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Home> Hot Product Listed Z   > Zinc oxide

Zinc oxide

CAS No.:1314-13-2
Molecular Weight:81.39
Molecular Formula:ZnO (Products with the same molecular formula)
MOL File:1314-13-2.mol
white powder
Melting Point
Boiling Point
Refractive Index
Flash Point
1.6 mg/L (29℃)
1.6 mg/L (29 ℃) in Water
White or yellowish-white powder; hexagonal crystals
Coarse white or grayish powder
Hexagonal, wurtzite crystal structure
Stable. Incompatible with magnesium, strong acids.
HS Code
Storage temp
Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Spectral properties
Index of refraction: 2.0041, 2.0203
Safety and Handling
Hazard Codes
N:Dangerous for the environment
Risk Statements
Safety Statements
A skin irritant. When heated to decomposition it emits toxic fumes of ZnO. See also ZINC OXIDE and ZINC COMPOUNDS.
Safety Information of Zinc oxide (CAS NO.1314-13-2):
Hazard Codes: NDangerous for the environment
Risk Statements: R50/53
R50/53:Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment.
Safety Statements: S60;S61
S60:This material and its container must be disposed of as hazardous waste.
S61:Avoid release to the environment. Refer to special instructions / safety data sheets.
Cleanup Methods
Sweep spilled substance into containers; if appropriate, moisten first to prevent dusting. Carefully collect remainder, then remove to safe place.
UN 3077 9/PG 3
Fire Fighting Procedures
In case of fire in the surroundings: use appropriate extinguishing media.
Fire Potential
Not combustible.
Contact with water liberates highly flammable gases.
Zinc oxide is incorporated in powders, ointments, and pastes. Preparation containing zinc oxide including zinc oxide ointment (20% or 25% ZnO), zinc oxide paste (25% ZnO), and zinc oxide and salicylic acid paste (2% salicylic acid in zinc oxide paste).
Calamine consists of pink powder containing zinc oxide (not less than 98%) and small amont of ferric oxide. It is incorporated into calamine lotion (8% calamine and 8% zinc oxide), and phenolated calamine lotion (compound calamine lotion) (1% phenol in calamine lotion).
The medicinal grade contains 99.5% or more ZnO; technical grades contain 90-99% ZnO and a few tenths of 1% of lead.
Grades: American process, lead-free; French process, lead-free, green seal, red seal, white seal (according to fineness); leaded (with lead sulfate); USP, single crystals.
Zinc oxide preparations: Bandages: Zinc Paste and Coal Tar Bandage, not less than 6% zinc oxide; Zinc Paste and Ichthammol Bandage, zinc oxide 6.25 g per 100 g; Zinc Paste Bandge, not less than 6% zinc oxide; Zinc Paste, Calamine and Clioquinol Bandage, zinc oxide 9.25 g per 100 g; Creams: Zinc and Ichthammol Cream, zinc cream 82 g per 100 g; Zinc Cream, zinc oxide 32 g per 100 g; Zinc Cream Oily, zinc oxide 32 g per 100 g; Zinc Oxide and Diphenhydramine Cream, zinc oxide 8 g per 100 g; Dental Cements: Zinc-Eugenol Cement; Kerr's Sealer; Dental Paste: Dental Triozinc Paste; Dusting-powders: Cmpd Zinc Dusting-powder; Conspergens Zinci; Zinc and Salicylic Acid Dusting-powder; Zinc, Starch, and Talc Dusting-powder; Gauzes: Zinc Gelatin Impregnated Gauze; Liniments: Linimentum Phenoli et Zinci Oxydi; Linimentum Zinci; Lotions: Lotions F; Schamberg's Lotion; Zinc Talc Lotion; Ointments: Hamer's Hemorrhoidal Ointment; Zinc and Caster Oil Ointment; Zinc Ointment; Zinc Oxide and Ichthammol Ointment; Zinc oxide cmpd ointment; Pastes: Cmpd Zinc Paste; Zinc Gelatin
Proprietary preparations: Calaband, Coltapaste, Ichthopaste, Icthaband, Noratex, Pharmakon, Quinaband, Septex Cream No1, Sudocrem, Tarband, Thovaline, Impregnated Gauze, Viscopaste, Viscopaste PB7, Zincaband; Herisan; Oxyplastine
/Transparent Zinc Oxide/ Trade names include Sachtotech Micro-Zinkoxid (Sachtleben, Germany) and Z-cote HP 1 (SunSmart, United States).
Trade Names: Akro-Zinc Bar 85; Acro-Zinc Bar 90; Actox 14; Actox 16; Actox 216; Amalox; Azodox; Azo 22; Azo 33; Azo 55; Azo 66; Azo 77TT; Cador XX 78; Chinese white; CI77947; CIPigment White 4; Emanay Zinc Oxide; Emar; Felling Zinc Oxide; Flores de Zinci; Flowers of Zinc; Green Seal 8; Hubbuck's White; Kadox 15; Kadox 72; Kadox 25; Outmine; Ozide; Ozlo; Permanent White; Philosopher's Wool; Powder Base 900; Protox types 166, 167, 168, 169, 267, 268; Red Seal 9; Snow White; Unichem ZO; Vandem VAC; Vandem VOC; Vandem VPC; White Seal 7; XX 203; XX 78; Zinc White; Zinca 20; Zincite; Zincoid; Zn 0701T; Electrox 2500; GIAP 10; Outmine; Unichem ZO; XX 601
