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Home> Products> Pharmaceuticals and Biochemicals > Hormones and synthetic substitutes >

How to buy Formestane 566-48-3 566-48-3 Purity 99% YD Customized China

How to buy Formestane 566-48-3
CAS: 566-48-3
FOB Price:1 USD/Gram
Port:Hongkong
Minimum Order Quantity:10 Gram
Supply Ability:100 Kilogram/Month
Updatetime:Sep 21 2016
Company Profile
Contact:David Chen
Phone:86-17321455661
Tel:86-27-68580270
Fax:86-27-68580270
Address: 28# Golden Avenue, Golden Industrial Zone, Zhengdian Street, Jiangxia District, Wuhan City, Hubei, P. R. China
Quick Details
Classification: Hormones and synthetic substitutes
Cas NO.: 566-48-3
Name: Formestane
Molecular Formula: C19H26O3
Melting Point: 199-202°C
Boiling Point: 475.4°Cat760mmHg
Refractive index:1.545
Flash Point: 255.4°C
Purity: 99%
Appearance: White powder.
usage: Estrogen
Brand Name: YD
Aliase: Formestane
Purity: 99%
Appearance:white or off-white crystalline powder
Brand: YD
Name: Formestane
Usage: aromatase inhibitors ,it is used for progressive breast cancer. male hormones, assimilating protein class.
Packaging & Delivery
Packaging Detail: Customized
Delivery Detail: 3days
Detailed Description

Formestane


1. Quick Details:

Synonyms: 4-hydroxy-androst-4-ene-17-dione;4-hydroxy-delta(sub4)-androstenedione;4-HYDROXYANDROST-4-ENE-3,17-DIONE;4-HYDROXYANDROSTENEDIONE;4-HYDROXY-4-ANDROSTENE-3,17-DIONE;4-ANDROSTEN-4-OL-3,17-DIONE;4-OHA;CGP-32349

CAS: 566-48-3

MF: C19H26O3

MW: 302.41


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a. Fast Delivery: 3 work days after received payment.

b. Free Resending: For long term cooperation, we guarantee all our customers will get their stuffs. 

c. Long Term Cooperation Discount: 5% DISCOUNT for our regular customers.


3. Hot sell:


Injection liquid

Name Specification

Deca 200 200mg/ml

Deca 250 250mg/ml

Anadrol 50 50mg/ml

Anavar 50 50mg/ml

Anomass 400 400mg/ml

Boldenone Acetate 100 100mg/ml

 (Boldenone Cypionate) 200mg/ml

(Boldenone undecylenate) 300mg/ml

Clomid 50 50mg/ml

Cypoject 250 (Testosterone Cypionate) 600mg/ml

Dianabol 250 250mg/ml

Durabolin 250 250mg/ml

Enanject 250 (Testosterone Enanthate) 250mg/ml

Enanject 600 (Testosterone Enanthate) 600mg/ml

Femara 5 5mg/ml

NPP 200 200mg/ml

 (Nandrolone Cypionate) 200mg/ml

Nolvadex 20 20mg/ml

Winstrol 50 50mg/ml

Propionat 100 (Testosterone Propionate) 100mg/ml

Propionat 200 (Testosterone Propionate) 200mg/ml

Sustanon 200 200mg/ml

Sustanon 250 250mg/ml

Sustanon 300 300mg/ml

Sustanon 400 400mg/ml

Undecanoate 500 (Testosterone Undecanoate) 500mg/ml

Trenabol 100 100mg/ml

Trenabolic 80 (Trenbolone Acetate) 80mg/ml

Trenabolic 100 (Trenbolone Acetate) 100mg/ml

Trenabolic 200 (Trenbolone Acetate) 200mg/ml

Trenaject 60 (Trenbolone enanthate) 60mg/ml

Trenaject 100 (Trenbolone Enanthate) 100mg/ml

Trenaject 150 (Trenbolone Enanthate) 150mg/ml

Trenaject 200 (Trenbolone Enanthate) 200mg/ml

Parabolone 50 (Tren hex) 50mg/ml

Masteron 100 (Drostanolone Propionate) 100mg/ml

Masteron 200 (Drostanolone Enanthate) 200mg/ml

Primoject 100 (Methenolone Enanthate) 100mg/ml

TMT Blend 375 (Trenbolone Enanthate 125mg/ml; Drostanolone Enanthate 125mg/ml;Testosterone Enanthate 125mg/ml)

TM Blend 500(Trenbolone Enanthate 250mg/ml Drostanolone Enanthate 250mg/ml)


