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Home> Encyclopedia > Hot Product Listed R   > Rugulosin, (1S,1'S,2R,2'R,3S,3'S,9ar,9'ar)-
1268519-74-9 structure

Rugulosin, (1S,1'S,2R,2'R,3S,3'S,9ar,9'ar)-

CAS No.:1268519-74-9
Molecular Weight:333.43
Molecular Formula:C12H11N3O3 (isomer)
Names and Identifiers
Synonyms

5H,6H-6,13A,5A,14-(1,2,3,4)Butanetetraylcycloocta(1,2-B:5,6-B')dinaphthalene-5,8,13,16(14H)-tetrone, 1,7,9,15,17,20-hexahydroxy-3,11-dimethyl-, (5ar-(5ar*,6S*,13ar*,14S*,17R*,18S*,19S*,20R*))- Radicalisin Rugulosin - forM

Properties
Density
1.098
Flash Point
235.2°C
Safety and Handling
Safety

Poison by intraperitoneal route. Questionable carcinogen with experimental tumorigenic data. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating fumes.

Toxicity
1.    

mmo-sat 10 µg/7H

    JEPTDQ    Journal of Environmental Pathology and Toxicology. 2 (2)(1978),313.
2.    

mrc-bcs 20 µg/disc

    CNREA8    Cancer Research. 36 (1976),445.
3.    

ipr-rat LD50:44 mg/kg

    JJEMAG    Japanese Journal of Experimental Medicine. 41 (1971),177.
4.    

ipr-mus LD50:55 mg/kg

    JJEMAG    Japanese Journal of Experimental Medicine. 41 (1971),177.
Report

IARC Cancer Review: Group 3 IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 7 ,1987,p. 56.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 40 ,1986,p. 99.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) ; Human No Adequate Data IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 40 ,1986,p. 99.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program.

MSDS

2.Hazard identification

2.1 Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word

Warning

Hazard statement(s)

H315 Causes skin irritation

H319 Causes serious eye irritation

Precautionary statement(s)
Prevention

P264 Wash ... thoroughly after handling.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

Response

P302+P352 IF ON SKIN: Wash with plenty of water/...

P321 Specific treatment (see ... on this label).

P332+P313 If skin irritation occurs: Get medical advice/attention.

P362+P364 Take off contaminated clothing and wash it before reuse.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P337+P313 If eye irritation persists: Get medical advice/attention.

Storage

none

Disposal

none

2.3 Other hazards which do not result in classification

none

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  • Fax:86-21-51685790
  • Tel:86-571-87396430
  • Fax:86-571-87396431
  • Tel:86-571-86960370
  • Fax:86-571-86940780
  • Tel:86-371-86658258
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