Wettable powder - 202.76% zinc oxide; Metal strip - 99.1% zinc; Powder - 99% zinc oxide (formulation intermediate); Powder - 99.4% zinc oxide (industrial preservative).
Exposure Standards and Regulations
The Approved Drug Products with Therapeutic Equivalence Evaluations List identifies currently marketed prescription drug products, incl zinc oxide, approved on the basis of safety and effectiveness by FDA under sections 505 of the Federal Food, Drug, and Cosmetic Act.
Certification of this color additive when used for coloring externally applied drugs, including those used in the area of the eye, in amounts consistent with good manufacturing practice is not necessary for the protection of the public health, and therefore batches thereof are exempt from the certification pursuant to section 721(c) of the act.
Certification of this color additive when used in cosmetics, including cosmetics intended for use in the area of the eye, in amounts consistent with good manufacturing practice is not necessary for the protection of the public health, and therefore batches thereof are exempt from the certification pursuant to section 721(c) of the act.
This substance is generally recognized as safe when used as a nutrient in accordance with good manufacturing practice.
Drug products containing active ingredients offered over-the-counter (OTC) for the treatment of boils. Zinc oxide is included in this section.
Drug products containing certain active ingredients offered over-the-counter (OTC) for certain uses. A number of active ingredients have been present in OTC drug products for various uses, as described below. However, based on evidence currently available, there are inadequate data to establish general recognition of the safety and effectiveness of these ingredients for the specified uses: zinc oxide is included in topical acne drug products.
Drug products containing certain active ingredients offered over-the-counter (OTC) for certain uses. A number of active ingredients have been present in OTC drug products for various uses, as described below. However, based on evidence currently available, there are inadequate data to establish general recognition of the safety and effectiveness of these ingredients for the specified uses: zinc oxide is included in external analgesic drug products (insect bite and sting).
Sunscreen active ingredients. The active ingredient of the product consists of any of the following, within the concentration specified for each ingredient, and the finished product provides a minimum SPF value of not less than 2 as measured by the testing procedures established in subpart D of this part: zinc oxide up to 25 percent is included on this list.
Trace minerals added to animal feeds as nutritional dietary supplements are generally recognized as safe when added at levels consistent with good feeding practice. Zinc oxide is included on this list.
This substance is generally recognized as safe when used as a nutrient and/or dietary supplement in accordance with good manufacturing or feeding practice.
Reactivities and Incompatibilities
Slow addition of zinc white (a voluminous oxide containing much air) to cover the surface of linseed oil varnish caused generation of heat and ignition. Lithopone, a denser (air-free) grade of oxide did not cause heating.
Magnesium will reduce /zinc/ oxide violently on heating, similar to aluminium powder in the thermite reaction. /Magnesium: metal oxides/
Intimate mixtures of chlorinated rubber and zinc oxide with or without hydrocarbon or chlorinated solvents, react violently or explosively when heated at about 216 deg C. If in milling such mixtures local overheating occurs, a risk of a violent reaction exists. Such risks can be minimized by controlling milling temperatures, by cooling, or by using a mixture of maximum possible fluidity. /Chlorinated rubber: metal oxides or hydroxides/
