid, 2-hydroxy-, compd. with (2alpha,6alpha,11R*)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-3-(3-methyl-2-butenyl)-2,6-methanol-3-benzocin-8-ol (1:1) .

Octanol/Water Partition Coefficient
log Kow= 3.31
Disposal Methods
SRP: At the time of review, criteria for land treatment or burial (sanitary landfill) disposal practices are subject to significant revision. Prior to implementing land disposal of waste residue (including waste sludge), consult with environmental regulatory agencies for guidance on acceptable disposal practices.
MSDS

2.Hazard identification

2.1 Classification of the substance or mixture

no data available

2.2 GHS label elements, including precautionary statements

Pictogram(s) no data available
Signal word

no data available

Hazard statement(s)

no data available

Precautionary statement(s)
Prevention

no data available

Response

no data available

Storage

no data available

Disposal

no data available

2.3 Other hazards which do not result in classification

no data available

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