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Home> Encyclopedia > Hot Product Listed 9   > 9(10H)-Anthracenone,1,8-dihydroxy-
1143-38-0 structure

9(10H)-Anthracenone,1,8-dihydroxy-

Iupac Name:1,8-dihydroxy-10H-anthracen-9-one
CAS No.:1143-38-0
EINECS(EC#): 214-538-0
Molecular Weight:226.231
Molecular Formula:C14H10O3 (isomer)
Names and Identifiers
Synonyms

1,8 dihydroxyanthrone 1,8,9-ANTHRACENETRIOL 1,8,9-ANTHRACENETRIOL, MATRIX SUBSTANCE FOR MALDI-MS 1,8,9-ANTHRACENETRIOL, PGE. WITH 10 X 10 MG 1,8,9-Trihydroxyanthracene, 97+% 1,8-Dihydoxy-9(10H)-anthracenone 1,8-dihydroxy-10h-anthracen-9-one 1,8-dihydroxy-9(10h)-anthracenon 1,8-dihydroxy-9-(10h)anthracenone 1,8-dihydroxy-9(10h)-anthracenone 1,8-dihydroxy-9(10h)-anthracenone # 1,8-dihydroxy-9-anthrane 1,8-dihydroxy-9-anthrone 1,8-dihydroxyanthracen-9(10h)-one 1,8-dihydroxyanthrone 9(10h)-anthracenone, 1,8-dihydroxy- 9(10h)-anthracenone,8-dihydroxy- 9-anthrol AB00051916_07 AB0105711 AC-14842 AC1L1D5I AC1Q794G AJ-08003 AK481321 AN-20615 anthra-derm anthraderm (tn) Anthraforte anthralin anthralin (dithranol) anthralin (usp) anthralin, dithranol anthraline anthrone, 1,8-dihydroxy- Anthrone,1,8-dihydroxy- (6CI,7CI,8CI) anthrone,8-dihydroxy- api0002431 Batidrol batridol bdbm50041802 brn 2054360 BSPBIO_001868 C06831 CCG-38920 ccris 628 CHEBI:37510 CHEMBL46469 chrysodermol cid_2202 cignolin cigthranol CJ-00043 CS-2980 CTK8A0163 D00233 Derobin dithranol dithranol (inn) dithranol, >=90% (hplc) DITHRANOL, 97+% DITHRANOL, ANTHRALIN dithranolum [inn-latin] DIVK1C_000021 drithocreme drithoscalp DTXSID7024538 einecs 214-538-0 EPITOPE ID:114081 HMS1920E07 HMS2091K07 HMS2271B09 HMS500B03 HY-B0738 IDI1_000021 K-1044 KBIO1_000021 KBIO2_000436 KBIO2_003004 KBIO2_005572 KBIO3_001368 KBIOGR_000622 KBIOSS_000436 KS-5183 Lasan LS-570 mfcd00053409 MLS001332632 MLS002415712 MOLPORT-001-792-502 NCGC00091330-01 NCGC00091330-02 NCGC00091330-03 NCGC00091330-04 NCGC00091330-05 NCI60_004019 NINDS_000021 nsc 43970 nsc 629313 nsc43970 nsc-43970 nsc629313 nsc-629313 nuzwlkwwnnjhpt-uhfffaoysa- NUZWLKWWNNJHPT-UHFFFAOYSA-N PRESTWICK_528 psodadrate Psoriacide psoriacid-stift SC-19051 SCHEMBL3197 SPBIO_000122 SPECTRUM_000056 SPECTRUM1500127 SPECTRUM2_000111 SPECTRUM3_000304 SPECTRUM4_000151 SPECTRUM5_000820 sr-05000002011 SR-05000002011-2 ST50825759 tox21_201851 tox21_300290 U8CJK0JH5M W-108602 ZINC1322