Raw Powder

1 Testosterone enanthate CAS: 315-37-7

2 Testosterone acetate CAS: 1045-69-8

3 Testosterone propionate CAS: 57-85-2

5 Testosterone cypionate CAS: 58-20-8

6 Testosterone phenylpropionate CAS: 1255-49-8

7 Testosterone isocaproate CAS: 15262-86-9

8 Testosterone decanoate CAS: 5721-91-5

9 Testosterone Sustanon 250

10 Testosterone undecanoate CAS: 5949-44-0

11 Turinabol (4-Chlorotestosterone acetate)       CAS:  855-19-6

12 Oral turinabol CAS: 2446-23-3

13 Stanolone (androstanolone) CAS: 521-18-6

14 Nandrolone Decanoate (DECA) CAS: 360-70-3

15 Nandrolone Cypionate CAS: 601-63-8

16 Nandrolone Phenypropionate (Durabolin) CAS: 62-90-8

17 Boldenone Undecylenate (Equipoise) CAS: 13103-34-9

18 Boldenone Acetate CAS :2363-59-9

19 Drostanolone Propionate (Masteron) CAS: 521-12-0

20 Drostanolone Enanthate CAS: 472-61-1

21 Superdrol Powder (methyl-drostanolone) CAS: 3381-88-2

22 Trenbolone Acetate (Finaplix H/Revalor-H) CAS: 10161-34-9

23 Trenbolone Enanthate (parabolan) CAS: 10161-33-8

24 Trenbolone Hexahydrobenzyl Carbonate CAS: 23454-33-3

25 Epiandrosterone CAS: 481-29-8

26 Dehydroisoandrosterone Acetate CAS: 853-23-6

27 CAS: 566-19-8

28 Methenolone Enanthate (Primobolan) CAS: 303-42-4

29 Methenolone Acetate CAS: 434-05-9

30 Methandrostenolone(Dianabol) CAS: 72-63-9

31 Tamoxifen Citrate (Nolvadex) CAS: 54965-24-1

32 Clomiphene citrate CAS: 50-41-9

33 Toremifene citrate CAS: 89778-27-8

34 Letrazole(Femara) CAS: 112809-51-5

35 vardenafil CAS: 831217-01-7

36 Dapoxetine CAS: 119356-77-3

37 Dapoxetine HCl CAS: 1071929-03-7

38 Dutasteride CAS: 164656-23-9

39 Finasteride CAS: 98319-26-7

40 Yohimbine HCl CAS: 65-19-0

MGF                                           (2mg/vial)

CJC-1295DAC 863288-34-0                       (2mg/vial)

PT-141 32780-32-8                             (10mg/vial)

Melanotan-II                                 (10mg/vial)

GHRP-6 87616-84-0                             (5mg/vial)

Hexarelin  140703-51-1                       (2mg/vial)

Oxytocin                                     (2mg/vial)

pentadecapeptide BPC 157                     (2mg/vial)

Triptorelin Acetate                           (2mg/vial)

Tesamorelin 106612-94-6                       (2mg/vial)

Selank                                       (5mg/vial)

Carbetocin Acetate 37025-55-1                 (1G / foil bag)

EGF 62253-63-8                       (1KG / fluorinated bottle)

Thymosin α1 Acetate 62304-98-7         (1G / polypeptide tube)

PEG-MGF                                       (2mg/vial)

CJC-1295                                     (2mg/vial)

Melanotan-I                                   (10mg/vial)

GHRP-2 158861-67-7                           (5mg/vial)

Ipamorelin 170851-70-4                       (2mg/vial)

Sermorelin 86168-78-7                         (2mg/vial)

TB500  75591-33-4                             (2mg/vial)

Fragment 176-191                       (2mg/vial)

Gonadorelin Acetate 34973-08-5               (2mg/vial)

DSIP 62568-57-4                               (2mg/vial)

AOD-9604 221231-10-3                         (1G / foil bag)

Desmopressin acetate 16789-98-3               (1G / foil bag)

Eptifibatide 188627-80-7                     (1G / foil bag) 

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4. More Information About Formestane:


Formestane is a steroidal aromatase inhibitor, known as a suicidal inhibitor because it permanently binds to the aromatase enzyme.


Formestane was originally used as an injectable for breast cancer patients, but due to its possible androgenic effects it has largely been replaced by non-steroidial AIs in the medical community. Most of its use is now is limited to the bodybuilding community since it is available as a legal dietary supplement for reducing estrogen and increasing testosterone production.

Although formestane can effectively reduce estrogen through oral consumption, its low oral bioavailability has lead to the development of several transdermal based products (which appear to offer higher efficacy at a lower dose).

