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Home> Hot Product Listed T   > Tetramethyl ammonium chloride
75-57-0 structure

Tetramethyl ammonium chloride

CAS No.:75-57-0
EINECS(EC#): 200-880-8
Molecular Weight:74.14478
Molecular Formula:C4H12N+ (isomer)
Names and Identifiers
Synonyms

Ammonium,tetramethyl-, chloride (8CI) Methanaminium, N,N,N-trimethyl-, chloride (9CI) Tetramethylammonium chloride (6CI) Tetramine chloride

Inchi
InChI=1/C4H12N.ClH/c1-5(2,3)4;/h1-4H3;1H/q+1;/p-1
InChkey
OKIZCWYLBDKLSU-UHFFFAOYSA-M
Canonical Smiles
C[N+](C)(C)C
Properties
Appearance
white crystals
Density
1,17
Melting Point
420℃
Solubility
>60 g/100 mL (20 °C ) in water
Stability
Stable. Incompatible with strong oxidizing agents, water. Hygroscopic.
HS Code
29239000
Storage temp
Store at RT.
Safety and Handling
Hazard Codes
T
Risk Statements
R25;R36/37/38
Safety Statements
S26;S28;S37/39;S45
HazardClass
6.1
Safety

Poison by ingestion, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx, NH3, and Cl?. See also CHLORIDES.
Hazard Codes:?T,Xn
Risk Statements: 21-25-36/37/38-20/21/22
R21:Harmful in contact with skin.?
R25 :Toxic if swallowed.?
R36/37/38:Irritating to eyes, respiratory system and skin.?
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed.
Safety Statements: 26-36/37-45-37/39-28A-28-36
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.?
S36/37:Wear suitable protective clothing and gloves.?
S45:In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)?
S37/39:Wear suitable gloves and eye/face protection.?
S28:After contact with skin, wash immediately with plenty of soap-suds.?
S36:Wear suitable protective clothing.
RIDADR: UN 2811 6.1/PG 2
WGK Germany: 1
RTECS: BS7700000
F: 3-10
HazardClass: 6.1
PackingGroup: II
HS Code: 29239000

Toxicity
1. ???

orl-mus LDLo:125?mg/kg

??? JPMSAE ?? Journal of Pharmaceutical Sciences. 69 (1980),327.
2. ???

ipr-mus LD50:25?mg/kg

??? NTIS** ?? National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) AD414-344 .
3. ???

scu-mus LD50:40?mg/kg

??? NTIS** ?? National Technical Information Service. (Springfield, VA 22161) (Formerly U.S. Clearinghouse for Scientific and Technical Information) ORNL-5576 .
4. ???

scu-rbt LDLo:6?mg/kg

??? AIPTAK ?? Archives Internationales de Pharmacodynamie et de Therapie. 7 (1900),183.
5. ???

scu-frg LDLo:2?mg/kg

??? SAPHAO ?? Skandinavisches Archiv fuer Physiologic. 10 (1900),201.
PackingGroup
II
Sensitive
Hygroscopic
Transport
UN 2811
Specification

? Tetramethyl ammonium chloride , with CAS number of 75-57-0, can be called methanaminium, N,N,N-trimethyl-, chloride (1:1) ; N,N,N-Trimethylmethanaminium chloride ; TMAC . It is a?white crystal. Tetramethyl ammonium chloride (CAS NO.75-57-0) is used as a phase transfer catalyst for anionic reactants. In small concentrations, also has been shown to enhance yield 5-10 fold at 3M by stabilizing the AT base pairs. Besidea used with polymerase chain reactions to increase yield and specificity.

Report

Reported in EPA TSCA Inventory.

Reach Info
This substance has been officially registered by enterprises.
ECHA (EU chemicals Management Agency) published the completed registration file as follows:
Completed registration file:
Registered as ubmitted Total tonnage band  
FULL JOINT 100_1000 view >
INTERMEDIATE JOINT INTERMEDIATE_USE_ONLY view >
Registered companies:
Registrant / Supplier details Latest dossier received
Sachem Europe BV 2016
SACHEM Europe BV (OR SAM) 2013
OLON Spa 2017
more >
MSDS

2.Hazard identification

2.1 Classification of the substance or mixture

Acute toxicity - Oral, Category 2

Acute toxicity - Dermal, Category 3

Skin irritation, Category 2

Specific target organ toxicity \u2013 single exposure, Category 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 2

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word

Danger

Hazard statement(s)

H300 Fatal if swallowed

H311 Toxic in contact with skin

H315 Causes skin irritation

H370 Causes damage to organs

H411 Toxic to aquatic life with long lasting effects

Precautionary statement(s)
Prevention

P264 Wash ... thoroughly after handling.

P270 Do not eat, drink or smoke when using this product.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P260 Do not breathe dust/fume/gas/mist/vapours/spray.

P273 Avoid release to the environment.

Response

P301+P310 IF SWALLOWED: Immediately call a POISON CENTER/doctor/\u2026

P321 Specific treatment (see ... on this label).

P330 Rinse mouth.

P302+P352 IF ON SKIN: Wash with plenty of water/...

P312 Call a POISON CENTER/doctor/\u2026if you feel unwell.

P361+P364 Take off immediately all contaminated clothing and wash it before reuse.

P332+P313 If skin irritation occurs: Get medical advice/attention.

P362+P364 Take off contaminated clothing and wash it before reuse.

P308+P311 IF exposed or concerned: Call a POISON CENTER/doctor/...

P391 Collect spillage.

Storage

P405 Store locked up.

Disposal

P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

Precursor and Product
Computational chemical data
  • Molecular Weight:74.14478g/mol
  • Molecular Formula:C4H12N+
  • Exact Mass:74.096974
  • Monoisotopic Mass:74.096974
  • Complexity:19.1
  • Rotatable Bond Count:0
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:0
  • Topological Polar Surface Area:0
  • Heavy Atom Count:5
  • Defined Atom Stereocenter Count:0
  • Undefined Atom Stereocenter Count:0
  • Defined Bond Stereocenter Count:0
  • Undefined Bond Stereocenter Count:0
  • Isotope Atom Count:0
  • Covalently-Bonded Unit Count:1
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  • Fax:86-571-85829153
  • Tel:86-27-13407111142
  • Fax:86-27-13407111142
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  • Fax:86-571-87396431
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