Zinc oxide reacts with carbon monoxide or hydrogen to produce /elemental zinc/.
Presence of zinc oxide causes flaming decomp /of hydrazinium nitrate/ above the melting point (70 deg C). /Hydrazinium nitrate: alone, etc/
Other Preventative Measures
Exhaust ventilation is the most effective control of freshly generated zinc oxide fumes. Education of metal repair persons as to the hazards and proper use of temporary ventilation for large repair jobs is essential.
Prevention /of metal fume fever/ is a matter of keeping exposure of workers below level of concn currently accepted as satisfactory for working with the metal in industry, preferably by employment of proper local exhaust ventilation to collect fumes at their source. Acceptable respirators are avail commercially but should be used only under suitable conditions. /Zinc/
Do not eat, drink, or smoke during work.
In all cases where zinc is heated to the point where fume is produced, it is most important to ensure that adequate ventilation is provided. Individual protection is best ensured by education of the worker concerning metal-fume fever & the provision of local exhaust ventilation, or, in some situations by wearing of supplied-air hood or mask.
Protective Equipment and Clothing
Respirator Recommendations: Up to 50 mg/cu m: (Assigned Protection Factor = 10) Any particulate respirator equipped with an N95, R95, or P95 filter (including N95, R95, and P95 filtering face quarter-mask respirators. The following filters may also be used: N99, R99, P99, N100, R100, P100)./(Assigned Protection Factor = 10) Any supplied-air respirator.
Respirator Recommendations: Up to 125 mg/cu m: (Assigned Protection Factor = 25) Any supplied-air respirator operated in a continuous flow mode./(Assigned Protection Factor = 25) Any powered, air-purifying respirator with a high-efficiency particulate filter.
Respirator Recommendations: Up to 250 mg/cu m: (Assigned Protection Factor = 50) Any air-purifying, full-facepiece respirator with an N100, R100, or P100 filter./(Assigned Protection Factor = 50) Any supplied-air respirator that has a tight-fitting facepiece and is operated in a continuous-flow mode./(Assigned Protection Factor = 50) Any powered, air-purifying respirator with a tight-fitting facepiece and a high-efficiency particulate filter./(Assigned Protection Factor = 50) Any self-contained breathing apparatus with a full facepiece./(Assigned Protection Factor = 50) Any supplied-air respirator with a full facepiece.
Respirator Recommendations: Up to 500 mg/cu m: (Assigned Protection Factor = 1000) Any supplied-air respirator operated in a pressure-demand or other positive-pressure mode.
Respirator Recommendations: Emergency or planned entry into unknown concentrations or IDLH conditions: (Assigned Protection Factor = 10,000) Any self-contained breathing apparatus that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode./(Assigned Protection Factor = 10,000) Any supplied-air respirator that has a full facepiece and is operated in a pressure-demand or other positive-pressure mode in combination with an auxiliary self-contained positive-pressure breathing apparatus.
Respirator Recommendations: Escape: (Assigned Protection Factor = 50) Any air-purifying, full-facepiece respirator with an N100, R100, or P100 filter./Any appropriate escape-type, self-contained breathing apparatus.
A properly fitting respirator with a filter cartridge suitable for fumes is effective in unusual jobs requiring respirators for short exposures.
Zinc oxide's CAS NO. is 1314-13-2, the synonyms are Zinc white ; C.I. pigment white 4 . Zinc oxide (CAS NO.1314-13-2) is an inorganic compound with the formula ZnO. It usually appears as a white powder, nearly insoluble in water. The powder is widely used as an additive into numerous materials and products including plastics, ceramics, glass, cement, rubber (e.g. car tyres), lubricants, paints, ointments, adhesives, sealants, pigments, foods (source of Zn nutrient), batteries, ferrites, fire retardants, etc. ZnO is present in the Earth crust as a mineral zincite; however, most ZnO used commercially is produced synthetically.
Zinc and its compounds are on the Community Right-To-Know List.
Disposal Methods

