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Home> Encyclopedia > Hot Product Listed S   > Salicylic acid
69-72-7 structure

Salicylic acid

Iupac Name:2-hydroxybenzoic acid
CAS No.:69-72-7
EINECS(EC#): 200-712-3
Molecular Weight:138.12
Molecular Formula:C7H6O3 (isomer)
Names and Identifiers
Synonyms

197900-EP2269975A2 197900-EP2269997A2 197900-EP2275415A2 29656-58-4 2-Carboxyphenol 2-hydroxy benzoic acid 2-hydroxy(1-14c)benzoic acid 2-Hydroxybenzenecarboxylate 2-Hydroxybenzenecarboxylic acid 2-Hydroxybenzoate, I 2-Hydroxybenzoic acid 2-hydroxy-benzoic acid 2-Hydroxybenzoic Acid, Natural 2-Hydroxybenzoic Acid/Salicylic Acid 3253-EP2269610A2 3253-EP2269988A2 3253-EP2270002A1 3253-EP2270006A1 3253-EP2270008A1 3253-EP2270011A1 3253-EP2270113A1 3253-EP2272935A1 3253-EP2275401A1 3253-EP2275413A1 3253-EP2275420A1 3253-EP2277867A2 3253-EP2280003A2 3253-EP2280008A2 3253-EP2280010A2 3253-EP2281563A1 3253-EP2281816A1 3253-EP2284146A2 3253-EP2284147A2 3253-EP2284160A1 3253-EP2284178A2 3253-EP2284179A2 3253-EP2287156A1 3253-EP2289510A1 3253-EP2289883A1 3253-EP2289890A1 3253-EP2292592A1 3253-EP2292597A1 3253-EP2292617A1 3253-EP2295053A1 3253-EP2295401A2 3253-EP2295416A2 3253-EP2295424A1 3253-EP2295433A2 3253-EP2298734A2 3253-EP2298735A1 3253-EP2298748A2 3253-EP2298757A2 3253-EP2298758A1 3253-EP2298759A1 3253-EP2298764A1 3253-EP2298765A1 3253-EP2301931A1 3253-EP2301937A1 3253-EP2301940A1 3253-EP2305243A1 3253-EP2305248A1 3253-EP2305257A1 3253-EP2305646A1 3253-EP2305651A1 3253-EP2305655A2 3253-EP2305662A1 3253-EP2305663A1 3253-EP2305664A1 3253-EP2305675A1 3253-EP2308851A1 3253-EP2308854A1 3253-EP2308873A1 3253-EP2308875A1 3253-EP2311807A1 3253-EP2311809A1 3253-EP2311810A1 3253-EP2311814A1 3253-EP2311831A1 3253-EP2311842A2 3253-EP2314574A1 3253-EP2314588A1 3253-EP2316457A1 3253-EP2316458A1 3253-EP2316459A1 3253-EP2316825A1 3253-EP2316826A1 3253-EP2316827A1 3253-EP2316828A1 3253-EP2316836A1 3253-EP2372017A1 3253-EP2380874A2 44642-EP2281819A1 44642-EP2292619A1 44642-EP2305659A1 44642-EP2311818A1 69-72-7 8052-31-1 AB00489876_15 AB1002436 AC1L190M AC1Q1HCK AC1Q72IF Acido o-idrossibenzoico Acido o-idrossibenzoico [Italian] Acido salicilico Acido salicilico [Italian] Acidum salicylicum ACMC-1AZIK Advanced pain relief callus removers Advanced pain relief corn removers AI3-02407 AJ-08047 AK112186 AKOS000118979 Akurza Cream Akurza Lotion Alpha/Beta Hydroxy Acids (Glycolic Acid, Salicylic Acid) ALPHA/BETA HYDROXY ACIDS (SALICYLIC ACID) (SEE ALPHA/BETA HYDROXY ACIDS) AN-41922 Anti-blemish ANW-43703 ARONIS27188 ATA fraction 10, ammonium salt Bazuka Extra Strength Gel BC221968 BCP09067 BDBM26193 Benzoic acid, 2-hydroxy- Benzoic acid, 2-hydroxy- (9CI) Benzoic acid, hydroxy- Benzoic acid, o-hydroxy- BENZOIC ACID,2-HYDROXY SALICYLIC ACID BIDD:ER0602 bmse000252 BP-12826 BRN 0774890 C00805 CAS-69-72-7 Caswell No. 731 CCG-212792 CCRIS 6714 Certified Reference Material CHEBI:16914 CHEMBL424 Clear away wart remover CMC_13852 component of Fostex medicated bar and cream (Salt/Mix) component of Keralyt (Salt/Mix) component of Solarcaine first aid spray (Salt/Mix) component of Tinver (Salt/Mix) CTK1A3418 D00097 DB00936 DHS Sal Shampoo DivK1c_000301 Domerine Domerine (Salt/Mix) Dr. Scholl's callus removers Dr. Scholl's corn removers Dr. Scholl's wart remover kit DSSTox_CID_6368 DSSTox_GSID_26368 DSSTox_RID_78106 DTXSID7026368 Duofil wart remover Duofilm Duofilm (Salt/Mix) Duofilm Wart Remover Duoplant