Relative to 6-oxo and ATD, Formestane is a more potent aromatase inhibitor, which appears to effectively reduce natural estrogen levels by as much as 50% within several days (while higher doses may further suppress estrogen). Because of formestanes potent ability at reducing estrogen it will tend to reduce HDL levels, while increasing LDL levels, thus harming the cholesterol profile. For this reason, it is recommended to limit cycles of formestane to 8 weeks max.

Because formestane also has a strong affinity for the 5a-reductase enzyme it will reduce DHT levels in the body by effectively competing with testosterone for the 5a-reductase.

Formestane converts to the active androgen 4-hydroxytestosterone which has about half the anabolic potency, and about 25% of the androgenic potency as testosterone. This would suggest that fairly high doses of formestane (800-1000mg/day) could lead to some level of anabolic enhancement (although the amount required for this would surely lead to undesirably low estrogen levels).


Formestane is successfully used as a standalone during re-composition cycles to help reduce “bloat” and fat storage. It can also be used as an anti-estrogen to counter aromatization of aromatizing steroids.

Formestane (4-hydroxyandrostenedione) is an aromatase inhibitor which significantly reduces plasma levels of estrogen and has shown antitumour activity in postmenopausal women with breast cancer. Objective response rates in heavily pretreated patients with advanced breast cancer generally range between 20 and 30% during treatment with intramuscular formestone 250 or 500mg once every 2 weeks, and a further 20 to 30% of patients experience disease stabilisation. The median duration of response is between 8 and 14 months. Highest response rates are observed in soft tissue metastases, in patients with estrogen-responsive tumours and in those showing a response to previous endocrine therapy. Furthermore, there is some evidence to suggest that higher response rates are achieved with formestane 500 versus 250mg once every 2 weeks. In comparative studies, the clinical efficacy of intramuscular formestane 250mg did not differ significantly from that of oral megestrol when administered as second-line endocrine therapy to patients with advanced disease in whom previous tamoxifen therapy had failed. In addition, formestane produced a response rate, duration of response and overall survival rate that was not significantly different from that of oral tamoxifen when administered as first-line endocrine therapy to patients with advanced disease, but tamoxifen was superior in some measures. Further investigation of these 2 agents, including the higher dosage of formestane (500mg), is necessary to confirm their relative efficacies. Formestane is well tolerated by the majority of patients; adverse events rarely necessitate cessation of therapy. The most common adverse events are local reactions at the injection site and systemic events usually related to the effect of the drug on the hormonal milieu. The systemic tolerability of formestane is similar to that of tamoxifen but better than that of megestrol. Thus, formestane is effective and well tolerated as first-line endocrine therapy for advanced disease. However, at present, it is unlikely to challenge tamoxifen in this indication, based on recent findings from a large comparative study and the fact that formestane requires intramuscular administration. Nonetheless, formestane, which appears to have a better tolerability profile than other currently available second-line agents (including megestrol and the aromatase inhibitor aminoglutethimide), is a valuable drug for the second-line treatment of postmenopausal women with advanced breast cancer.


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6. Seller's Information:


Company: Shanghai Yijing Pharmaceutical Co., Ltd

 

7. How to place an order:


Send me an email at the address above, tell me product name and quantity.

Company Information
Hubei Yuancheng Saichuang Technology Co., Ltd
Name:Hubei Yuancheng Saichuang Technology Co., Ltd √ Verified
Category:Individual (Sole proprietorship)
Trade Category: Manufacturer√ Verified
Registered Time: 2002 √ Verified
Registered Capital: US$5 Million - US$10 Million
Legal Representative: evelyn@chembj.com√ Verified
Employees: 501 - 1000 People
Address: 28# Golden Avenue, Golden Industrial Zone, Zhengdian Street, Jiangxia District, Wuhan City, Hubei, P. R. China
Product/Service: Anabolic Steroid Hormone Powder, Muscle Building Steroids, Oral Anabolic Steroids, Injectable Anabolic Steroids, Pharmaceutical Raw Materials, Food Additives, Flavor&,Fragrance

Hubei Yuancheng Saichuang Technology Co., Ltd, a leading manufacturer and supplier of Anabolic Steroid Hormone Powders, Pharmaceutical raw materials, Pharmaceutical Intermediates, Chemical raw materials, Food additives and Flavor & Fragrance in China. It was founded in 2002, located in Wuhan City Hubei Province. Wuhan, the capital of Hubei Province, as the political, economic and cultural center as well as a regional commercial trade center, its unique geographical and cultural conditions are favorable for domestic and foreign trade. Integrating research, production, process and sales, we are mainly specialized in manufacturing and exporting anabolic steroid hormone raw powders and pharmaceutical raw materials. The company has invested large fund and brains into R&D department to .....more>>

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