SRP: The most favorable course of action is to use an alternative chemical product with less inherent propensity for occupational exposure or environmental contamination. Recycle any unused portion of the material for its approved use or return it to the manufacturer or supplier. Ultimate disposal of the chemical must consider: the material's impact on air quality; potential migration in soil or water; effects on animal, aquatic, and plant life; and conformance with environmental and public health regulations.
Chemical Treatability of Zinc; Concentration Process: Ultrafiltration; Chemical Classification: Metals; Scale of Study: Continuous flow, pilot scale; Type of Wastewater Used: Industrial wastewater; Results of Study: 0.38 ppm effluent concentration. /Zinc/
Chemical Treatability of Zinc; Concentration Process: Miscellaneous sorbents; Chemical Classification: Metals; Scale of Study: Literature review; Type of Wastewater Used: Unknown; Results of Study: Final concentration reduced to 0.1 ppb; SiO2 + CaO slags used. /Zinc/

Reach Info
This substance has been officially registered by enterprises.
ECHA (EU chemicals Management Agency) published the completed registration file as follows:
Completed registration file:
Registered as ubmitted Total tonnage band  
FULL JOINT 100000_1000000 view >
Registered companies:
Registrant / Supplier details Latest dossier received
3M Italia s.r.l. 2016
AFC 2013
more >

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According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017


1.1 GHS Product identifier

Product name zinc oxide

1.2 Other means of identification

Product number -
Other names Zinc oxide

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

Company WWW.GuideChem.COM
Address 8F, Block C, No.3 Building, Zijin Plaza, No.701, Gudun Road, Hangzhou, Zhejiang 310030, China
Telephone +86-571-89739798
Fax 86(21)54365166

1.5 Emergency phone number

Emergency phone number +86-571-89739798
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

2.Hazard identification

2.1 Classification of the substance or mixture

Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

2.2 GHS label elements, including precautionary statements

Signal word


Hazard statement(s)

H410 Very toxic to aquatic life with long lasting effects

Precautionary statement(s)

P273 Avoid release to the environment.


P391 Collect spillage.




P501 Dispose of contents/container to ...

2.3 Other hazards which do not result in classification


3.Composition/information on ingredients

3.1 Substances

Chemical name Common names and synonyms CAS number EC number Concentration
zinc oxide zinc oxide 1314-13-2 none 100%

4.First-aid measures

4.1 Description of necessary first-aid measures

General advice

Consult a physician. Show this safety data sheet to the doctor in attendance.

If inhaled

If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

In case of skin contact

Wash off with soap and plenty of water. Consult a physician.

In case of eye contact

Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

If swallowed

Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

4.2 Most important symptoms/effects, acute and delayed

no data available

4.3 Indication of immediate medical attention and special treatment needed, if necessary

no data available

5.Fire-fighting measures

5.1 Extinguishing media

Suitable extinguishing media

Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

5.2 Specific hazards arising from the chemical

no data available

5.3 Special protective actions for fire-fighters

Wear self-contained breathing apparatus for firefighting if necessary.

6.Accidental release measures

6.1 Personal precautions, protective equipment and emergency procedures

Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

6.2 Environmental precautions

Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.

6.3 Methods and materials for containment and cleaning up

Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

7.Handling and storage

7.1 Precautions for safe handling

Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

7.2 Conditions for safe storage, including any incompatibilities

Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

8.Exposure controls/personal protection

8.1 Control parameters

Occupational Exposure limit values

no data available

Biological limit values

no data available

8.2 Appropriate engineering controls

Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

8.3 Individual protection measures, such as personal protective equipment (PPE)

Eye/face protection

Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

Skin protection

Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

Respiratory protection

Wear dust mask when handling large quantities.