DuoPlant Gel Durasal E9A559BE-383B-4F83-BC02-3031D03D558A EC 200-712-3 EINECS 200-712-3 EPA Pesticide Chemical Code 076602 Epitope ID:124929 F2191-0216 FEMA3985 Fostex (Salt/Mix) Freezone FT-0645123 GTPL4306 HMS2233A10 HMS3373M19 HSDB 672 HY-B0167 Hydrisalic Gel hydroxy-benzoic acid I04-0192 IDI1_000301 InChI=1/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10 Ionil Ionil plus Ionil-Plus J-509667 K 537 KBio1_000301 KBio2_001428 KBio2_003996 KBio2_006564 KBioSS_001428 Keralyt KS-00000KPH KS-000048O6 KSC-11-207-4 KSC203I1R KUC106694N Kyselina 2-hydroxybenzoova Kyselina 2-hydroxybenzoova [Czech] Kyselina salicylova Kyselina salicylova [Czech] LS-2169 MCULE-8407868694 Medicinal grade salicylic acid Medicinal Salicylic Acid Mediplast pads MFCD00002439 MLS000069653 Natural Salicylic Acid NCGC00159447-02 NCGC00159447-04 NCGC00159447-05 NCGC00159447-06 NCGC00257065-01 NCGC00259022-01 NE10196 NINDS_000301 NSC 180 NSC180 NSC-180 NSC629474 O414PZ4LPZ o-Carboxyphenol Occlusal o-hydroxy benzoic acid o-hydroxybenzoic acid Opera_ID_582 Oprea1_040343 Orthohydroxybenzoic acid ortho-hydroxybenzoic acid ortho-salicylic acid P&S Shampoo Pernox (Salt/Mix) phenol derivative, 7 Phenol-2-carboxylate Phenol-2-carboxylic acid Propa pH Peel-Off Acne Mask Psoriacid-S-stift Retarder SAX Retarder SAX (Salt/Mix) Retarder W RP20408 RTR-032850 Rutranex s4539 Salex Cream Salex Lotion Salicyclic acid salicylate salicylic Salicylic acid & Sulfur Soap Salicylic acid & Sulfur Soap (Salt/Mix) Salicylic acid (6CI,8CI) Salicylic acid (JP17/USP) Salicylic Acid (Pharm) SALICYLIC ACID (SEE ALSO ALPHA HYDROXY ACIDS) Salicylic Acid (Sublimed) Salicylic acid (TN) Salicylic acid [USAN:JAN] Salicylic acid [USP:JAN] Salicylic Acid 1.0 mg/ml in Acetonitrile Salicylic acid ACS grade Salicylic acid collodion Salicylic acid soap Salicylic Acid(Tech) Salicylic acid, >=99%, FG Salicylic acid, 1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material Salicylic acid, 99+% Salicylic acid, 99+%, ACS reagent SALICYLIC ACID, ACS Salicylic acid, ACS reagent, >=99.0% Salicylic acid, BioXtra, >=99.0% Salicylic acid, British Pharmacopoeia (BP) Reference Standard Salicylic acid, certified reference material, TraceCERT(R) Salicylic acid, European Pharmacopoeia (EP) Reference Standard Salicylic acid, LR, >=99% Salicylic acid, meets analytical specification of Ph. Eur., BP, USP, 99.5-100.5% (calc. to the dried substance) Salicylic acid, p.a., 99.0% Salicylic acid, Pharmaceutical Secondary Standard Salicylic acid, plant cell culture tested Salicylic acid, puriss. p.a., >=99.0% (T) Salicylic acid, ReagentPlus(R), >=99% Salicylic acid, SAJ first grade, >=99.0% Salicylic acid, tech Salicylic acid, tech. Salicylic acid, tested according to Ph.Eur. Salicylic acid, United States Pharmacopeia (USP) Reference Standard Salicylic acid, Vetec(TM) reagent grade, 98% Salicylic Acid,(S) Salicylic acid,medicinal salicylic-acid salicylicum acidum Saligel Salonil SBB052826 SBI-0051510.P003 SC-18305 SCHEMBL1967 Sebucare Sebucare (Salt/Mix) Sebulex Sebulex (Salt/Mix) SGCUT00012 SMP2_000145 SMR000059163 Spectrum_000948 ST2416966 ST51046715 STK258681 Stri-Dex Sublimed Salicylic Acid Sulfasalazine Impurity H to_000004 Tox21_113453 Tox21_201471 Tox21_303109 TR-032850 Trans-Ver-Sal TS-03583 UNII-I3P9R8317T component YGSDEFSMJLZEOE-UHFFFAOYSA-N UNII-O414PZ4LPZ UPCMLD-DP126 UPCMLD-DP126:001 Verrugon WLN: QVR BQ YGSDEFSMJLZEOE-UHFFFAOYSA-N ZINC1554