Inchi
InChI=1S/C14H10O3/c15-10-5-1-3-8-7-9-4-2-6-11(16)13(9)14(17)12(8)10/h1-6,15-16H,7H2
InChkey
NUZWLKWWNNJHPT-UHFFFAOYSA-N
Canonical Smiles
C1C2=C(C(=CC=C2)O)C(=O)C3=C1C=CC=C3O
Properties
Appearance
yellow crystalline solid
Density
1.419
Melting Point
178-181 °C(lit.)
Boiling Point
464.1°Cat760mmHg
Vapour
5.23E-09mmHg at 25°C
Refractive Index
1.837
Flash Point
248.6°C
Solubility
<0.1g/100mLat20C
Other physical and chemical properties
PHYSICAL DESCRIPTION: Lemon yellow leaflets or plates or an orange powder. Melting point 176-181°C. No odor or taste. Insoluble in water;. Moderately toxic by ingestion, inhalation and skin absorption. Used as a treatment for psoriasis.
Stability
Stable. Combustible. Incompatible with strong oxidizing agents.
HS Code
29144000
Storage temp
2-8°C
Safety and Handling
Hazard Codes
Xi
Risk Statements
R36/37/38
Safety Statements
26-53-45
Safety

A mild skin irritant. When heated to decomposition it emits acrid smoke and irritating vapors.
Hazard Codes:
Xi: Irritant
T: Toxic
Risk Statements about 1,8-Dihydroxy-anthrone (1143-38-0):
R45 May cause cancer.
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements about 1,8-Dihydroxy-anthrone (1143-38-0):
S26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
S45 In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
S53 Avoid exposure - obtain special instructions before use.

Toxicity
1.    

skn-hmn 0.1%/20M MLD

    ADVEA4    Acta Dermato-Venereologica. 67 (1987),72.
2.    

skn-hmn 0.05%/12H

    ADVEA4    Acta Dermato-Venereologica. 18 (1988),117.
3.    

skn-hmn 0.1%/1H MLD

    ADVEA4    Acta Dermato-Venereologica. 67 (1987),72.
4.    

skn-hmn 0.0025%/24H MLD

    ADVEA4    Acta Dermato-Venereologica. 63 (1983),513.
5.    

skn-hmn 0.01%/24H open

    ADVEA4    Acta Dermato-Venereologica. 173 (1986),288.
6.    

skn-hmn 0.02%/48H MOD

    ADVEA4    Acta Dermato-Venereologica. 93 (1989),695.
MSDS

2.Hazard identification

2.1 Classification of the substance or mixture

Skin irritation, Category 2

Eye irritation, Category 2

Specific target organ toxicity \u2013 single exposure, Category 3

2.2 GHS label elements, including precautionary statements

Pictogram(s)
Signal word

Warning

Hazard statement(s)

H315 Causes skin irritation

H319 Causes serious eye irritation

H335 May cause respiratory irritation

Precautionary statement(s)
Prevention

P264 Wash ... thoroughly after handling.

P280 Wear protective gloves/protective clothing/eye protection/face protection.

P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

P271 Use only outdoors or in a well-ventilated area.

Response

P302+P352 IF ON SKIN: Wash with plenty of water/...

P321 Specific treatment (see ... on this label).

P332+P313 If skin irritation occurs: Get medical advice/attention.

P362+P364 Take off contaminated clothing and wash it before reuse.

P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

P337+P313 If eye irritation persists: Get medical advice/attention.

P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P312 Call a POISON CENTER/doctor/\u2026if you feel unwell.

Storage

P403+P233 Store in a well-ventilated place. Keep container tightly closed.

P405 Store locked up.

Disposal

P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification

none

Precursor and Product
Computational chemical data
  • Molecular Weight:226.231g/mol
  • Molecular Formula:C14H10O3
  • Compound Is Canonicalized:True
  • Exact Mass:226.063
  • Monoisotopic Mass:226.063
  • Complexity:287
  • Rotatable Bond Count:0
  • Hydrogen Bond Donor Count:2
  • Hydrogen Bond Acceptor Count:3
  • Topological Polar Surface Area:57.5A^2
  • Heavy Atom Count:17
  • Defined Atom Stereocenter Count:0
  • Undefined Atom Stereocenter Count:0
  • Defined Bond Stereocenter Count:0
  • Undefined Bond Stereocenter Count:0
  • Isotope Atom Count:0
  • Covalently-Bonded Unit Count:1
  • CACTVS Substructure Key Fingerprint: AAADccBwMAAAAAAAAAAAAAAAAAAAAAAAAAAwYMAAAAAAAADBQAAAGgAACAAADASAmAAwBoAAAgCI AqBSAAACAAAkIAAIiAEGCMgIJjaCFRKAcUAk4BEImQeI6PSOgAABAAAYAACAAAYAADAAAAAAAAAA AA==
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