Thermal hazards

no data available

9.Physical and chemical properties

Physical state white powder
Colour no data available
Odour no data available
Melting point/ freezing point 1975\u00baC
Boiling point or initial boiling point and boiling range 2360\u00baC
Flammability no data available
Lower and upper explosion limit / flammability limit no data available
Flash point 12\u00b0C
Auto-ignition temperature no data available
Decomposition temperature no data available
pH no data available
Kinematic viscosity no data available
Solubility In water:1.6 mg/L (29 \u00baC)
Partition coefficient n-octanol/water (log value) no data available
Vapour pressure no data available
Density and/or relative density 1.25g/mL\u00b10.05g/mLat 25\u00b0C
Relative vapour density no data available
Particle characteristics no data available

10.Stability and reactivity

10.1 Reactivity

no data available

10.2 Chemical stability

Stable under recommended storage conditions.

10.3 Possibility of hazardous reactions

no data available

10.4 Conditions to avoid

no data available

10.5 Incompatible materials

no data available

10.6 Hazardous decomposition products

no data available

11.Toxicological information

Acute toxicity

  • Oral: no data available
  • Inhalation: no data available
  • Dermal: no data available

Skin corrosion/irritation

no data available

Serious eye damage/irritation

no data available

Respiratory or skin sensitization

no data available

Germ cell mutagenicity

no data available


no data available

Reproductive toxicity

no data available

STOT-single exposure

no data available

STOT-repeated exposure

no data available

Aspiration hazard

no data available

12.Ecological information

12.1 Toxicity

  • Toxicity to fish: no data available
  • Toxicity to daphnia and other aquatic invertebrates: no data available
  • Toxicity to algae: no data available
  • Toxicity to microorganisms: no data available

12.2 Persistence and degradability

no data available

12.3 Bioaccumulative potential

no data available

12.4 Mobility in soil

no data available

12.5 Other adverse effects

no data available

13.Disposal considerations

13.1 Disposal methods


The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

Contaminated packaging

Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

14.Transport information

14.1 UN Number

ADR/RID: UN3077 IMDG: UN3077 IATA: UN3077

14.2 UN Proper Shipping Name


14.3 Transport hazard class(es)


14.4 Packing group, if applicable


14.5 Environmental hazards

ADR/RID: yes IMDG: yes IATA: yes

14.6 Special precautions for user

no data available

14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

no data available

15.Regulatory information

15.1 Safety, health and environmental regulations specific for the product in question

Chemical name Common names and synonyms CAS number EC number
zinc oxide zinc oxide 1314-13-2 none
European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
EC Inventory Listed.
United States Toxic Substances Control Act (TSCA) Inventory Listed.
China Catalog of Hazardous chemicals 2015 Not Listed.
New Zealand Inventory of Chemicals (NZIoC) Listed.
Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
Vietnam National Chemical Inventory Listed.
Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.

16.Other information

Information on revision

Creation Date Aug 12, 2017
Revision Date Aug 12, 2017

Abbreviations and acronyms

  • CAS: Chemical Abstracts Service
  • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
  • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
  • IMDG: International Maritime Dangerous Goods
  • IATA: International Air Transportation Association
  • TWA: Time Weighted Average
  • STEL: Short term exposure limit
  • LC50: Lethal Concentration 50%
  • LD50: Lethal Dose 50%
  • EC50: Effective Concentration 50%


  • IPCS - The International Chemical Safety Cards (ICSC), website:
  • HSDB - Hazardous Substances Data Bank, website:
  • IARC - International Agency for Research on Cancer, website:
  • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website:
  • CAMEO Chemicals, website:
  • ChemIDplus, website:
  • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website:
  • Germany GESTIS-database on hazard substance, website:
  • ECHA - European Chemicals Agency, website:

Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.

Computational chemical data

Molecular Weight:81.4084 [g/mol]
Molecular Formula:OZn
H-Bond Donor:0
H-Bond Acceptor:1
Rotatable Bond Count:0
Exact Mass:79.924061
MonoIsotopic Mass:79.924061
Topological Polar Surface Area:17.1
Heavy Atom Count:2
Formal Charge:0
Isotope Atom Count:0
Defined Atom Stereocenter Count:0
Undefined Atom Stereocenter Count:0
Defined Bond Stereocenter Count:0
Undefined Bond Stereocenter Count:0
Covalently-Bonded Unit Count:1