Inchi
InChI=1/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10)
InChkey
YGSDEFSMJLZEOE-UHFFFAOYSA-N
Canonical Smiles
C1=CC=C(C(=C1)C(=O)O)O
Isomers Smiles
C1=CC=C(C(=C1)C(=O)O)O
Properties
Appearance
white to off-white crystalline powder
Density
1.44
Melting Point
158-161℃
Boiling Point
211℃ (20 mmHg)
Vapour
8.20e-05 mmHg
Refractive Index
1,565
Flash Point
157℃
Solubility
Slight SOLVENT soluble in alcohol, ether, boiling water, sparingly soluble in chloroform
Stability
Stable. Substances to be avoided include oxidizing agents, strong bases, iodine, fluorine. Combustible. Sensitive to light.
HS Code
29182100
Storage temp
Store at RT.
Safety and Handling
Hazard Codes
Xn
Risk Statements
R22;R36/37/38;R41
Safety Statements
S26;S37/39
Safety

Hazard Codes:?Xn
Risk Statements:? 22-41-36/37/38
22:? Harmful if swallowed?
41:? Risk of serious damage to eyes?
36/37/38:? Irritating to eyes, respiratory system and skin
Safety Statements:? 26-39-37/39-36
26:? In case of contact with eyes, rinse immediately with plenty of water and seek medical advice?
39:? Wear eye/face protection?
37/39:? Wear suitable gloves and eye/face protection?
36:? Wear suitable protective clothing
WGK Germany:? 1
HS Code: ?29182100

Toxicity

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
cat LD50 oral 400mg/kg (400mg/kg) ? "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 148, 1959.
mammal (species unspecified) LC50 inhalation > 300mg/m3 (300mg/m3) ? Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 57(7-8), Pg. 31, 1992.
man TDLo skin 57mg/kg (57mg/kg) SENSE ORGANS AND SPECIAL SENSES: TINNITUS: EAR JAMA, Journal of the American Medical Association. Vol. 244, Pg. 660, 1980.
mouse LD50 intraperitoneal 300mg/kg (300mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION
Gendai no Rinsho. Vol. 3, Pg. 675, 1969.
mouse LD50 intravenous 184mg/kg (184mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Yakugaku Zasshi. Journal of Pharmacy. Vol. 91, Pg. 550, 1971.
mouse LD50 oral 480mg/kg (480mg/kg) ? "Handbook of Toxicology," 4 vols., Philadelphia, W.B. Saunders Co., 1956-59Vol. 5, Pg. 148, 1959.
mouse LD60 subcutaneous 520mg/kg (520mg/kg) CARDIAC: CHANGE IN RATE

BEHAVIORAL: MUSCLE WEAKNESS
Archives Internationales de Pharmacodynamie et de Therapie. Vol. 38, Pg. 9, 1930.
rabbit LD50 oral 1300mg/kg (1300mg/kg) ? Drugs in Japan Vol. 6, Pg. 291, 1982.
rabbit LD50 skin > 10gm/kg (10000mg/kg) ? BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 21-3/1971,
rabbit LDLo subcutaneous 6gm/kg (6000mg/kg) ? "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1392, 1935.
rat LC50 inhalation > 900mg/m3/1H (900mg/m3) ? BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 21-3/1971,
rat LD50 intraperitoneal 157mg/kg (157mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: TREMOR
Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 57(7-8), Pg. 31, 1992.
rat LD50 oral 891mg/kg (891mg/kg) BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY)

BEHAVIORAL: MUSCLE WEAKNESS
BIOFAX Industrial Bio-Test Laboratories, Inc., Data Sheets. Vol. 21-3/1971,
rat LD50 skin > 2gm/kg (2000mg/kg) LIVER: OTHER CHANGES

SKIN AND APPENDAGES (SKIN): HAIR: OTHER
Acute Toxicity Data. Journal of the American College of Toxicology, Part B. Vol. 15(Suppl,
women TDLo skin 111mg/kg/10D- (111mg/kg) SENSE ORGANS AND SPECIAL SENSES: CHANGE IN ACUITY: EAR

CARDIAC: PULSE RATE INCREASE WITHOUT FALL IN BP
Postgraduate Medical Journal. Vol. 70, Pg. 146, 1994.

PackingGroup
Z01
Transport
25kgs
Specification

The chief derivative of Salicylic Acid (CAS NO.69-72-7), which is used as a drug, is the methyl acetyl ester, known as aspirin.

MSDS

2.Hazard identification

2.1 Classification of the substance or mixture

Acute toxicity - Oral, Category 4

Serious eye damage, Category 1

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word

Danger

Hazard statement(s)

H302 Harmful if swallowed

H318 Causes serious eye damage

Precautionary statement(s)
Prevention

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

Response

P301+P312 IF SWALLOWED: Call a POISON CENTER/doctor/\u2026if you feel unwell.

P330 Rinse mouth.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P310 Immediately call a POISON CENTER/doctor/\u2026

Storage

none

Disposal

P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

Precursor and Product
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